{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:27:41Z","timestamp":1790778461717,"version":"4.1.0"},"reference-count":19,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"published-print":{"date-parts":[[1997,3,1]]},"abstract":"<jats:sec>\n                  <jats:title>AIMS<\/jats:title>\n                  <jats:p>To determine the prevalence of unilateral neonatal cerebral infarction in infants born at 32 weeks gestation and above; to describe the clinical course, imaging results, and outcome of neonatal cerebral infarction; and to investigate possible aetiology.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec sec-type=\"methods\">\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Twelve cases of unilateral neonatal cerebral infarction were identified from neonatal unit records for the years 1987-93. Each case was matched with two controls.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>All cases of neonatal cerebral infarction occurred in full term infants. The prevalence was around 1 in 4000, and neonatal cerebral infarction was found in 12% of infants presenting with neonatal seizures. Cerebral ultrasound scans failed to demonstrate lesions seen by computed tomography in nine of 12 cases. Cases were more likely than controls to require assisted ventilation for resuscitation at birth (OR 7.0, 95% confidence interval 1.04-53.5), but Apgar scores at 5 minutes were no different. One infant with neonatal cerebral infarction developed a hemiparesis, the other 11 had normal motor development when assessed at 11-60 (median 33) months. None had overt cognitive deficits or persisting seizure disorder.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>Neonatal cerebral infarction is a relatively common cause of neonatal seizures, but the aetiology remains unclear. Parents need to be made aware of possible neurological sequelae, but most cases in this series had a normal outcome.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/fn.76.2.f88","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T11:48:05Z","timestamp":1239191285000},"page":"F88-F93","source":"Crossref","is-referenced-by-count":170,"title":["Unilateral neonatal cerebral infarction in full term infants"],"prefix":"10.1136","volume":"76","author":[{"given":"Javier","family":"Estan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hope","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1997,3,1]]},"reference":[{"key":"2025090515135779000_76.2.F88.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80200-5"},{"key":"2025090515135779000_76.2.F88.2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1984.02140420025010"},{"key":"2025090515135779000_76.2.F88.3","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160506"},{"key":"2025090515135779000_76.2.F88.4","doi-asserted-by":"crossref","first-page":"F67","DOI":"10.1136\/fn.73.2.F67","article-title":"Ischaemic and haemorrhagic brain lesions in newborns with seizures and normal Apgar scores.","volume":"73","author":"Mercuri","year":"1995","journal-title":"Arch Dis Child"},{"key":"2025090515135779000_76.2.F88.5","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(94)00375-N"},{"key":"2025090515135779000_76.2.F88.6","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410170411"},{"key":"2025090515135779000_76.2.F88.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80897-6"},{"key":"2025090515135779000_76.2.F88.8","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(94)90002-7"},{"key":"2025090515135779000_76.2.F88.9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0387-7604(12)80279-8","article-title":"Neonatal cerebral infarction: Symptoms, CT findings and prognosis.","volume":"14","author":"Fujimoto","year":"1992","journal-title":"Brain Dev"},{"key":"2025090515135779000_76.2.F88.10","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1988.02150100080031"},{"key":"2025090515135779000_76.2.F88.11","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(96)88175-8"},{"key":"2025090515135779000_76.2.F88.12","unstructured":"de Vries LS Levene MI (1995) Cerebral ischaemic lesions. in Fetal and neonatal neurology and neurosurgery. eds Levene MI Lilford RJ (Churchill Livingstone, Edinburgh), 2nd edn. pp 379\u2013382."},{"key":"2025090515135779000_76.2.F88.13","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1469-8749.1995.tb11993.x","article-title":"Neonatal stroke involving the middle cerebral artery in term infants: Clinical presentation, EEG and imaging study, and outcome.","volume":"37","author":"Koelfen","year":"1995","journal-title":"Dev Med Child Neurol"},{"key":"2025090515135779000_76.2.F88.14","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0031-3955(16)38368-7","article-title":"Perinatal cerebrovascular disease in the neonate: Parenchymal ischemic lesions in term and preterm infants.","volume":"39","author":"Allan","year":"1992","journal-title":"Ped Clin North Am"},{"key":"2025090515135779000_76.2.F88.15","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1212\/WNL.30.8.889","article-title":"Thrombosis of the middle cerebral artery associated with birth trauma.","volume":"30","author":"Roessmann","year":"1980","journal-title":"Neurology"},{"key":"2025090515135779000_76.2.F88.16","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1980.00500510067013"},{"key":"2025090515135779000_76.2.F88.17","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1985.02140080071035"},{"key":"2025090515135779000_76.2.F88.18","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(91)90043-K"},{"key":"2025090515135779000_76.2.F88.19","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/j.1469-8749.1994.tb11791.x","article-title":"Late magnetic resonance imaging and clinical findings in neonates with unilateral lesions on cranial ultrasound.","volume":"36","author":"Bouza","year":"1994","journal-title":"Dev Med Child Neurol"}],"container-title":["Archives of Disease in Childhood - 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