{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T12:45:14Z","timestamp":1782909914553,"version":"3.54.5"},"reference-count":33,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"unspecified","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Shanghai Pujiang Program","award":["25PJC075"],"award-info":[{"award-number":["25PJC075"]}]},{"name":"Start-up Research Grant from Shanghai University of Sport","award":["A1-2G01-25-0010-11"],"award-info":[{"award-number":["A1-2G01-25-0010-11"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2026,4,23]]},"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pain experienced during functional activities, referred to as movement-evoked pain (MEP), is a common and disabling symptom in individuals with knee osteoarthritis (KOA). Unlike pain at rest, MEP may better reflect the real-life burden of KOA and is increasingly recognised as a core outcome in musculoskeletal pain trials. However, its clinical utility remains limited by a lack of evidence on its measurement properties. This study aims to evaluate the test-retest reliability and validity of MEP assessments during functional tasks in individuals with KOA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>\n                      This study includes two components: (1) a test-retest reliability assessment conducted over two sessions separated by approximately 7\u2009days and (2) a cross-sectional analysis of convergent validity. We will recruit 62 participants with symptomatic KOA from the local communities. MEP will be assessed using an 11-point Numeric Rating Scale during five standardised functional tasks: 30-Second Chair Stand Test, One-Step Stair Climb Test, 40m Fast-Paced Walk Test, Timed Up and Go Test and Six-Minute Walk Test. Test-retest reliability will be evaluated using intraclass correlation coefficients (ICC\n                      <jats:sub>3,1<\/jats:sub>\n                      ). Convergent validity will be assessed separately for each functional task by calculating correlation coefficients between MEP ratings and the pain subscale of the Knee injury and Osteoarthritis Outcome Score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>This study was approved by the Ethics Committee from Shanghai University of Sport (Ref: 102772025RT193). The study protocol was registered on the Open Science Framework (10.17605\/OSF.IO\/B9N7G). The findings will be disseminated through presentations at national and international scientific conferences and submitted for publication in a peer-reviewed journal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2026-116380","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:00:53Z","timestamp":1779883253000},"page":"e116380","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Test-retest reliability and validity of movement-evoked pain in patients with knee osteoarthritis: a methodological study protocol"],"prefix":"10.1136","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7773-0149","authenticated-orcid":false,"given":"Liming","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, Seventh People\u2019s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongfu","family":"Liu","sequence":"additional","affiliation":[{"name":"Nursing Department, Shanghai Pudong New Area Geriatric Hospital, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishnan","family":"Mani","sequence":"additional","affiliation":[{"name":"Centre for Health, Activity, and Rehabilitation Research (CHARR), School of Physiotherapy, University of Otago, Dunedin, Otago, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy T.H.","family":"Cheung","sequence":"additional","affiliation":[{"name":"Human Movement Laboratory, School of Health Sciences, Western Sydney University, Campbelltown, New South Wales, Australia"},{"name":"Translational Health Research Institute, Western Sydney University, Penrith, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuelong","family":"Cao","sequence":"additional","affiliation":[{"name":"Institute of Specialized Diagnosis and Treatment Technology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Zhongshan Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Institute of Rehabilitation with Integrated Western and Chinese Traditional Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sizhong","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"2026070104551113000_16.5.e116380.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-025-00594-6","article-title":"Osteoarthritis","volume":"11","author":"Tang","year":"2025","journal-title":"Nat Rev Dis Primers"},{"key":"2026070104551113000_16.5.e116380.2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/art.41142","article-title":"2019 American College of Rheumatology\/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee","volume":"72","author":"Kolasinski","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"2026070104551113000_16.5.e116380.3","doi-asserted-by":"crossref","unstructured":"Hawker GA , Mian S , Kendzerska T , et al . 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