{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T05:40:49Z","timestamp":1772948449689,"version":"3.50.1"},"reference-count":29,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Eur J Hosp Pharm"],"accepted":{"date-parts":[[2018,10,9]]},"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1136\/ejhpharm-2018-001680","type":"journal-article","created":{"date-parts":[[2018,11,12]],"date-time":"2018-11-12T12:17:26Z","timestamp":1542025046000},"page":"162-167","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Management of diabetic foot ulcers: a 25% lidocaine topical cream formulation design, physicochemical and microbiological assessments"],"prefix":"10.1136","volume":"27","author":[{"given":"Hassane","family":"Sadou Yay\u00e9","sequence":"first","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"},{"name":"Laboratoire Mat\u00e9riaux et Sant\u00e9, Universit\u00e9 Paris Sud, UFR de Pharmacie, Chatenay-Malabry, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Faucheron","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e9a","family":"Dupont","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadwa","family":"El Kouari","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Fekkar","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Parasitologie et de Mycologie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agn\u00e8s","family":"Bellanger","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Tilleul","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Pharmacie, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pitaux Universitaires Piti\u00e9 Salp\u00eatri\u00e8re \u2013 Charles Foix, Paris, France"},{"name":"UFR de Pharmacie, Pharmacie Clinique, Universit\u00e9 Paris Descartes, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,11,12]]},"reference":[{"key":"2025090222030241000_27.3.162.1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.clinbiomech.2016.06.006","article-title":"Gait parameters of people with diabetes-related neuropathic plantar foot ulcers","volume":"37","author":"Fernando","year":"2016","journal-title":"Clin Biomech"},{"key":"2025090222030241000_27.3.162.2","first-page":"356","article-title":"The impact of callosities on the magnitude and duration of plantar pressure in patients with diabetes mellitus","volume":"28","author":"Pataky","year":"2002","journal-title":"Diabetes Metab"},{"key":"2025090222030241000_27.3.162.3","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.2007.S78"},{"key":"2025090222030241000_27.3.162.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibmb.2010.09.010"},{"key":"2025090222030241000_27.3.162.5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3109\/02652048.2015.1046513","article-title":"Biocompatible lidocaine and prilocaine loaded-nanoemulsion system for enhanced percutaneous absorption: QbD-based optimisation, dermatokinetics and in vivo evaluation","volume":"32","author":"Negi","year":"2015","journal-title":"J Microencapsul"},{"key":"2025090222030241000_27.3.162.6","unstructured":"European Pharmacopeia (Ph. Eur). 9th edn, 2016."},{"key":"2025090222030241000_27.3.162.7","unstructured":"ICH Q2(R1). Validation of analytical procedures: text and methodology, 2005."},{"key":"2025090222030241000_27.3.162.8","unstructured":"European Pharmacopeia. Microbiological examination of non-sterile products: microbial enumeration tests. 9th\u00a0edn, 2016."},{"key":"2025090222030241000_27.3.162.9","unstructured":"European Pharmacopeia. Microbiological examination of non-sterile products: test for specified microorganisms. 9th\u00a0edn, 2016."},{"key":"2025090222030241000_27.3.162.10","unstructured":"European Pharmacopeia. Efficacity of antimicrobial preservation. 9th edn, 2016."},{"key":"2025090222030241000_27.3.162.11","unstructured":"Stokes GG . On the effect of the internal friction of fluids on the motion of pendulum. Cambridge: Pitt Press, 1851."