{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T02:39:10Z","timestamp":1789267150259,"version":"build-2803163510"},"reference-count":31,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Sex Reprod Health"],"accepted":{"date-parts":[[2020,6,14]]},"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This study investigated the role of women\u2019s age, serum anti-M\u00fcllerian hormone (AMH) level and semen parameters in predicting fecundability.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a prospective cohort study on couples attending for preconceptional health check. Occurrence of conception at 1\u2009year after ceasing contraception and time to pregnancy were noted by telephone follow-up. The women\u2019s age, serum AMH level and total motile normal morphology sperm count (TMNC) were compared between those who conceived and those who did not after 1\u2009year; their independent predictive value on conception at 1\u2009year was analysed by logistic regression. Among those conceiving within 1\u2009year, Spearman\u2019s correlations between time to pregnancy and the clinical parameters were studied.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 100 couples analysed, we found younger age of the women (p=0.008), higher serum AMH level (p=0.038) and higher TMNC (p=0.015) in those that conceived within 1\u2009year. Multivariate logistic regression found that women\u2019s age (OR 0.867, 95%\u2009CI 0.761 to 0.988, p=0.032) and TMNC (OR 1.089, 95% 1.001\u20131.185, p=0.047), but not serum AMH level, significantly predicted conception within 1\u2009year. Among those that conceived within 1\u2009year, none of the parameters analysed were correlated with time to pregnancy within 1\u2009year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Women\u2019s age and TNMC are significant independent predictors of conception within 1\u2009year. No parameter was shown to predict the time to pregnancy within 1\u2009year. This finding can aid preconceptional counselling of couples who are planning for pregnancy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjsrh-2020-200639","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T17:23:13Z","timestamp":1595870593000},"page":"279-286","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Women\u2019s age and total motile normal morphology sperm count predict fecundability: a prospective cohort study"],"prefix":"10.1136","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4882-5151","authenticated-orcid":false,"given":"Mei Ting","family":"Lam","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"},{"name":"Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Yau Ma Tei, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7957-7798","authenticated-orcid":false,"given":"Hang Wun Raymond","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"},{"name":"Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Yau Ma Tei, Hong Kong"},{"name":"The Family Planning Association of Hong Kong, Wan Chai, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching Yin Grace","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"},{"name":"The Family Planning Association of Hong Kong, Wan Chai, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Shu Biu","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pak Chung","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest Hung Yu","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong"},{"name":"Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Yau Ma Tei, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,7,27]]},"reference":[{"key":"2025090512163570000_46.4.279.1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dex234"},{"key":"2025090512163570000_46.4.279.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1728-4457.2004.010_1.x"},{"key":"2025090512163570000_46.4.279.3","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del291"},{"key":"2025090512163570000_46.4.279.4","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu003"},{"key":"2025090512163570000_46.4.279.5","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182116bc8"},{"key":"2025090512163570000_46.4.279.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.08.008"},{"key":"2025090512163570000_46.4.279.7","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1080\/09513590.2017.1306848","article-title":"Anti-M\u00fcllerian hormone does not predict time to pregnancy: results of a prospective cohort study","volume":"33","author":"Depmann","year":"2017","journal-title":"Gynecol Endocrinol"},{"key":"2025090512163570000_46.4.279.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2013.10.007"},{"key":"2025090512163570000_46.4.279.9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.14588"},{"key":"2025090512163570000_46.4.279.10","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.rbmo.2018.01.013","article-title":"Investigation of anti-M\u00fcllerian hormone concentrations in relation to natural conception rate and time to pregnancy","volume":"36","author":"Korsholm","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"2025090512163570000_46.4.279.11","doi-asserted-by":"crossref","unstructured":"World Health Organization . 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