{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:45:47Z","timestamp":1787323547597,"version":"build-2736575974"},"reference-count":43,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"unspecified","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373573"],"award-info":[{"award-number":["82373573"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2026,7,21]]},"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the association between serum 25-hydroxyvitamin D (25-OH-D) levels and mild cognitive impairment (MCI) and further analyse the association between serum 25-OH-D levels and different dimensions of cognitive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tianjin, China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 866 participants aged 65 and above were enrolled in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome<\/jats:title>\n                    <jats:p>MCI was diagnosed based on the revised Petersen diagnostic criteria. Cognitive function was assessed by the Wechsler Adult Intelligence Scale Revised in China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of MCI was 12.0%. Higher serum 25-OH-D levels were significantly associated with lower odds of MCI, as well as with MCI across all subgroups (p&lt;0.05). Serum 25-OH-D levels were significantly and positively associated with full intelligence quotient (FIQ), verbal intelligence quotient (VIQ), information, similarity and vocabulary (p&lt;0.05). The associations between serum 25-OH-D levels and cognitive function did not significantly differ by age, gender or education level, with no statistical evidence of interactive effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher serum 25-OH-D levels were significantly associated with lower odds of MCI. Furthermore, serum 25-OH-D levels were significantly and positively associated with different dimensions of cognitive function, specifically FIQ, VIQ, information, similarity and vocabulary. There was no statistically significant interaction observed between serum 25-OH-D levels and age, gender or education level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2025-115914","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:08:31Z","timestamp":1787321311000},"page":"e115914","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Association between serum 25-hydroxyvitamin D levels and cognitive function among older adults in Tianjin, China: a cross-sectional community-based study"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2560-546X","authenticated-orcid":false,"given":"Ziyan","family":"Lou","sequence":"first","affiliation":[{"name":"Department of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China"},{"name":"Key Laboratory of Prevention and Control of Major Disease 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