{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T10:22:41Z","timestamp":1774779761182,"version":"3.50.1"},"reference-count":15,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>A study was performed to determine if the addition of a fortifier to expressed breast milk (EBM) affected gastric emptying in low birthweight infants. Using ultrasonography, the gastric emptying of EBM alone was compared with that containing a fortifier, in a blind, crossover study. Twenty two low birthweight infants were studied: median (range) gestation 31.5 weeks (28-37); birthweight 1495 g (1000-2480 g). The gastric antral cross-sectional area (ACSA) was measured by ultrasonography before each feed and then sequentially after its completion until the ACSA returned to its pre-feed value. The half emptying time was calculated as the time taken for the ACSA to decrease to half the maximum increment. The mean difference (standard error) between half emptying times for EBM alone and for EBM with added fortifier was not significant: 1.48 (4.9) minutes. These data show that fortifying breast milk does not affect gastric emptying and suggests that the practice is unlikely to affect feed tolerance in low birthweight infants.<\/jats:p>","DOI":"10.1136\/fn.74.1.f60","type":"journal-article","created":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T17:55:51Z","timestamp":1225475751000},"page":"F60-F62","source":"Crossref","is-referenced-by-count":55,"title":["Effect of fortifying breast milk on gastric emptying."],"prefix":"10.1136","volume":"74","author":[{"given":"R. J.","family":"McClure","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Newell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1996,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/adc.71.4.376","article-title":"Standing Committee on Nutrition of the British Paediatric Association. Is breast feeding beneficial in the UK?","volume":"71","year":"1994","unstructured":"Standing Committee on Nutrition of the British Paediatric Association. Is breast feeding beneficial in the UK? Arch Dis Child 1994; 71: F376-80.","journal-title":"Arch Dis Child"},{"key":"ref_2","first-page":"125","article-title":"Micronutrients in human milk","volume-title":"milk and milk-based food products","author":"Harzer, G.; Haschke, E.","year":"1989","unstructured":"Harzer G, Haschke E. Micronutrients in human milk. In: Renner E, ed. Micronutrients in milk and milk-based food products. London: Elsevier, 1989: 125-237."},{"key":"ref_3","first-page":"259","article-title":"Factors of human milk influencing the bacterial flora of infant faeces","volume-title":"Composition and physiological properties of human milk","author":"Roberts, A.K.; van Biervliet, J.P.; Harzer, G.","year":"1985","unstructured":"Roberts AK, van Biervliet JP, Harzer G. Factors of human milk influencing the bacterial flora of infant faeces. In: Schaub J, ed. Composition and physiological properties of human milk. London: Elsevier, 1985: 259-69."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0022-3476(83)80302-3","article-title":"Macromineral balances in premature infants fed their own mothers' milk or formula","volume":"102","author":"Atkinson, S.A.; Radde, I.C.; Anderson, G.H.","year":"1983","unstructured":"Atkinson SA, Radde IC, Anderson GH. 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