{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T11:21:59Z","timestamp":1779276119937,"version":"3.51.4"},"reference-count":20,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Frontline Gastroenterol"],"accepted":{"date-parts":[[2011,6,22]]},"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>Transfusion-dependent anaemia and portal hypertension are recognised complications of hereditary haemorrhagic telangiectasia (HHT). The anaemia is a result of chronic bleeding from gastrointestinal telangiectasias, which are usually multiple and located throughout the gastrointestinal tract. As a result, treatment with argon plasma coagulation via gastroscopy and or colonoscopy is often insufficient to prevent ongoing blood loss. Portal hypertension in HHT occurs as a result of blood shunting between the hepatic artery and the portal vein within the liver. The somatostatin analogue octreotide has been used as a treatment for bleeding angiodysplasia; however, its possible role as a treatment for diuretic intractable ascites secondary to portal hypertension has not been previously established. The authors report a case that apparently illustrates a dual benefit of long-acting octreotide in the management of both occult bleeding and refractory ascites in a patient with HHT.<\/jats:p>","DOI":"10.1136\/fg.2010.003459","type":"journal-article","created":{"date-parts":[[2011,7,27]],"date-time":"2011-07-27T20:31:46Z","timestamp":1311798706000},"page":"226-229","source":"Crossref","is-referenced-by-count":1,"title":["Two for the price of one: a dual treatment benefit of long-acting octreotide in occult bleeding and diuretic intractable ascites"],"prefix":"10.1136","volume":"2","author":[{"given":"Bee Leng","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Hurley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Hawkes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Alcolado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2011,7,26]]},"reference":[{"key":"2025090708070244000_2.4.226.1","unstructured":"Scottish Inter-collegiate Guidelines Network (SIGN). 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