{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:30:04Z","timestamp":1757619004659,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Frontline Gastroenterol"],"accepted":{"date-parts":[[2021,9,5]]},"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Chronic gastrointestinal obstruction can precipitate a constellation of symptoms including nausea, vomiting, abdominal distension and pain that negatively impact on health-related quality of life. Decompression via venting gastrostomy can offer symptomatic relief but safety and efficacy data are sparse. This study characterises the diverse venting percutaneous endoscopic gastrostomy (vPEG) cohort at our tertiary referral centre and defines the safety and efficacy of this procedure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients undergoing vPEG between May 2012 and June 2020 were identified from a prospectively maintained database and demographic, procedure-related and mortality data were extracted. Retrospective analysis of case notes provided data on patient symptoms. Last follow-up was May 2021.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>27 patients (median age 63, range 18\u201390 years) underwent vPEG insertion. The majority of vPEGs were for patients with obstruction secondary to locally advanced or metastatic malignancy (n=21\/27, 77.8%). Six procedures were performed for benign disease (n=6\/27, 22.2%). No patients developed the recognised serious complications of bleeding, perforation or peritonitis from vPEG insertion. Symptoms of nausea (p=0.006), vomiting (p&lt;0.001), abdominal distension (p&lt;0.001) and abdominal pain (p=0.002) were improved following vPEG. Pain beyond the expected postprocedural discomfort was associated with a lower number of days survived postprocedure (p=0.026).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>vPEG can be a safe and efficacious palliative intervention for benign and malignant chronic gastrointestinal obstruction. Severe postprocedural pain should be promptly investigated to exclude a potential complication. A defined clinical strategy for assessing and managing these patients would facilitate wider recognition of the benefits of vPEG and improve the safety profile in centres with more limited experience.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/flgastro-2021-101930","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T13:37:11Z","timestamp":1632145031000},"page":"309-315","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Endoscopically placed venting gastrostomy can be a safe and effective palliative intervention in benign and malignant gastrointestinal obstruction"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-186X","authenticated-orcid":false,"given":"Ross J","family":"Porter","sequence":"first","affiliation":[{"name":"Department of Digestive Disorders, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK"},{"name":"Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alastair W","family":"McKinlay","sequence":"additional","affiliation":[{"name":"Department of Digestive Disorders, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma L","family":"Metcalfe","sequence":"additional","affiliation":[{"name":"Department of Digestive Disorders, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,9,20]]},"reference":[{"key":"2025090707564061000_13.4.309.1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2147\/CMAR.S29297","article-title":"Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution","volume":"4","author":"Tuca","year":"2012","journal-title":"Cancer Manag Res"},{"key":"2025090707564061000_13.4.309.2","first-page":"CD002764","article-title":"Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer","volume":"2016","author":"Cousins","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"2025090707564061000_13.4.309.3","unstructured":"NHS Scotland . Scottish palliative care guidelines: symptom control: bowel obstruction, NHS Scotland, last updated 14th December 2020, 2020. https:\/\/www.palliativecareguidelines.scot.nhs.uk\/guidelines\/symptom-control\/bowel-obstruction.aspx"},{"key":"2025090707564061000_13.4.309.4","doi-asserted-by":"crossref","DOI":"10.1186\/1471-230X-7-18","article-title":"Stent versus gastrojejunostomy for the palliation of gastric outlet obstruction: a systematic review","volume":"7","author":"Jeurnink","year":"2007","journal-title":"BMC Gastroenterol"},{"key":"2025090707564061000_13.4.309.5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.4103\/eus.eus_70_19","article-title":"EUS-guided gastroenterostomy for the management of gastric outlet obstruction: a systematic review and meta-analysis","volume":"9","author":"Iqbal","year":"2020","journal-title":"Endosc Ultrasound"},{"key":"2025090707564061000_13.4.309.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.02.028"},{"key":"2025090707564061000_13.4.309.7","doi-asserted-by":"publisher","DOI":"10.1007\/s005200000198"},{"key":"2025090707564061000_13.4.309.8","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/a-1303-7449","article-title":"Endoscopic management of enteral tubes in adult patients - Part 1: Definitions and indications. European Society of Gastrointestinal Endoscopy (ESGE) Guideline","volume":"53","author":"Arvanitakis","year":"2021","journal-title":"Endoscopy"},{"key":"2025090707564061000_13.4.309.9","doi-asserted-by":"publisher","DOI":"10.1136\/flgastro-2019-101306"},{"key":"2025090707564061000_13.4.309.10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1177\/0825859719864915","article-title":"Safety and efficacy of Venting gastrostomy in malignant bowel obstruction: a systematic review","volume":"35","author":"Thampy","year":"2020","journal-title":"J Palliat Care"},{"key":"2025090707564061000_13.4.309.11","unstructured":"NCEPOD \u2018Scoping our practice\u2019 . The 2004 report of the National Confidential enquiry into patient outcome and death. London, 2004."},{"key":"2025090707564061000_13.4.309.12","doi-asserted-by":"publisher","DOI":"10.1177\/082585979601200102"},{"key":"2025090707564061000_13.4.309.13","doi-asserted-by":"crossref","first-page":"bmjspcare-2019-001866","DOI":"10.1136\/bmjspcare-2019-001866","article-title":"Percutaneous venting gastrostomy\/gastrojejunostomy for malignant bowel obstruction: a qualitative study","volume":"9","author":"Singh Curry","year":"2019","journal-title":"BMJ Support Palliat Care"}],"container-title":["Frontline Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/flgastro-2021-101930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T14:57:05Z","timestamp":1757257025000},"score":1,"resource":{"primary":{"URL":"https:\/\/fg.bmj.com\/lookup\/doi\/10.1136\/flgastro-2021-101930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,20]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,6,7]]},"published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1136\/flgastro-2021-101930"],"URL":"https:\/\/doi.org\/10.1136\/flgastro-2021-101930","relation":{},"ISSN":["2041-4137","2041-4145"],"issn-type":[{"type":"print","value":"2041-4137"},{"type":"electronic","value":"2041-4145"}],"subject":[],"published":{"date-parts":[[2021,9,20]]}}}