{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T21:29:29Z","timestamp":1764883769463,"version":"3.46.0"},"reference-count":32,"publisher":"BMJ","issue":"11","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"unspecified","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR303255"],"award-info":[{"award-number":["NIHR303255"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,10,2]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Being able to talk about the anticipated course of living with an illness is essential to delivering and receiving person-centred care. Despite clinical heart failure guidance encouraging these prognostic conversations at all stages of disease, they occur infrequently or very late in the disease course. This qualitative synthesis will use the Joanna Briggs Institute (JBI) meta-aggregation approach to explore how prognostic conversations are currently taking place, what people think about prognostic conversations, and how people experience them.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This systematically conducted qualitative synthesis, using JBI meta-aggregation, considers qualitative evidence that explores the prognostic communication experiences, attitudes or practices of people with heart failure and their healthcare professionals. Prognostic communication is defined as a verbal interaction about anticipated changes to symptoms or function, possibility of unpredictable events, potential future treatments or care, expression of wishes about the future, or estimates of life expectancy. It will include interactions occurring in any setting (inpatient, outpatient, community). Exclusion criteria include studies of carer perspectives, discussion about implantable cardiac defibrillator deactivation, assisted dying and\/or euthanasia, and those not published in the English language. Medical Literature Analysis and Retrieval System Online (MEDLINE) (Ovid), Excerpta Medica Database (EMBASE) (Ovid), PsycInfo (Ovid), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus (EBSCOhost), Web of Science Core, Overton, ProQuest Dissertations and Theses Global, and Google Scholar databases will be searched for eligible studies. Reference screening of relevant systematic reviews will also be conducted. Two independent reviewers will screen, quality assess included studies and perform data extraction. JBI tools will be used for quality appraisal, data extraction, synthesis and assessing confidence of summarised findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval is not required for the study since it is based on available published literature. Findings from the review will be disseminated through publication in a peer-reviewed journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>International Prospective Register of Systematic Reviews (PROSPERO) CRD42024605240.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-099088","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T06:57:11Z","timestamp":1762325831000},"page":"e099088","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic communication in heart failure: protocol for a systematic qualitative synthesis of experiences, attitudes and practices"],"prefix":"10.1136","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2739-7875","authenticated-orcid":false,"given":"Christina","family":"Chu","sequence":"first","affiliation":[{"name":"Marie Curie Palliative Care Research Department, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Bloch","sequence":"additional","affiliation":[{"name":"Language and Cognition, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1645-642X","authenticated-orcid":false,"given":"Sarah","family":"Yardley","sequence":"additional","affiliation":[{"name":"Marie Curie Palliative Care Research Department, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"2025120413251893000_15.11.e099088.1","unstructured":"The Health Foundation . Person-centred care made simple. London, UK: The Health Foundation, 2015."},{"key":"2025120413251893000_15.11.e099088.2","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1001\/jama.2019.11533","article-title":"Communication Strategies for Sharing Prognostic Information With Patients","volume":"322","author":"Paladino","year":"2019","journal-title":"JAMA"},{"key":"2025120413251893000_15.11.e099088.3","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1177\/1474515120918355","article-title":"Life and priorities before death: A narrative inquiry of uncertainty and end of life in people with heart failure and their family members","volume":"19","author":"Molzahn","year":"2020","journal-title":"Eur J Cardiovasc Nurs"},{"key":"2025120413251893000_15.11.e099088.4","unstructured":"National Institute for Health and Care Excellence (NICE) . Chronic heart failure in adults: diagnosis and management. 2018."},{"key":"2025120413251893000_15.11.e099088.5","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/cvr\/cvz200","article-title":"Palliative care for people living with heart failure: European Association for Palliative Care Task Force expert position statement","volume":"116","author":"Sobanski","year":"2020","journal-title":"Cardiovasc Res"},{"key":"2025120413251893000_15.11.e099088.6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"2025120413251893000_15.11.e099088.7","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000001063"},{"key":"2025120413251893000_15.11.e099088.8","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp11X549018"},{"key":"2025120413251893000_15.11.e099088.9","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1002\/ehf2.12941","article-title":"Dying to know: prognosis communication in heart failure","volume":"7","author":"Cavanagh","year":"2020","journal-title":"ESC Heart Fail"},{"key":"2025120413251893000_15.11.e099088.10","first-page":"573","article-title":"Population Impact of Heart Failure and the Most Common Forms of Cancer","volume":"3","author":"Stewart","year":"2010","journal-title":"Circ: Cardiovascular Quality and Outcomes"},{"key":"2025120413251893000_15.11.e099088.11","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.822"},{"key":"2025120413251893000_15.11.e099088.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32520-5"},{"key":"2025120413251893000_15.11.e099088.13","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvac013"},{"key":"2025120413251893000_15.11.e099088.14","doi-asserted-by":"crossref","first-page":"441","DOI":"10.11124\/JBIES-22-00107","article-title":"Advance care planning experiences of patients with heart failure and their families: a qualitative systematic review protocol","volume":"21","author":"Higashitsuji","year":"2023","journal-title":"JBI Evid Synth"},{"key":"2025120413251893000_15.11.e099088.15","doi-asserted-by":"crossref","first-page":"3431","DOI":"10.1016\/j.pec.2022.08.011","article-title":"Communication regarding the deactivation of implantable cardioverter-defibrillators: A scoping review and narrative summary of current interventions","volume":"105","author":"Callaghan","year":"2022","journal-title":"Patient Educ Couns"},{"key":"2025120413251893000_15.11.e099088.16","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2021-002894"},{"key":"2025120413251893000_15.11.e099088.17","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/ehf2.14831","article-title":"The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review","volume":"12","author":"Murray","year":"2025","journal-title":"ESC Heart Fail"},{"key":"2025120413251893000_15.11.e099088.18","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000062"},{"key":"2025120413251893000_15.11.e099088.19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2011.05636.x"},{"key":"2025120413251893000_15.11.e099088.20","doi-asserted-by":"crossref","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"2025120413251893000_15.11.e099088.21","doi-asserted-by":"crossref","unstructured":"Lockwood C , Porritt K , Munn Z , et al . 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