{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:06:08Z","timestamp":1771329968949,"version":"3.50.1"},"reference-count":69,"publisher":"BMJ","issue":"12","license":[{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"unspecified","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Erasmus MC Foundation"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,11,20]]},"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Postictal agitation (PIA) is a common adverse effect following electroconvulsive therapy (ECT). Current pharmacological treatments for PIA have undesirable side effects, and interventions to prevent PIA are unsatisfactory. The aim of this study is to assess the effect of peri-interventional music on PIA for patients undergoing ECT. Additionally, the study will assess the impact of music on pretreatment anxiety and post-treatment cognitive impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This multicentre, open-label, parallel randomised controlled trial (RCT) aims to include 92 patients from two centres in Rotterdam, the Netherlands. Participants will be randomised into two groups: a music intervention group and a control group. The music group listens to recorded music 30\u2009min before and 12\u2009min after each of the first six ECT sessions of the full ECT course, while the control group will receive standard care. The primary outcome is the presence of PIA, measured using the Richmond Agitation-Sedation Scale (RASS). Secondary outcomes include the severity and duration of PIA, pretreatment anxiety, recovery duration, peri-treatment medication requirements, cognitive impairment and depression severity. Data will be analysed according to an intention-to-treat principle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This study protocol has been approved by the Medical Ethical Review Committee of the Erasmus Medical Centre on 28 January 2025 (MEC-2024\u20130467) and subsequently received local approval at Antes Parnassia group. The trial will be carried out following the Declaration of Helsinki principles. Study results will be reported in a peer-reviewed journal according to the Consolidated Standards of Reporting Trials guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial \" xlink:href=\"NCT06817330\">NCT06817330<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-105979","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:08:47Z","timestamp":1771326527000},"page":"e105979","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of peri-interventional music on postictal agitation in electroconvulsive therapy patients (MUSE): protocol for an open-label multicentre randomised controlled trial in the Netherlands"],"prefix":"10.1136","volume":"15","clinical-trial-number":[{"clinical-trial-number":"nct06817330","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct06817330","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-4390","authenticated-orcid":false,"given":"Emilie S","family":"van der Valk Bouman","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Ertman","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel R","family":"Koopmans","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joris J B","family":"van der Vlugt-Molenaar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Antes Parnassia, Maasstad Ziekenhuis, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willemijn T C J","family":"Heijnen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasmijn C","family":"van Groen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Antes Parnassia, Maasstad Ziekenhuis, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan-Wiebe","family":"Korstanje","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom K","family":"Birkenhager","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0122-9929","authenticated-orcid":false,"given":"Markus","family":"Klimek","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"2026010307004730000_15.12.e105979.1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.psc.2016.04.004","article-title":"Adverse Effects of Electroconvulsive Therapy","volume":"39","author":"Andrade","year":"2016","journal-title":"Psychiatr Clin North