{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:52:31Z","timestamp":1782492751181,"version":"3.54.5"},"reference-count":67,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"unspecified","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019998","name":"Suicide Prevention Australia","doi-asserted-by":"publisher","award":["RG00182"],"award-info":[{"award-number":["RG00182"]}],"id":[{"id":"10.13039\/501100019998","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2026,2,23]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Self-injurious thoughts and behaviours (SITBs) represent a critical public and mental health challenge. Adolescents are disproportionately at risk for engaging in SITBs. Intervening early and addressing pathogenic and proximal risk\/vulnerability factors is of critical importance for this vulnerable population. Digital Single-Session Interventions (D-SSIs) offer a promising solution to unmet need for accessible, scalable and engaging care. This pilot study aims to evaluate the acceptability and feasibility of the interventions and clinical trial protocol for Programme LIFT (Little Interventions for Teens), a newly developed suite of D-SSIs targeting emotional regulation, self-criticism, rumination and hopelessness as key risk processes involved in the maintenance of SITBs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>We aim to recruit 216 Australian adolescents aged 15\u201319 years who have experienced SITBs in the past 2\u2009months into an online, 2\u00d72 factorial randomised controlled trial to pilot the acceptability and feasibility of the intervention protocol (D-SSI+28 days of skill practice) and trial procedures, and establish study retention. Random allocation procedures will be used to test factors that may affect adherence to the intervention protocol (primary feasibility outcome), by testing the effect of: (1) intervention assignment method (free choice vs clinician prescribed), and (2) a postintervention brief, supportive phone check-in at 7\u2009days postcompletion of the D-SSI (phone call vs no call). Feasibility and acceptability will be assessed using online surveys at postintervention (T1) and 30 days follow-up (T3), along daily brief assessments of skill practice between T1 and T2 (T2). The trial and its protocol were developed and reported in accordance with the Standard Protocol Items for Interventional Trials checklist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This study is approved by the University of New South Wales Human Research Ethics Committee (HREC#9032). Results will be published in an open access peer-reviewed journal, and key study findings will be shared with participants and stakeholders within 3 months after completion of the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>ACTRN12625000963426.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-112453","type":"journal-article","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T14:35:31Z","timestamp":1772807731000},"page":"e112453","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Program LIFT: protocol for a pilot feasibility factorial randomised controlled trial of digital single-session interventions to address self-harm and suicidal ideation in Australian community-based adolescents"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1806-9087","authenticated-orcid":false,"given":"Amaani H","family":"Hatoum","sequence":"first","affiliation":[{"name":"Black Dog Institute, University of New South Wales, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quincy","family":"Wong","sequence":"additional","affiliation":[{"name":"School of Psychology, Western Sydney University, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zinny","family":"Hunt","sequence":"additional","affiliation":[{"name":"Black Dog Institute, University of New South Wales, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1731-210X","authenticated-orcid":false,"given":"Bridianne","family":"O\u2019Dea","sequence":"additional","affiliation":[{"name":"Flinders University Institute for Mental Health and Wellbeing, Flinders University, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9692-0682","authenticated-orcid":false,"given":"Natasha","family":"Josifovski","sequence":"additional","affiliation":[{"name":"Black Dog Institute, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Gan","sequence":"additional","affiliation":[{"name":"Orygen, Melbourne, Victoria, Australia"},{"name":"Centre for Youth Mental Health, The University of Melbourne, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3741-8075","authenticated-orcid":false,"given":"Michelle","family":"Torok","sequence":"additional","affiliation":[{"name":"Black Dog Institute, University of New South Wales, Randwick, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"2026062609354284000_16.3.e112453.1","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.1007\/s00787-023-02264-y","article-title":"The prevalence of self-injury in adolescence: a systematic review and meta-analysis","volume":"33","author":"Farkas","year":"2024","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"2026062609354284000_16.3.e112453.2","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph16224581","article-title":"Global Lifetime and 12-Month Prevalence of Suicidal Behavior, Deliberate Self-Harm and Non-Suicidal Self-Injury in Children and Adolescents between 1989 and 2018: A Meta-Analysis","volume":"16","author":"Lim","year":"2019","journal-title":"Int J Environ Res Public Health"},{"key":"2026062609354284000_16.3.e112453.3","doi-asserted-by":"publisher","DOI":"10.1177\/070674371405901101"},{"key":"2026062609354284000_16.3.e112453.4","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/sltb.12330","article-title":"The Relationship Between Nonsuicidal Self\u2010Injury Age of Onset and Severity of Self\u2010Harm","volume":"48","author":"Ammerman","year":"2018","journal-title":"Suicide & Life Threat Behav"},{"key":"2026062609354284000_16.3.e112453.5","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1177\/13591045211002609","article-title":"Association between single session service attendance and clinical characteristics in administrative data","volume":"26","author":"Edbrooke-Childs","year":"2021","journal-title":"Clin Child Psychol Psychiatry"},{"key":"2026062609354284000_16.3.e112453.6","doi-asserted-by":"crossref","DOI":"10.2196\/72892","article-title":"Digital Mental Health Interventions for Young People Aged 16-25 Years: Scoping Review","volume":"27","author":"Potts","year":"2025","journal-title":"J Med Internet Res"},{"key":"2026062609354284000_16.3.e112453.7","doi-asserted-by":"crossref","unstructured":"Hoyt MF , Slive A , Young J , et al , eds. 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