{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:54:38Z","timestamp":1771332878026,"version":"3.50.1"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Frontline Gastroenterol"],"accepted":{"date-parts":[[2012,10,29]]},"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>There is a rising incidence of several sexually transmitted infections (STIs), many of which can present with proctitis. Causative organisms include <jats:italic>Neisseria gonorrhoeae<\/jats:italic>, <jats:italic>Chlamydia trachomatis<\/jats:italic>, herpes simplex virus, <jats:italic>Treponema pallidum<\/jats:italic> (syphilis), <jats:italic>Giardia lamblia<\/jats:italic> (giardiasis) and <jats:italic>Entamoeba histolytica<\/jats:italic> (amoebiasis). This paper outlines important clinical discriminators and key investigations to distinguish these organisms from non-infective pathology that include inflammatory bowel disease, solitary rectal ulcer syndrome and Beh\u00e7et's syndrome. Management of these infections is described and suggestions are made for successful gastroenterology clinical consultation when an STI is suspected.<\/jats:p>","DOI":"10.1136\/flgastro-2012-100274","type":"journal-article","created":{"date-parts":[[2012,12,5]],"date-time":"2012-12-05T13:52:08Z","timestamp":1354715528000},"page":"32-40","source":"Crossref","is-referenced-by-count":44,"title":["Sexually transmitted infections manifesting as proctitis"],"prefix":"10.1136","volume":"4","author":[{"given":"Chris A","family":"Lamb","sequence":"first","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK"},{"name":"Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth Iris Mary","family":"Lamb","sequence":"additional","affiliation":[{"name":"Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK"},{"name":"Northern Deanery General Practice Vocational Training Scheme, Northern Deanery, North East Strategic Health Authority, Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C","family":"Mansfield","sequence":"additional","affiliation":[{"name":"Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K Nathan","family":"Sankar","sequence":"additional","affiliation":[{"name":"Department of Genitourinary Medicine, Newcastle Primary Care Trust, Newcroft Centre, Newcastle upon Tyne Hospitals Trust, Newcastle upon Tyne, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,12,5]]},"reference":[{"key":"2025090709571088000_4.1.32.1","unstructured":"Health Protection Agency. New data show sexually transmitted infection diagnoses on the rise in England. 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