Am"},{"key":"2026010307004730000_15.12.e105979.2","doi-asserted-by":"publisher","DOI":"10.4097\/kja.20097"},{"key":"2026010307004730000_15.12.e105979.3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/YCT.0000000000001032","article-title":"Prognostic Factors and Incidence for Postictal Agitation After Electroconvulsive Therapy: A Systematic Review and Meta-analysis","volume":"41","author":"Ertman","year":"2025","journal-title":"J ECT"},{"key":"2026010307004730000_15.12.e105979.4","first-page":"144","article-title":"Clinical Characteristics of Inpatients Undergoing Electroconvulsive Therapy (Ect) in a University Hospital, Thailand","volume":"17","author":"Pitidhammabhorn","year":"2016","journal-title":"Asean J Psychiatr"},{"key":"2026010307004730000_15.12.e105979.5","doi-asserted-by":"crossref","unstructured":"Feenstra TC , Blake Y , Hoogendoorn AW , et al . Pharmacological prevention of postictal agitation after electroconvulsive therapy-A systematic review and meta-analysis. Front Psychiatry 2023;14. doi:10.3389\/fpsyt.2023.1170931","DOI":"10.3389\/fpsyt.2023.1170931"},{"key":"2026010307004730000_15.12.e105979.6","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1176\/ajp.140.10.1367","article-title":"Postictal excitement following bilateral and right-unilateral ECT","volume":"140","author":"Sackeim","year":"1983","journal-title":"AJP"},{"key":"2026010307004730000_15.12.e105979.7","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.152.7.995"},{"key":"2026010307004730000_15.12.e105979.8","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200303000-00008"},{"key":"2026010307004730000_15.12.e105979.9","doi-asserted-by":"crossref","unstructured":"Biazar G , Khoshrang H , Emir Alavi C , et al . Electroconvulsive Therapy-Related Anxiety: A Survey in an Academic Hospital in the North of Iran. Anesth Pain Med 2020;10. doi:10.5812\/aapm.99429","DOI":"10.5812\/aapm.99429"},{"key":"2026010307004730000_15.12.e105979.10","doi-asserted-by":"publisher","DOI":"10.1177\/014107688107400409"},{"key":"2026010307004730000_15.12.e105979.11","doi-asserted-by":"crossref","unstructured":"Obbels J Fau - Verwijk E , Verwijk E Fau - Bouckaert F , Bouckaert F Fau - Sienaert P , et al . ECT-Related Anxiety: A Systematic Review. J ECT 2017;1533\u20134112. doi:10.1097\/YCT.0000000000000383","DOI":"10.1097\/YCT.0000000000000383"},{"key":"2026010307004730000_15.12.e105979.12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.yebeh.2010.06.036","article-title":"Functional neuroimaging in the postictal state","volume":"19","author":"Koepp","year":"2010","journal-title":"Epilepsy Behav"},{"key":"2026010307004730000_15.12.e105979.13","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1176\/appi.ajp.20240738","article-title":"Antipsychotic Drugs: A Concise Review of History, Classification, Indications, Mechanism, Efficacy, Side Effects, Dosing, and Clinical Application","volume":"181","author":"Leucht","year":"2024","journal-title":"AJP"},{"key":"2026010307004730000_15.12.e105979.14","doi-asserted-by":"publisher","DOI":"10.1097\/00124509-200003000-00002"},{"key":"2026010307004730000_15.12.e105979.15","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/YCT.0b013e3182887b5b","article-title":"Postictal agitation after electroconvulsive therapy: incidence, severity, and propofol as a treatment option","volume":"29","author":"Tzabazis","year":"2013","journal-title":"J ECT"},{"key":"2026010307004730000_15.12.e105979.16","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1001\/jamapsychiatry.2017.1670","article-title":"Modern Electroconvulsive Therapy Vastly Improved yet Greatly Underused","volume":"74","author":"Sackeim","year":"2017","journal-title":"Jama Psychiat"},{"key":"2026010307004730000_15.12.e105979.17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5498\/wjp.v9.i1.1","article-title":"Electroconvulsive therapy: 80 years old and still going strong","volume":"9","author":"Gazdag","year":"2019","journal-title":"World J Psychiatry"},{"key":"2026010307004730000_15.12.e105979.18","doi-asserted-by":"publisher","DOI":"10.2174\/138945005774574489"},{"key":"2026010307004730000_15.12.e105979.19","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10853"},{"key":"2026010307004730000_15.12.e105979.