{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T01:11:53Z","timestamp":1784164313307,"version":"3.55.0"},"reference-count":14,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Dis Child Fetal Neonatal Ed"],"accepted":{"date-parts":[[1999,11,24]]},"published-print":{"date-parts":[[2000,5,1]]},"abstract":"<jats:sec>\n                  <jats:title>BACKGROUND<\/jats:title>\n                  <jats:p>Thyroid function disorders have often been observed in preterm infants after intravenous administration of iodinated contrast medium. The effect on thyroid function depends on the dosage, but the choice of the contrast medium may be equally important, as there are appreciable pharmacological differences between them.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec sec-type=\"methods\">\n                  <jats:title>METHOD<\/jats:title>\n                  <jats:p>Thyroid function was analysed in 20 very low birthweight infants of gestational age less than 30 weeks after injection of iopromide, a monomeric non-ionic iodinated contrast medium. Levels of free thyroxine and thyroid stimulating hormone were compared with those in 26 control infants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>Free thyroxine levels in all study infants ranged from 9.0 to 25.7 pmol\/l (days 14\u201321) and 9.0 to 23.2 pmol\/l (days 35\u201349), and thyroid stimulating hormone levels ranged from 0.13 to 0.26 mU\/l (days 14\u201321) and 0.26 to 11.11 mU\/l (days 35\u201349). These levels were not altered after injection of iopromide.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSION<\/jats:title>\n                  <jats:p>The risk of transient hypothyroidism or hyperthyrotropinaemia may be reduced with the use of iopromide compared with other contrast media.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/fn.82.3.f215","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T06:40:22Z","timestamp":1027752022000},"page":"F215-F217","source":"Crossref","is-referenced-by-count":31,"title":["Thyroid function in very low birthweight infants after intravenous administration of the iodinated contrast medium iopromide"],"prefix":"10.1136","volume":"82","author":[{"given":"J","family":"Dembinski","sequence":"first","affiliation":[{"name":"aDepartment of Neonatology, Children's University Clinic Bonn, Germany, \n\nbDepartment of Neonatology, Children's Clinic, Olgahospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Arpe","sequence":"additional","affiliation":[{"name":"aDepartment of Neonatology, Children's University Clinic Bonn, Germany, \n\nbDepartment of Neonatology, Children's Clinic, Olgahospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Kroll","sequence":"additional","affiliation":[{"name":"aDepartment of Neonatology, Children's University Clinic Bonn, Germany, \n\nbDepartment of Neonatology, Children's Clinic, Olgahospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Hieronimi","sequence":"additional","affiliation":[{"name":"aDepartment of Neonatology, Children's University Clinic Bonn, Germany, \n\nbDepartment of Neonatology, Children's Clinic, Olgahospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Bartmann","sequence":"additional","affiliation":[{"name":"aDepartment of Neonatology, Children's University Clinic Bonn, Germany, \n\nbDepartment of Neonatology, Children's Clinic, Olgahospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2000,5,1]]},"reference":[{"key":"2025090512295956000_82.3.F215.1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1542\/peds.98.4.730","article-title":"Iodine, thyroid function, and very low birth weight infants.","volume":"98","author":"Parravicini","year":"1996","journal-title":"Pediatrics"},{"key":"2025090512295956000_82.3.F215.2","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1651-2227.1995.tb13700.x","article-title":"Thyroid complications, including overt hypothyroidism, related to the use of non-radiopaque silastic catheters for parenteral feeding in 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infants.","volume":"16","author":"Smerdely","year":"1989","journal-title":"Lancet"},{"key":"2025090512295956000_82.3.F215.7","first-page":"537","article-title":"Flow rates of roentgen contrast media of different viscosity in 4.1 Charriere coronary catheters.","volume":"85","author":"Jung","year":"1996","journal-title":"Z Kardiol"},{"key":"2025090512295956000_82.3.F215.8","unstructured":"Fisher DA (1997) Endocrinology of fetal development. in Williams textbook of endocrinology. eds Wilson JD Foster DW Kronenberg HM Larsen PR (WB Saunders, Philadelphia), pp 1273\u20131302."},{"key":"2025090512295956000_82.3.F215.9","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-169-41375"},{"key":"2025090512295956000_82.3.F215.10","first-page":"356","article-title":"Thyroid of the newborn and postnatal iodine overload.","volume":"36","author":"Castaign","year":"1979","journal-title":"Archives Francaises de Pediatrie (Paris)"},{"key":"2025090512295956000_82.3.F215.11","doi-asserted-by":"crossref","first-page":"12675","DOI":"10.1016\/S0021-9258(18)67144-3","article-title":"Transcriptional regulation of thyrotropin subunit genes by thyrotropin-releasing hormone and dopamine in pituitary cell culture.","volume":"261","author":"Shupnik","year":"1986","journal-title":"J Biol Chem"},{"key":"2025090512295956000_82.3.F215.12","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199609000-00024"},{"key":"2025090512295956000_82.3.F215.13","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199422110-00008"},{"key":"2025090512295956000_82.3.F215.14","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"}],"container-title":["Archives of Disease in Childhood - Fetal and Neonatal Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/fn.82.3.F215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T19:30:11Z","timestamp":1757100611000},"score":1,"resource":{"primary":{"URL":"https:\/\/fn.bmj.com\/lookup\/doi\/10.1136\/fn.82.3.F215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5,1]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2000,5,1]]},"published-print":{"date-parts":[[2000,5,1]]}},"alternative-id":["10.1136\/fn.82.3.F215"],"URL":"https:\/\/doi.org\/10.1136\/fn.82.3.f215","relation":{},"ISSN":["1359-2998","1468-2052"],"issn-type":[{"value":"1359-2998","type":"print"},{"value":"1468-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5,1]]}}}