{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T13:06:45Z","timestamp":1761311205696,"version":"3.44.0"},"reference-count":50,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open Sport Exerc Med"],"accepted":{"date-parts":[[2016,11,27]]},"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Transient ischaemic attacks (TIAs) are highly prevalent conditions, with at least 46\u2009000 people per year in the UK having a TIA for the first time. TIAs are a warning that the patient is at risk of further vascular events and the 90-day risk of vascular events following a TIA, excluding events within the first week after diagnosis when the risk is highest, can be as high as 18%. Immediate assessment of patients with TIA, either at accident and emergency, general practice and\/or TIA clinics, is therefore required to address secondary prevention and prevent further vascular events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This article addresses the need for optimising secondary prevention in the acute period following a TIA of ischaemic origin to reduce the risk of further vascular events as per recent Cochrane review advice and presents a novel project, Stroke Prevention Rehabilitation Intervention Trial of Exercise (SPRITE), to do this.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>One novel way to tackle vascular risk factors and promote secondary prevention in patients with TIA could be to adapt a cardiac rehabilitation programme for these patients. SPRITE, a feasibility and pilot study (ClinicalTrials.gov Identifier: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT02712385\">NCT02712385<\/jats:ext-link>) funded by the National Institute for Health Research, is attempting to adapt a home-based cardiac rehabilitation programme, \u2018The Healthy Brain Rehabilitation Manual\u2019, for use in the acute period following a TIA. The use of cardiac rehabilitation programmes post-TIA requires further research, particularly within the primary care setting.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjsem-2016-000161","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T21:08:21Z","timestamp":1483736901000},"page":"e000161","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Optimising secondary prevention in the acute period following a TIA of ischaemic origin"],"prefix":"10.1136","volume":"2","clinical-trial-number":[{"clinical-trial-number":"nct02712385","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct02712385","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct02712385","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Neil","family":"Heron","sequence":"first","affiliation":[{"name":"Department of General Practice and Primary Care, Queen\u2019s University, Belfast, UK"},{"name":"Centre for Public Health Research, Queen\u2019s University, Belfast, UK"},{"name":"Centre of Excellence for Public Health Research, Queen\u2019s University, Belfast, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"2025083110561985000_2.1.e000161.1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.192218"},{"key":"2025083110561985000_2.1.e000161.2","doi-asserted-by":"publisher","DOI":"10.1159\/000337236"},{"key":"2025083110561985000_2.1.e000161.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.emc.2012.05.001"},{"key":"2025083110561985000_2.1.e000161.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(84)80074-0"},{"key":"2025083110561985000_2.1.e000161.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67702-1"},{"key":"2025083110561985000_2.1.e000161.6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s11940-012-0204-7","article-title":"Interactions between cardiovascular and cerebrovascular disease","volume":"14","author":"Di Pasquale","year":"2012","journal-title":"Curr Treat Options Neurol"},{"key":"2025083110561985000_2.1.e000161.7","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000090444.87006.CF"},{"key":"2025083110561985000_2.1.e000161.8","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000024"},{"key":"2025083110561985000_2.1.e000161.9","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-10-122"},{"key":"2025083110561985000_2.1.e000161.10","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100007770"},{"key":"2025083110561985000_2.1.e000161.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61448-2"},{"key":"2025083110561985000_2.1.e000161.12","unstructured":"National Institute for Health and Care Excellence (NICE). 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