{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:34:40Z","timestamp":1757619280421,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Frontline Gastroenterol"],"accepted":{"date-parts":[[2016,12,11]]},"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>Achalasia is a rare oesophageal motility disorder predominantly causing dysphagia and regurgitation of food and fluids. Diagnosis is made typically after a combination of tests including endoscopy, barium swallow and oesophageal manometry. The advent of high-resolution manometry has led to the Chicago Classification which divided achalasia into three types. This improved the understanding of presentation, prognosis and might also help tailor therapy. Botulinum toxin has been shown to have good, but short-term efficacy. The predominant treatments include pneumatic balloon dilatation and laparoscopic Heller's myotomy, both of which have similar and durable outcomes, although the success of both reduces with time. Per-oral endoscopic myotomy (POEM) has been shown to be as effective, safe and durable as earlier treatments for achalasia; however, randomised controlled trials are lacking. Indications for POEM are expanding to other hypercontractile motility disorders of the oesophagus.<\/jats:p>","DOI":"10.1136\/flgastro-2016-100770","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T10:35:13Z","timestamp":1486722913000},"page":"143-147","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["POEM and the management of achalasia"],"prefix":"10.1136","volume":"8","author":[{"given":"Matthew","family":"Banks","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, University College London Hospitals, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Sweis","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University College London Hospitals, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,2,10]]},"reference":[{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.1","DOI":"10.1016\/0016-5085(92)91428-7"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.2","DOI":"10.1136\/gut.50.6.765"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.3","DOI":"10.1056\/NEJM199503233321203"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.4","DOI":"10.1097\/SLA.0b013e31818e43ab"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.5","DOI":"10.1016\/S1542-3565(05)00986-9"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.6","DOI":"10.1056\/NEJMoa1010502"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.7","DOI":"10.1136\/gutjnl-2015-310602"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.8","DOI":"10.1097\/SLA.0b013e318159d7dd"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.9","DOI":"10.1055\/s-0029-1244080"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.10","DOI":"10.1016\/j.jamcollsurg.2015.03.057"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.11","DOI":"10.1177\/2050640615581732"},{"key":"2025090709471607000_8.2.143.12","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1055\/s-0042-110397","article-title":"Major perioperative adverse events of peroral endoscopic myotomy: a systematic 5-year analysis","volume":"48","author":"Zhang","year":"2016","journal-title":"Endoscopy"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.13","DOI":"10.1097\/SLA.0000000000000268"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.14","DOI":"10.1007\/s11605-012-2030-3"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.15","DOI":"10.1016\/j.surg.2013.04.042"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.16","DOI":"10.1136\/gutjnl-2014-308649"},{"key":"2025090709471607000_8.2.143.17","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/SLA.0000000000001870","article-title":"Per-oral Endoscopic Myotomy (POEM) after the learning curve: durable long-term results with a low complication rate","volume":"264","author":"Hungness","year":"2016","journal-title":"Ann Surg"},{"key":"2025090709471607000_8.2.143.18","doi-asserted-by":"crossref","first-page":"E195","DOI":"10.1055\/s-0034-1391668","article-title":"Peroral endoscopic myotomy (POEM) vs laparoscopic Heller myotomy (LHM) for the treatment of Type III achalasia in 75 patients: a multicenter comparative study","volume":"3","author":"Kumbhari","year":"2015","journal-title":"Endosc Int Open"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.19","DOI":"10.1016\/j.gie.2010.01.069"},{"doi-asserted-by":"publisher","key":"2025090709471607000_8.2.143.20","DOI":"10.1016\/j.gie.2014.10.011"}],"container-title":["Frontline Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/flgastro-2016-100770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T16:47:24Z","timestamp":1757263644000},"score":1,"resource":{"primary":{"URL":"https:\/\/fg.bmj.com\/lookup\/doi\/10.1136\/flgastro-2016-100770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,10]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,2,10]]},"published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1136\/flgastro-2016-100770"],"URL":"https:\/\/doi.org\/10.1136\/flgastro-2016-100770","relation":{},"ISSN":["2041-4137","2041-4145"],"issn-type":[{"type":"print","value":"2041-4137"},{"type":"electronic","value":"2041-4145"}],"subject":[],"published":{"date-parts":[[2017,2,10]]}}}