{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:12:26Z","timestamp":1761765146470,"version":"3.44.0"},"reference-count":27,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"published-print":{"date-parts":[[1999,9,1]]},"abstract":"<jats:sec>\n                  <jats:title>AIM<\/jats:title>\n                  <jats:p>To determine whether neurological deficits are associated with structural anomalies of the brain in very low birthweight (VLBW) infants with subsequent learning disorders but without cerebral palsy, or whether other factors, such as poor early growth, are responsible.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec sec-type=\"methods\">\n                  <jats:title>METHODS<\/jats:title>\n                  <jats:p>Eighty seven VLBW infants and eight term controls who had been examined at school between the ages of 12 and 13 years, had cranial magnetic resonance imaging (MRI) scans at 15\u201317 years of age.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Thirty seven (42.5%) of the VLBW children had abnormalities reported on their scans (two porencephaly, 28 periventricular leucomalacia, 24 ventricular dilatation, and 15 thinning of the corpus callosum). No significant differences in intelligence quotient, motor clumsiness, or frequency of attention deficit \/ hyperactivity disorder were observed between those children with MRI lesions and those with normal scans. Quantitative measurements showed the VLBW infants had smaller brains, and a relatively smaller corpus callosum compared with controls. No association between brain measurements and school performance was observed among the VLBW infants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>The difficulties experienced by VLBW children at school are unlikely to be the result of perinatal brain injury, but they might to be attributable to the effects of poor postnatal growth.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/fn.81.2.f116","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T11:39:47Z","timestamp":1239190787000},"page":"F116-F121","source":"Crossref","is-referenced-by-count":114,"title":["Cranial magnetic resonance imaging and school performance in very low birth weight infants in adolescence"],"prefix":"10.1136","volume":"81","author":[{"given":"R W I","family":"Cooke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L J","family":"Abernethy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1999,9,1]]},"reference":[{"key":"2025090514330882000_81.2.F116.1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.2.204"},{"key":"2025090514330882000_81.2.F116.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.3_Spec_No.286"},{"key":"2025090514330882000_81.2.F116.3","doi-asserted-by":"publisher","DOI":"10.1136\/fn.72.1.F62"},{"key":"2025090514330882000_81.2.F116.4","doi-asserted-by":"publisher","DOI":"10.1136\/adc.62.9.931"},{"key":"2025090514330882000_81.2.F116.5","doi-asserted-by":"publisher","DOI":"10.1136\/adc.67.6.687"},{"key":"2025090514330882000_81.2.F116.6","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1055\/s-2008-1071555","article-title":"Outcome of transient periventricular echodensities in preterm 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stroke.","volume":"154","author":"Mercuri","year":"1995","journal-title":"Eur J Pediatr"},{"key":"2025090514330882000_81.2.F116.10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/002221949102400302","article-title":"Corpus callosum morphology in attention deficit-hyperactivity disorder: morphometric analysis of MRI.","volume":"24","author":"Hynd","year":"1991","journal-title":"J Learn Disab"},{"key":"2025090514330882000_81.2.F116.11","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1176\/ajp.151.12.1791","article-title":"Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder.","volume":"151","author":"Castellanos","year":"1994","journal-title":"Am J 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Neonnatal","year":"1988","journal-title":"Radiology"},{"key":"2025090514330882000_81.2.F116.23","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1542\/peds.78.6.995","article-title":"Periventricular intraparenchymal echodensities in the premature newborn: critical determinant of neurologic outcome.","volume":"78","author":"Guzzetta","year":"1986","journal-title":"Pediatrics"},{"key":"2025090514330882000_81.2.F116.24","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-9091(98)80034-X"},{"key":"2025090514330882000_81.2.F116.25","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.6.957"},{"key":"2025090514330882000_81.2.F116.26","first-page":"971","article-title":"MR features of developing periventricular white matter in preterm infants: evidence of glial cell migration.","volume":"19","author":"Childs","year":"1998","journal-title":"Am J Neuroradiol"},{"key":"2025090514330882000_81.2.F116.27","unstructured":"Maalouf EF, Duggan PJ, Rutherford MA, et al. Magnetic resonance imaging of the brain in extremely preterm infants: normal and abnormal findings from birth to term. J Pediatr (in press)."}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/fn.81.2.F116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T21:33:48Z","timestamp":1757108028000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/fn.81.2.F116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9,1]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1999,9,1]]},"published-print":{"date-parts":[[1999,9,1]]}},"alternative-id":["10.1136\/fn.81.2.F116"],"URL":"https:\/\/doi.org\/10.1136\/fn.81.2.f116","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"type":"print","value":"1359-2998"},{"type":"electronic","value":"1468-2052"}],"subject":[],"published":{"date-parts":[[1999,9,1]]}}}