{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T13:35:37Z","timestamp":1767792937237,"version":"3.49.0"},"reference-count":31,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"unspecified","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020875","name":"Universit\u00e9 de Versailles Saint-Quentin-en-Yvelines","doi-asserted-by":"publisher","award":["F07REC02N - 20NAAP03"],"award-info":[{"award-number":["F07REC02N - 20NAAP03"]}],"id":[{"id":"10.13039\/501100020875","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Laboratory of Excellence in Integrative Biology of Emerging Infectious Diseases","award":["ANR-10-LABX-62-IBEID"],"award-info":[{"award-number":["ANR-10-LABX-62-IBEID"]}]},{"DOI":"10.13039\/501100021181","name":"Ecoles doctorales, Universit\u00e9 Paris-Saclay","doi-asserted-by":"publisher","award":["Doctoral fellowship"],"award-info":[{"award-number":["Doctoral fellowship"]}],"id":[{"id":"10.13039\/501100021181","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open Resp Res"],"accepted":{"date-parts":[[2025,10,11]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>COVID-19 pandemic had a significant impact on patients with chronic respiratory diseases (CRD) and was associated with an increased risk of severe outcomes. However, long-term burden of COVID-19 and the dynamics on healthcare utilisation of patients with CRD remain largely unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective was to evaluate outcomes and healthcare utilisation trajectories 1 year after hospitalisation for COVID-19 in patients with CRD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were extracted from the French National Health Database (SNDS). All adults with CRD who had a first hospitalisation for symptomatic COVID-19 and discharged alive between March 2020 and January 2021 were included. Postdischarge care trajectories, including any hospitalisations and ambulatory care recorded in the SNDS, over a 1-year period, were analysed using state sequence analysis. Healthcare utilisation patterns between the year prior to and the year following hospitalisation were then compared, and a multinomial logistic regression analysis was performed to identify baseline CRD category associated with trajectory clusters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 40 066 patients with CRD discharged alive, chronic obstructive pulmonary disease was the main CRD followed by asthma, sleep apnoea and interstitial lung disease. Overall, 6913 (17.3%) died at 1 year. Proportion of days alive spent at home without any care decreased from 91.1% to 64.4%. Five distinct clusters of healthcare trajectories were identified: \u2018home\u2019 (52%) with a slight increase in healthcare utilisation, \u2018home with care\u2019 (22%) with a high healthcare utilisation, \u2018extended hospitalisation\u2019 (9.4%) in long-term care or acute care, \u2018early death\u2019 (11%) and \u2018late death\u2019 (5.1%). Asthma was more often associated with the \u2018home\u2019 trajectory, while other CRD categories were more often associated with other clusters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with CRD hospitalised for COVID-19 had heterogeneous 1-year trajectories, characterised by increased healthcare utilisation and risk of death. Asthma was the only CRD category not associated with excess mortality or high healthcare consumption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjresp-2025-003580","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T07:40:24Z","timestamp":1763451624000},"page":"e003580","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["One-year healthcare trajectories after COVID-19 hospitalisation in patients with chronic respiratory diseases: a nationwide study"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1103-1040","authenticated-orcid":false,"given":"Alexandre","family":"Sabat\u00e9-Elabbadi","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Brolon","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Brun-Buisson","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Al Rahmoun","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Guillemot","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"},{"name":"Universit\u00e9 Paris-Saclay, Assistance Publique-H\u00f4pitaux de Paris (AP-HP), Public Health, Medical Information, Clinical Research, Le Kremlin-Bic\u00eatre, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9506-6309","authenticated-orcid":false,"given":"Muriel","family":"Fartoukh","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique \u2013 H\u00f4pitaux de Paris, Service de M\u00e9decine Intensive R\u00e9animation, H\u00f4pital Tenon, Paris, France"},{"name":"Facult\u00e9 de M\u00e9decine de Cr\u00e9teil, Universit\u00e9 Paris Est Cr\u00e9teil, IMRB GRC CARMAS, Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Watier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, Universit\u00e9 de Versailles St Quentin-en-Yvelines (UVSQ), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) 1018, Centre de Recherche en \u00c9pid\u00e9miologie et Sant\u00e9 des Populations (CESP), Anti-infective evasion and pharmacoepidemiology Research Team, Montigny-Le-Bretonneux, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris-Cit\u00e9, Epidemiology and Modelling of Antimicrobials Evasion (EMAE), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"2026010701515530000_12.1.e003580.1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30105-3"},{"key":"2026010701515530000_12.1.e003580.2","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.04474-2020","article-title":"Chronic respiratory diseases are predictors of severe outcome in COVID-19 hospitalised patients: a nationwide study","volume":"58","author":"Beltramo","year":"2021","journal-title":"Eur Respir J"},{"key":"2026010701515530000_12.1.e003580.3","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1513\/AnnalsATS.202311-974OC","article-title":"COVID-19 Severity and 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