},{"key":"2025090222030241000_27.3.162.12","doi-asserted-by":"crossref","unstructured":"Walstra P , Smulders P . Emulsion formation. In: Binks BP , ed. Modern aspects of emulsion science. Cambridge, UK: Royal Society of Chemistry, 1998.","DOI":"10.1039\/9781847551474-00056"},{"key":"2025090222030241000_27.3.162.13","doi-asserted-by":"crossref","first-page":"7131","DOI":"10.1021\/la0000419","article-title":"Coalescence in highly concentrated coarse emulsions","volume":"16","author":"van Aken","year":"2000","journal-title":"Langmuir"},{"key":"2025090222030241000_27.3.162.14","first-page":"89","article-title":"Formulation d\u2019un gel de lidoca\u00efne pour soins douloureux","volume":"17","author":"Vergely","year":"1998","journal-title":"Journal de Pharmacie clinique"},{"key":"2025090222030241000_27.3.162.15","unstructured":"Emma Hitt P . FDA approves new lidocaine formulation for topical pain relief. Medscape 2012."},{"key":"2025090222030241000_27.3.162.16","first-page":"696","article-title":"[Determination of lidocaine and its metabolites in human plasma by liquid chromatography in combination with tandem mass spectrometry]","volume":"41","author":"Xiang","year":"2010","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"key":"2025090222030241000_27.3.162.17","doi-asserted-by":"crossref","unstructured":"Sena LC , Matos HR , D\u00f3rea HS , et al . Dispersive liquid-liquid microextraction based on solidification of floating organic drop and high-performance liquid chromatography to the analysis of cocaine\u2019s major adulterants in human urine. Toxicology 2017;376.doi:10.1016\/j.tox.2016.04.008","DOI":"10.1016\/j.tox.2016.04.008"},{"key":"2025090222030241000_27.3.162.18","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0378-4347(97)00235-1","article-title":"Determination of diazolidinyl urea in a topical cream by high-performance liquid chromatography","volume":"696","author":"Williams","year":"1997","journal-title":"J Chromatogr B Biomed Sci Appl"},{"key":"2025090222030241000_27.3.162.19","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.jchromb.2009.02.032","article-title":"Simultaneous measurement of diazolidinyl urea, urea, and allantoin in cosmetic samples by hydrophilic interaction chromatography","volume":"877","author":"Doi","year":"2009","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"2025090222030241000_27.3.162.20","doi-asserted-by":"publisher","DOI":"10.1007\/BF00412626"},{"key":"2025090222030241000_27.3.162.21","doi-asserted-by":"publisher","DOI":"10.1159\/000231524"},{"key":"2025090222030241000_27.3.162.22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0378-5173(96)04616-9","article-title":"A revised pKa of lidocaine hydrochloride in aqueous solution at 25\u00b0C established by precision conductometry","volume":"141","author":"Sj\u00f6berg","year":"1996","journal-title":"Int J Pharm"},{"key":"2025090222030241000_27.3.162.23","first-page":"377","article-title":"25% lidocaine ointment for diabetic foot pain: from formulation to systemic safety assessment","volume":"33","author":"Natella","year":"2011","journal-title":"Int J Clin Pharm"},{"key":"2025090222030241000_27.3.162.24","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.8.1024"},{"key":"2025090222030241000_27.3.162.25","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198400091-00004"},{"key":"2025090222030241000_27.3.162.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2010.03.014"},{"key":"2025090222030241000_27.3.162.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2006.08.020"},{"key":"2025090222030241000_27.3.162.28","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201210779"},{"key":"2025090222030241000_27.3.162.29","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s002849910030","article-title":"Inhibition of germ tube formation by Candida albicans by local anesthetics: an effect related to ionic channel blockade","volume":"40","author":"Rodrigues","year":"2000","journal-title":"Curr Microbiol"}],"container-title":["European Journal of Hospital Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ejhpharm-2018-001680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T05:03:18Z","timestamp":1756875798000},"score":1,"resource":{"primary":{"URL":"https:\/\/ejhp.bmj.com\/lookup\/doi\/10.1136\/ejhpharm-2018-001680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,12]]},"references-count":29,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,4,23]]},"published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1136\/ejhpharm-2018-001680"],"URL":"https:\/\/doi.org\/10.1136\/ejhpharm-2018-001680","relation":{},"ISSN":["2047-9956","2047-9964"],"issn-type":[{"value":"2047-9956","type":"print"},{"value":"2047-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,12]]}}}