{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T16:49:28Z","timestamp":1775580568715,"version":"3.50.1"},"reference-count":24,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"unspecified","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Fujian Provincial Natural Science Foundation of China","award":["2024J011600"],"award-info":[{"award-number":["2024J011600"]}]},{"name":"Startup Fund for scientific research, Fujian Medical University","award":["2023QH1258"],"award-info":[{"award-number":["2023QH1258"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2026,3,26]]},"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Chronic postsurgical pain (CPSP) after hip arthroplasty is a major complication that affects patients\u2019 long-term quality of life. However, reliable tools for the individualised prediction of CPSP risk after hip arthroplasty are lacking. This study aims to develop and validate a nomogram model to predict CPSP risk in patients undergoing hip arthroplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This prospective observational cohort study will consecutively recruit 300 patients undergoing primary hip arthroplasty at the Department of Orthopaedics and Joints, Nanping First Hospital Affiliated with Fujian Medical University. The primary outcome is CPSP assessed at 3 months postoperatively (Visual Analogue Scale score \u22654). Candidate predictor variables have been identified based on literature review and clinical expertise, and include demographics, comorbidities, preoperative pain, psychological status and surgical and perioperative management. The dataset will be randomly split into development and internal validation sets in a 7:3 ratio. We will employ Least Absolute Shrinkage and Selection Operator regression to select variables and will use multivariable logistic regression to build the final prediction model. Internal validation will be performed using bootstrap resampling (1000 repetitions). The model\u2019s discrimination, calibration and clinical utility will be assessed using the C-statistic (area under the curve), calibration plots and decision curve analysis, respectively. The final model will be presented as a nomogram.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study protocol has been approved by the Ethics Committee of Nanping First Hospital (Approval No: NPSY202412034). All participants will provide written informed consent. The results will be submitted for publication in a peer-reviewed academic journal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      ChiCTR2500107193;\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\/showproj.html?proj=282634\">https:\/\/www.chictr.org.cn\/showproj.html?proj=282634<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-114480","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T15:50:29Z","timestamp":1775577029000},"page":"e114480","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of risk factors and development of a predictive nomogram for chronic postsurgical pain after hip arthroplasty: a study protocol in a Chinese tertiary hospital"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2601-5150","authenticated-orcid":false,"given":"Ruping","family":"Ni","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaowen","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenghua","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaorui","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongli","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8093-496X","authenticated-orcid":false,"given":"Zhaochun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9847-4355","authenticated-orcid":false,"given":"Ping","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Management, Nanping First Hospital Affiliated to Fujian Medical University, Nanping, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"2026040708502276000_16.4.e114480.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60457-7"},{"key":"2026040708502276000_16.4.e114480.2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.blo.0000187339.02380.70","article-title":"Editorial: minimally invasive and small-incision joint replacement surgery: what surgeons should consider","volume":"440","author":"McGrory","year":"2005","journal-title":"Clin Orthop Relat Res"},{"key":"2026040708502276000_16.4.e114480.3","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.02441"},{"key":"2026040708502276000_16.4.e114480.4","first-page":"1453","article-title":"Reports and analysis of amount of hip and knee arthroplasty in China from 2011 to 2019","volume":"40","author":"Yanyan","year":"2020","journal-title":"Chinese Journal of Orthopaedics"},{"key":"2026040708502276000_16.4.e114480.5","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00222"},{"key":"2026040708502276000_16.4.e114480.6","unstructured":"Wu S , Qin X . 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