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It affects 1%\u201330% of the general population, but is seen in approximately 40% of patients with gastrointestinal conditions including inflammatory bowel disease and cirrhosis. Within this group of patients, it is associated with increased complications and mortality. The pathogenesis of sarcopenia is multifactorial with several risk factors implicated in its development including undernutrition, physical inactivity and coexistent multimorbidity. The SARC-F questionnaire has been developed to screen for patients at risk of sarcopenia, however, this focuses on the functional consequences and will therefore not identify those patients who are early in the progression of sarcopenia. There are several different non-invasive techniques available to assess muscle quantity and quality including; grip strength, dual energy X-ray absorptiometry, CT which can be used together to diagnose sarcopenia. Assessment and correction of malnutrition, particularly protein intake, in those at risk of sarcopenia is important in preventing the development and progression of sarcopenia. There are no specific drugs that are available for the treatment of sarcopenia, however, resistance exercise programmes combined with nutritional interventions show promise. It is important that this common condition is screened for and recognised, with any contributing factors addressed to reduce the risk of its progression.<\/jats:p>","DOI":"10.1136\/flgastro-2019-101348","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T17:16:47Z","timestamp":1579540607000},"page":"53-61","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Getting to grips with sarcopenia: recent advances and practical management for the gastroenterologist"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3134-6648","authenticated-orcid":false,"given":"Thomas William","family":"Hollingworth","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddhartha M","family":"Oke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saint Mark's Hospital, Harrow, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harnish","family":"Patel","sequence":"additional","affiliation":[{"name":"Geriatrics, University Hospital Southampton NHS Foundation Trust, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trevor R","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,1,20]]},"reference":[{"key":"2025090707592172000_12.1.53.1","doi-asserted-by":"crossref","unstructured":"Shakespeare W . 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