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.aorn.2007.09.013"},{"key":"2026010307004730000_15.12.e105979.21","doi-asserted-by":"crossref","unstructured":"Kakar E , Billar RJ , van Rosmalen J , et al . Music intervention to relieve anxiety and pain in adults undergoing cardiac surgery: a systematic review and meta-analysis. Open Heart 2021;8. doi:10.1136\/openhrt-2020-001474","DOI":"10.1136\/openhrt-2020-001474"},{"key":"2026010307004730000_15.12.e105979.22","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1097\/SLA.0000000000003506","article-title":"The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay","volume":"272","author":"Fu","year":"2020","journal-title":"Ann Surg"},{"key":"2026010307004730000_15.12.e105979.23","doi-asserted-by":"crossref","first-page":"568","DOI":"10.3390\/brainsci12050568","article-title":"Music Interventions and Delirium in Adults: A Systematic Literature Review and Meta-Analysis","volume":"12","author":"Golubovic","year":"2022","journal-title":"Brain Sci"},{"key":"2026010307004730000_15.12.e105979.24","doi-asserted-by":"crossref","unstructured":"Kappen PR , Mos MI , Jeekel J , et al . Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial. BMJ Open 2023;13. doi:10.1136\/bmjopen-2022-069957","DOI":"10.1136\/bmjopen-2022-069957"},{"key":"2026010307004730000_15.12.e105979.25","doi-asserted-by":"crossref","unstructured":"Dirven TL , Fu VX , Becker AS , et al . Effect of perioperative music on delirium after hip fracture operations (MCHOPIN): a multicentre randomised clinical trial in Dutch hospitals. BMJ Open 2025;15. doi:10.1136\/bmjopen-2024-095819","DOI":"10.1136\/bmjopen-2024-095819"},{"key":"2026010307004730000_15.12.e105979.26","doi-asserted-by":"crossref","unstructured":"Cordoba-Silva J , Maya R , Valderrama M , et al . Music therapy with adult burn patients in the intensive care unit: short-term analysis of electrophysiological signals during music-assisted relaxation. Sci Rep 2024;14. doi:10.1038\/s41598-024-73211-3","DOI":"10.1038\/s41598-024-73211-3"},{"key":"2026010307004730000_15.12.e105979.27","doi-asserted-by":"crossref","unstructured":"Erbay Dalli \u00d6 A-O , Bozkurt C-O , Yildirim Y-O . The effectiveness of music interventions on stress response in intensive care patients: A systematic review and meta-analysis. J Clin Nurs 2022;1365\u20132702. doi:10.1111\/jocn.16401","DOI":"10.1111\/jocn.16401"},{"key":"2026010307004730000_15.12.e105979.28","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.jss.2019.06.052","article-title":"The Effect of Perioperative Music on the Stress Response to Surgery: A Meta-analysis","volume":"244","author":"Fu","year":"2019","journal-title":"J Surg Res"},{"key":"2026010307004730000_15.12.e105979.29","doi-asserted-by":"crossref","unstructured":"van der Valk Bouman ES , Becker AS , Schaap J , et al . Perceptions of music listening for pain management: a multi-method study. BMJ Open 2025;15. doi:10.1136\/bmjopen-2024-097233","DOI":"10.1136\/bmjopen-2024-097233"},{"key":"2026010307004730000_15.12.e105979.30","doi-asserted-by":"crossref","first-page":"561","DOI":"10.21608\/jhiph.2007.22541","article-title":"Assessment of Nurses\u2019 Role in Caring for Psychiatric Patients Receiving Electro-Convulsive Therapy","volume":"37","author":"Shalaby","year":"2007","journal-title":"J High Inst Public Health"},{"key":"2026010307004730000_15.12.e105979.31","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60688-1"},{"key":"2026010307004730000_15.12.e105979.32","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-200101000-00005"},{"key":"2026010307004730000_15.12.e105979.33","doi-asserted-by":"crossref","unstructured":"Bieleninik \u0141 , Ettenberger M , Epstein S , et al . n.d. Potential Psychological and Biological Mechanisms Underlying the Effectiveness of Neonatal Music Therapy during Kangaroo Mother Care for Preterm Infants and Their Parents. IJERPH 18:8557. doi:10.3390\/ijerph18168557","DOI":"10.3390\/ijerph18168557"},{"key":"2026010307004730000_15.12.e105979.34","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001452"},{"key":"2026010307004730000_15.12.e105979.35","doi-asserted-by":"crossref","first-page":"857591","DOI":"10.3389\/fmed.2022.857591","article-title":"Music Modulates Autonomic Nervous System Activity in Human Fetuses","volume":"9","author":"Massimello","year":"2022","journal-title":"Front Med"},{"key":"2026010307004730000_15.12.e105979.36","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00005053-194108000-00006","article-title":"MUSIC\u2014AN AID IN MANAGEMENT OF THE PSYCHOTIC PATIENT","volume":"94","author":"Altshuler","year":"1941","journal-title":"J Nerv Ment Dis"},{"key":"2026010307004730000_15.12.e105979.37","unstructured":"Price HG , Mountney V , Knouss R . Selection of music to accompany electroshock therapy. New York: E Podolsky, Music Therapy, 1954."