{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:48:07Z","timestamp":1782492487334,"version":"3.54.5"},"reference-count":18,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"unspecified","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2025,11,28]]},"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Improving neonatal health\u2014including growth, weight gain, neurodevelopment and parent\u2013infant bonding\u2014relies heavily on active parental involvement in neonatal care. Family-centred care models emphasise parental participation, which has been associated with improved physiological stability in infants, reduced parental stress and enhanced emotional bonding. This systematic review aims to synthesise existing evidence on the benefits of parental involvement in neonatal care, highlight best practices and identify gaps requiring further research. A rigorous methodology has been outlined to ensure the reliability and transparency of the review process.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>A comprehensive search strategy will be implemented across major databases, including PubMed, MEDLINE, Scopus and Web of Science, supplemented by manual searches. The review will include randomised controlled trials published between 2000 and January 2025. Studies will be screened according to predefined inclusion criteria, and outcomes of interest will include neonatal growth, weight gain, neurodevelopmental outcomes and parent\u2013infant bonding. Two independent reviewers will perform study selection, data extraction and risk-of-bias assessment, with discrepancies resolved by a third reviewer. Data from included studies will be synthesised using both qualitative and quantitative approaches. If studies are sufficiently homogeneous in design, interventions and outcomes, a meta-analysis will be conducted using appropriate effect measures (eg, mean difference or standardised mean difference for continuous outcomes, and risk ratios for dichotomous outcomes).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>As no primary data will be collected, ethical approval is not required. The findings will be presented at relevant conferences and published in a peer-reviewed journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD420251000485.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-106452","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T12:55:22Z","timestamp":1767617722000},"page":"e106452","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of parental involvement on neonatal growth, neurodevelopmental outcome, parental bonding in neonatal care: a systematic review protocol"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2926-5609","authenticated-orcid":false,"given":"Sharath","family":"Hullumani","sequence":"first","affiliation":[{"name":"Vice Dean (R&D), Datta Meghe Institute of Higher Education and Research Deemed to be University, Wardha, Maharashtra, India"},{"name":"Paedaitrics and Neonatal Sciences, Ravi Nair Physiotherapy College, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irshad","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research Deemed to be University, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghuveer","family":"Raghumahanti","sequence":"additional","affiliation":[{"name":"Neuro Physiotherapy, Datta Meghe Institute of Higher Education and Research Deemed to be University, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"2026062609051388000_16.1.e106452.1","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2022-057092O","article-title":"Family Involvement in the Routine Care of Hospitalized Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis","volume":"150","author":"North","year":"2022","journal-title":"Pediatrics"},{"key":"2026062609051388000_16.1.e106452.2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.aucc.2018.10.007","article-title":"Effects of family-centred care interventions on preterm infants and parents in neonatal intensive care units: A systematic review and meta-analysis of randomised controlled trials","volume":"32","author":"Ding","year":"2019","journal-title":"Aust Crit Care"},{"key":"2026062609051388000_16.1.e106452.3","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2022.987228","article-title":"Parental participation in the care of hospitalized neonates in low- and middle-income countries: A systematic review and meta-analysis","volume":"10","author":"Reiter","year":"2022","journal-title":"Front Pediatr"},{"key":"2026062609051388000_16.1.e106452.4","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S2352-4642(18)30039-7","article-title":"FICare Study Group and FICare Parent Advisory Board. Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial","volume":"2","author":"O\u2019Brien","year":"2018","journal-title":"Lancet Child Adolesc Health"},{"key":"2026062609051388000_16.1.e106452.5","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/s13643-025-02988-9","article-title":"Effect of Vojta technique on improvement in respiratory function and neuromuscular impairment in infants with preterm: a systematic review protocol","volume":"14","author":"Hullumani","year":"2025","journal-title":"Syst Rev"},{"key":"2026062609051388000_16.1.e106452.6","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1186\/1471-2393-13-S1-S10","article-title":"Key components of early intervention programs for preterm infants and their parents: a systematic review and meta-analysis","volume":"13 Suppl 1","author":"Benzies","year":"2013","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026062609051388000_16.1.e106452.7","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2010.10.004"},{"key":"2026062609051388000_16.1.e106452.8","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1038\/sj.jp.7211840","article-title":"Impact of a family-centered care initiative on NICU care, staff and families","volume":"27 Suppl 2","author":"Cooper","year":"2007","journal-title":"J Perinatol"},{"key":"2026062609051388000_16.1.e106452.9","doi-asserted-by":"publisher","DOI":"10.1067\/mhl.2001.110625"},{"key":"2026062609051388000_16.1.e106452.10","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2580"},{"key":"2026062609051388000_16.1.e106452.11","doi-asserted-by":"publisher","DOI":"10.1136\/ebn.10.2.41"},{"key":"2026062609051388000_16.1.e106452.12","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2025-266598","article-title":"Post-discharge infant care in respiratory distress syndrome: a maternal perspective over 6 months","volume":"18","author":"Hullumani","year":"2025","journal-title":"BMJ Case Rep"},{"key":"2026062609051388000_16.1.e106452.13","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jogn.2019.05.001","article-title":"Integrative Review of Parents\u2019 Perspectives of the Nursing Role in Neonatal Family-Centered Care","volume":"48","author":"Reid","year":"2019","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"2026062609051388000_16.1.e106452.14","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1177\/0193945916683679","article-title":"Perceived Needs of Parents of Premature Infants in NICU","volume":"40","author":"Wang","year":"2018","journal-title":"West J Nurs Res"},{"key":"2026062609051388000_16.1.e106452.15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13052-017-0352-1","article-title":"Supporting parents in taking care of their infants admitted to a neonatal intensive care unit: a prospective cohort pilot study","volume":"43","author":"De Bernardo","year":"2017","journal-title":"Ital J Pediatr"},{"key":"2026062609051388000_16.1.e106452.16","article-title":"Nurses\u2019 strategies to provide emotional and practical support to the mothers of preterm infants in the neonatal intensive care unit: A systematic review and meta-analysis","volume":"18","author":"Maleki","year":"2022","journal-title":"Womens Health"},{"key":"2026062609051388000_16.1.e106452.17","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2025-100971","article-title":"Effect of osteopathic manipulation on pain, disability, range of motion and reposition sense in subjects with postural neck pain: a systematic review protocol","volume":"15","author":"Hullumani","year":"2025","journal-title":"BMJ Open"},{"key":"2026062609051388000_16.1.e106452.18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2025-106452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:05:34Z","timestamp":1782489934000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2025-106452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,5]]},"published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1136\/bmjopen-2025-106452"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2025-106452","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}