{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T10:37:34Z","timestamp":1793270254585,"version":"4.5.0"},"reference-count":30,"publisher":"BMJ","issue":"9","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"unspecified","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001580"],"award-info":[{"award-number":["82001580"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,8,19]]},"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study assessed the knowledge, attitude and practice (KAP) of pregnant women in Chongqing, China, regarding pre-eclampsia and examined their inter-relationships.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>A cross-sectional survey was conducted using validated questionnaires.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>The study was conducted between May 2023 and August 2023 in Chongqing, China.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>A total of 427 pregnant women were included, with 68.15% aged \u226430 years and a mean pregnancy duration of 238.18\u00b145.01\u2009days.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Interventions<\/jats:title>\n                  <jats:p>This was an observational study, and interventions were applied.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Primary and secondary outcome measures<\/jats:title>\n                  <jats:p>The primary outcomes were the KAP scores (knowledge: 0\u201340; attitude: 12\u201360 and practice: 10\u201350). The correlations and structural equation modelling (SEM) analyses were conducted to explore the relationships among KAP.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Mean scores were 22.19\u00b112.17 (knowledge), 46.38\u00b16.14 (attitude) and 41.96\u00b15.96 (practice). Knowledge positively correlated with attitude (r=0.586, p&lt;0.001) and practice (r=0.387, p&lt;0.001). Attitude correlated with practice (r=0.593, p&lt;0.001). SEM showed knowledge directly influenced attitude (\u03b2=0.716, p&lt;0.001), while attitude directly affected practice (\u03b2=0.444, p&lt;0.001). Knowledge indirectly impacted practice via attitude (\u03b2=0.151, p=0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Pregnant women exhibited inadequate knowledge and a suboptimal attitude but a proactive practice. Targeted interventions to improve knowledge and attitudes are recommended for better clinical outcomes, particularly in regions where few such studies have been conducted.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-106259","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T04:40:19Z","timestamp":1757652019000},"page":"e106259","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Knowledge, attitude and practice of pregnant women towards pre-eclampsia in Chongqing, China"],"prefix":"10.1136","volume":"15","author":[{"given":"Dayan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Banan Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, People\u2019s Hospital of Chongqing Banan District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women and Children\u2019s Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, Chongqing Health Center for Women and Children, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Banan Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, People\u2019s Hospital of Chongqing Banan District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Banan Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, People\u2019s Hospital of Chongqing Banan District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Banan Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, People\u2019s Hospital of Chongqing Banan District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4906-3378","authenticated-orcid":false,"given":"Min","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Banan Hospital of Chongqing Medical University, Chongqing, China"},{"name":"Department of Obstetrics, People\u2019s Hospital of Chongqing Banan District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"2025091121401239000_15.9.e106259.1","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.i1753","article-title":"Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies","volume":"353","author":"Bartsch","year":"2016","journal-title":"BMJ"},{"key":"2025091121401239000_15.9.e106259.2","doi-asserted-by":"crossref","DOI":"10.1186\/s12913-023-09170-8","article-title":"Oral health providers\u2019 views of oral health promotion in Jazan, Saudi Arabia: a qualitative study","volume":"23","author":"Shubayr","year":"2023","journal-title":"BMC Health Serv Res"},{"key":"2025091121401239000_15.9.e106259.3","first-page":"619","article-title":"Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome","volume":"16","author":"Chen","year":"2018","journal-title":"Exp Ther Med"},{"key":"2025091121401239000_15.9.e106259.4","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/4154010","article-title":"Resveratrol Supplementation Prevents Hypertension in Hypertensive Pregnant Rats by Increasing Sodium Excretion and Serum Nitric Oxide Level","volume":"2020","author":"Jia","year":"2020","journal-title":"Int J Hypertens"},{"key":"2025091121401239000_15.9.e106259.5","first-page":"3129","article-title":"Correlation of miR-21 and BNP with pregnancy-induced hypertension complicated with heart failure and the diagnostic value","volume":"17","author":"Kan","year":"2019","journal-title":"Exp Ther Med"},{"key":"2025091121401239000_15.9.e106259.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb11582.x"},{"key":"2025091121401239000_15.9.e106259.7","doi-asserted-by":"crossref","unstructured":"Koni A , Taha S , Daifallah A , et al . 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