{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T11:07:42Z","timestamp":1775646462850,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Gen. Psychiatry"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Bipolar disorder is associated with high rates of general medical conditions, but few cases of overlap between bipolar disorder and chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) have been reported in the current literature. The following is a case of a 29\u2010year\u2010old patient with a previous major depressive episode comorbid with CLIPPERS. Following glucocorticosteroid therapy, the patient switched to mania\u2010like presentation and was diagnosed with bipolar disorder due to another medical condition. So it is strongly suggested that high\u2010dose corticosteroid pulse therapy could easily induce psychiatric disturbances for patients with previous psychiatric symptoms, and there may be potential links between bipolar disorder and CLIPPERS in the area of inflammation.<\/jats:p>","DOI":"10.1136\/gpsych-2018-000007","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T10:34:38Z","timestamp":1538476478000},"update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Switch from previous major depression comorbid with CLIPPERS to mania\u2010like episode following glucocorticosteroid therapy: a case report"],"prefix":"10.1002","volume":"31","author":[{"given":"Xiaohua","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Psychiatry Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00241-X"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1176\/ps.2006.57.8.1140"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.08.052"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-013-0387-y"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12414"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.12.059"},{"key":"e_1_2_10_8_2","volume-title":"Diagnostic and statistical manual of mental disorder: DSM\u2010IV","author":"American Psychiatry Association (APA)","year":"1994"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq164"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.4065\/81.10.1361"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2017.03.018"}],"container-title":["General Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/gpsych-2018-000007","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1136\/gpsych-2018-000007","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/gpsych-2018-000007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:33:51Z","timestamp":1775644431000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1136\/gpsych-2018-000007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1136\/gpsych-2018-000007"],"URL":"https:\/\/doi.org\/10.1136\/gpsych-2018-000007","archive":["Portico"],"relation":{},"ISSN":["2096-5923","2517-729X"],"issn-type":[{"value":"2096-5923","type":"print"},{"value":"2517-729X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,29]]},"article-number":"e000007"}}