},{"key":"2026010307004730000_15.12.e105979.38","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1176\/ajp.100.7.792","article-title":"FOUR YEARS\u2019 EXPERIENCE WITH MUSIC AS A THERAPEUTIC AGENT AT ELOISE HOSPITAL","volume":"100","author":"Altshuler","year":"1944","journal-title":"AJP"},{"key":"2026010307004730000_15.12.e105979.39","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/YCT.0000000000000315","article-title":"An Investigation of Patient Preferences for Music Played Before Electroconvulsive Therapy","volume":"32","author":"Graff","year":"2016","journal-title":"J ECT"},{"key":"2026010307004730000_15.12.e105979.40","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/YCT.0000000000000866","article-title":"Severe Postictal Confusion After Electroconvulsive Therapy: A Retrospective Study","volume":"39","author":"Schuur","year":"2023","journal-title":"J ECT"},{"key":"2026010307004730000_15.12.e105979.41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123090","article-title":"Efficacy of Non-Pharmacological Interventions to Prevent and Treat Delirium in Older Patients: A Systematic Overview. The SENATOR project ONTOP Series","volume":"10","author":"Abraha","year":"2015","journal-title":"PLoS ONE"},{"key":"2026010307004730000_15.12.e105979.42","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.2147\/CIA.S201323","article-title":"Prevention of postoperative delirium in elderly patients planned for elective surgery: systematic review and meta-analysis","volume":"14","author":"Janssen","year":"2019","journal-title":"Clin Interv Aging"},{"key":"2026010307004730000_15.12.e105979.43","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-048270","article-title":"Music to prevent deliriUm during neuroSurgerY (MUSYC) Clinical trial: a study protocol for a randomised controlled trial","volume":"11","author":"Kappen","year":"2021","journal-title":"BMJ Open"},{"key":"2026010307004730000_15.12.e105979.44","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.h2925","article-title":"Cluster randomised trials with repeated cross sections: alternatives to parallel group designs","volume":"350","author":"Hooper","year":"2015","journal-title":"BMJ"},{"key":"2026010307004730000_15.12.e105979.45","doi-asserted-by":"publisher","DOI":"10.1002\/sim.7028"},{"key":"2026010307004730000_15.12.e105979.46","doi-asserted-by":"crossref","unstructured":"Taipale M , Peltola H-R , Saarikallio S , et al . Music Listening for Self-Management of Anxiety: A Qualitative Survey. Music & Science 2024;7. doi:10.1177\/20592043241264424","DOI":"10.1177\/20592043241264424"},{"key":"2026010307004730000_15.12.e105979.47","doi-asserted-by":"crossref","unstructured":"Wilkins RW , Hodges DA , Laurienti PJ , et al . Network science and the effects of music preference on functional brain connectivity: from Beethoven to Eminem. Sci Rep 2014;4. doi:10.1038\/srep06130","DOI":"10.1038\/srep06130"},{"key":"2026010307004730000_15.12.e105979.48","doi-asserted-by":"publisher","DOI":"10.1037\/a0022406"},{"key":"2026010307004730000_15.12.e105979.49","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1017\/S0033291719001570","article-title":"Dissecting the impact of depression on decision-making","volume":"50","author":"Lawlor","year":"2020","journal-title":"Psychol Med"},{"key":"2026010307004730000_15.12.e105979.50","unstructured":"Safe listening devices and systems: a WHO-ITU standard. Geneva World Health Organization and International Telecommunication Union; 2019."