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Collegiate student-athletes represent an important cohort in this field. As such, the Pac-12 CARE-Affiliated Program (CAP) was formed in 2017 as a regional hub of the Concussion Assessment, Research and Education (CARE) consortium. CAP is multisite, prospective, longitudinal study that aims to improve student-athlete health by identifying factors associated with concussion incidence and recovery and using this knowledge to inform best clinical practices and policy decisions. CAP employed a staggered rollout across the Pac-12, with the first four institutions enrolling in fall 2018. After receiving institutional review board (IRB) approval, these institutions began consenting student-athletes to share clinical concussion and baseline data for research purposes. Athletes completed baseline testing that included a medical questionnaire, concussion history and a battery for clinical concussion assessments. Concussed student-athletes were given the same battery of assessments in addition to full injury and return to play reports. Clinicians at each university worked with a data coordinator to ensure appropriate reporting, and the Pac-12 Concussion Coordinating Unit at the University of Colorado Boulder provided oversight for quality control of the data study wide. During year 1, CAP consented 2181 student-athletes and tracked 140 concussions. All research was conducted with the appropriate IRB approval across the participating Pac-12 institutions. Data security and dissemination are managed by the Presagia Sports Athlete Electronic Health Record software (Montreal, Quebec, Canada) and QuesGen Systems (San Francisco, California, USA).<\/jats:p>","DOI":"10.1136\/bmjsem-2021-001055","type":"journal-article","created":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T13:37:18Z","timestamp":1621431438000},"page":"e001055","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Pac-12 CARE-Affiliated Program: structure, methods and initial results"],"prefix":"10.1136","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1658-3162","authenticated-orcid":false,"given":"Adam D","family":"Bohr","sequence":"first","affiliation":[{"name":"Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doug F","family":"Aukerman","sequence":"additional","affiliation":[{"name":"Sports Medicine, Samaritan Health Services & Oregon State University, Corvallis, Oregon, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly G","family":"Harmon","sequence":"additional","affiliation":[{"name":"Family Medicine and Orthopaedics and Sports Medicine, University of Washington, Seattle, Washington, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell","family":"Romano","sequence":"additional","affiliation":[{"name":"Athletic Medicine, University of Southern California, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa D","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niki","family":"Konstantinides","sequence":"additional","affiliation":[{"name":"Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J","family":"Petron","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamshid","family":"Ghajar","sequence":"additional","affiliation":[{"name":"Neurosurgery, Brain Performance Center, Stanford University, Stanford, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Giza","sequence":"additional","affiliation":[{"name":"Pediatrics and Neurosurgery, University of California, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sourav K","family":"Poddar","sequence":"additional","affiliation":[{"name":"Family Medicine and Orthopedics, University of Colorado School of Medicine, Aurora, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew B","family":"McQueen","sequence":"additional","affiliation":[{"name":"Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,19]]},"reference":[{"key":"2025083112590609000_7.2.e001055.1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.17626"},{"key":"2025083112590609000_7.2.e001055.2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100338"},{"key":"2025083112590609000_7.2.e001055.3","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515599634"},{"key":"2025083112590609000_7.2.e001055.4","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-017-0707-1"},{"key":"2025083112590609000_7.2.e001055.5","doi-asserted-by":"crossref","unstructured":"Echemendia RJ , Meeuwisse W , McCrory P . 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