{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:28:55Z","timestamp":1792787335443,"version":"4.5.0"},"reference-count":14,"publisher":"BMJ","issue":"9","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"unspecified","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Shanghai Clinical Research Center for Gynecological Diseases","award":["22MC1940200"],"award-info":[{"award-number":["22MC1940200"]}],"id":[{"id":"https:\/\/ror.org\/057tkkm33","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2705004"],"award-info":[{"award-number":["2022YFC2705004"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2026,9,15]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to explore the developmental experiences and nursing needs of female patients diagnosed with Peutz-Jeghers syndrome (PJS) during childhood, thereby providing references for developing targeted nursing interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Using purposive sampling, face-to-face semistructured interviews were conducted with female patients diagnosed with PJS in childhood. Data were gathered and examined using directed content analysis based on phenomenological research principles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The study was conducted in Shanghai, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>In total, 35 female patients diagnosed with PJS in childhood were interviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three themes and nine subthemes emerged: microsystem (self-perception and social barriers, challenges related to marriage and childbearing, physiological and psychological distress and treatment adherence pressure), mesosystem (inadequate family communication and support, as well as social isolation) and macrosystem (uneven distribution of medical resources, weak social support networks, as well as inadequate policy and insurance coverage).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Female patients with childhood-onset PJS face diverse and complex challenges within their social environments. Healthcare professionals should recognise the physical and psychological impacts of the illness, provide appropriate interventions to address patients\u2019 needs and help maintain ecosystem stability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-114511","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:00:30Z","timestamp":1790614830000},"page":"e114511","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Developmental experiences of female patients diagnosed with Peutz-Jeghers syndrome in childhood: a qualitative study based on the social ecological model in China"],"prefix":"10.1136","volume":"16","author":[{"given":"Hui","family":"Wang","sequence":"first","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beining","family":"An","sequence":"additional","affiliation":[{"name":"Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Xu","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhua","family":"Han","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Li","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwen","family":"Ding","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranran","family":"Chai","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zheng","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinzhu","family":"Tang","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangqin","family":"Jin","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihua","family":"Huang","sequence":"additional","affiliation":[{"name":"Clinical Research Center, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China"},{"name":"Department of Obstetrics and 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