{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:49:58Z","timestamp":1756460998666,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DTB"],"published-print":{"date-parts":[[1994,4]]},"abstract":"<jats:p>Neural tube defects such as spina bifida and anencephaly affect about 2000 pregnancies in the UK each year, and 1600 of these end in termination or stillbirth.1 To help prevent these defects women are advised to take supplements of folic acid around the time of conception and in the early weeks of pregnancy.2 In this article we look at the issues surrounding the routine use of folic acid.<\/jats:p>","DOI":"10.1136\/dtb.1994.32431","type":"journal-article","created":{"date-parts":[[2007,10,19]],"date-time":"2007-10-19T11:28:45Z","timestamp":1192793325000},"page":"31-32","source":"Crossref","is-referenced-by-count":4,"title":["Folic acid to prevent neural tube defects"],"prefix":"10.1136","volume":"32","member":"239","published-online":{"date-parts":[[1994,4,1]]},"reference":[{"key":"2025082722081952000_32.4.31.1","unstructured":"Department of Health. Press release 9 November 1993."},{"key":"2025082722081952000_32.4.31.2","unstructured":"Department of Health. Folic Acid and the Prevention of Neural Tube Defects: Report from an Expert Advisory Group London: HMSO 1992."},{"key":"2025082722081952000_32.4.31.3","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1471-0528.1993.tb15306.x","article-title":"Investigation of factors influencing folate status in women who have had a neural tube defect-affected infant","volume":"100","author":"Wild","year":"1993","journal-title":"Br J Obstet Gynaecol"},{"key":"2025082722081952000_32.4.31.4","doi-asserted-by":"crossref","unstructured":"Wald NJ . Folic acid and neural tube defect: the current evidence and implications for prevention Bock G Marsh J . Neural Tube Defects (Ciba Foundation symposium 181) Chichester: Wiley 1994 192\u00e2\u0080\u0093211.","DOI":"10.1002\/9780470514559.ch12"},{"key":"2025082722081952000_32.4.31.5","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90133-A"},{"key":"2025082722081952000_32.4.31.6","unstructured":"Czeizel AE Dud\u00c3\u00a1s I . Prevention of the first occurrence of NTDs by periconceptional vitamin supplementation N Engl J Med."},{"key":"2025082722081952000_32.4.31.7","doi-asserted-by":"crossref","unstructured":"Milunsky A Jick H Jick SS . Multivitamin\/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects J Am Med Ass 262: 2847\u00e2\u0080\u009352.","DOI":"10.1001\/jama.1989.03430200091032"},{"key":"2025082722081952000_32.4.31.8","unstructured":"Committee on Medical Aspects of Food Policy. Dietary Reference Values for Food Energy and Nutrients for the United Kingdom London: HMSO 1991."}],"container-title":["Drug and Therapeutics Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/dtb.1994.32431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:08:29Z","timestamp":1756357709000},"score":1,"resource":{"primary":{"URL":"https:\/\/dtb.bmj.com\/lookup\/doi\/10.1136\/dtb.1994.32431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,4]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1994,4,1]]},"published-print":{"date-parts":[[1994,4]]}},"alternative-id":["10.1136\/dtb.1994.32431"],"URL":"https:\/\/doi.org\/10.1136\/dtb.1994.32431","relation":{},"ISSN":["0012-6543","1755-5248"],"issn-type":[{"type":"print","value":"0012-6543"},{"type":"electronic","value":"1755-5248"}],"subject":[],"published":{"date-parts":[[1994,4]]}}}