},{"key":"2026010307004730000_15.12.e105979.51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2009.01969.x"},{"key":"2026010307004730000_15.12.e105979.52","doi-asserted-by":"publisher","DOI":"10.1111\/j.1466-7657.2011.00888.x"},{"key":"2026010307004730000_15.12.e105979.53","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2107138"},{"key":"2026010307004730000_15.12.e105979.54","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1001\/jama.289.22.2983","article-title":"Monitoring sedation status over time in ICU patients - Reliability and validity of the Richmond Agitation-Sedation Scale (RASS)","volume":"289","author":"Ely","year":"2003","journal-title":"Jama-J Am Med Assoc"},{"key":"2026010307004730000_15.12.e105979.55","doi-asserted-by":"crossref","unstructured":"Fuchita M , Pattee J , Le D , et al . n.d. Inter-rater Agreement of Richmond Agitation Sedation Scale Assessments in Adult Patients Receiving Mechanical Ventilation in the ICU: A Cross-Sectional Study. Critical Care Explorations 7:e1302. doi:10.1097\/CCE.0000000000001302","DOI":"10.1097\/CCE.0000000000001302"},{"key":"2026010307004730000_15.12.e105979.56","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.psym.2013.03.004","article-title":"Predictors of electroconvulsive therapy postictal delirium","volume":"55","author":"Reti","year":"2014","journal-title":"Psychosomatics"},{"key":"2026010307004730000_15.12.e105979.57","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2014.06.004"},{"key":"2026010307004730000_15.12.e105979.58","first-page":"1389","article-title":"Validation of visual analogue scale for anxiety (VAS-A) in preanesthesia evaluation","volume":"79","author":"Facco","year":"2013","journal-title":"Minerva Anestesiol"},{"key":"2026010307004730000_15.12.e105979.59","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.psychres.2017.11.022","article-title":"Usefulness of the Montreal Cognitive Assessment (MoCA) to monitor cognitive impairments in depressed patients receiving electroconvulsive therapy","volume":"259","author":"Moirand","year":"2018","journal-title":"Psychiatry Res"},{"key":"2026010307004730000_15.12.e105979.60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"2026010307004730000_15.12.e105979.61","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1080\/09638288.2023.2191015","article-title":"Reliability and validity of the telephone-based version of the Montgomery-Asberg depression rating scale for assessing depression in individuals with primary brain tumour","volume":"46","author":"Harris","year":"2024","journal-title":"Disabil Rehabil"},{"key":"2026010307004730000_15.12.e105979.62","doi-asserted-by":"publisher","DOI":"10.1177\/1073191108320415"},{"key":"2026010307004730000_15.12.e105979.63","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e318098614e"},{"key":"2026010307004730000_15.12.e105979.64","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2006.04.008"},{"key":"2026010307004730000_15.12.e105979.65","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.jad.2017.09.042","article-title":"Translating the HAM-D into the MADRS and vice versa with equipercentile linking","volume":"226","author":"Leucht","year":"2018","journal-title":"J Affect Disord"},{"key":"2026010307004730000_15.12.e105979.66","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2021-049706","article-title":"Effect of music on clinical outcome after hip fracture operations (MCHOPIN): study protocol of a multicentre randomised controlled trial","volume":"11","author":"Fu","year":"2021","journal-title":"BMJ Open"},{"key":"2026010307004730000_15.12.e105979.67","unstructured":"SPIRIT (standard protocol items: recommendations for interventional trials). 2023. Available: https:\/\/www.spirit-statement.org"},{"key":"2026010307004730000_15.12.e105979.68","unstructured":"CONSORT 2010 statement. 2023. Available: https:\/\/www.equator-network.org\/reporting-guidelines\/consort"},{"key":"2026010307004730000_15.12.e105979.69","doi-asserted-by":"publisher","DOI":"10.7326\/M17-0046"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2025-105979","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:08:54Z","timestamp":1771326534000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2025-105979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":69,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,10]]},"published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1136\/bmjopen-2025-105979"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2025-105979","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}