{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T14:35:32Z","timestamp":1776177332036,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1969,10]]},"abstract":"<jats:p>The type and distribution of bacteria in the jejunal juice of patients with a variety of gastrointestinal conditions that might affect the small intestinal flora were examined.<\/jats:p>\n                  <jats:p>Bacterial colonization of the jejunum defined, in this context, as the occurrence of a bile salttolerant flora consisting of both aerobic and anaerobic bacteria qualitatively resembling that of faeces, was observed only in patients with some form of blind loop. Prominent among the bacteria isolated from these colonized juices were non-sporing anaerobic bacteria, most usually Bacteroides, able to hydrolyse bile salts.<\/jats:p>\n                  <jats:p>No simple correlation between the patient's fat excretion and bacterial colonization of the jejunum could be demonstrated.<\/jats:p>","DOI":"10.1136\/gut.10.10.812","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"812-819","source":"Crossref","is-referenced-by-count":110,"title":["Studies on the intestinal flora"],"prefix":"10.1136","volume":"10","author":[{"given":"B. S.","family":"Drasar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margot","family":"Shiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1969,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1172\/JCI104090","article-title":"Studies on lipid metabolism in the small intestine with observations on the role of bile salts","volume":"39","author":"Dawson, A.M.; Isselbacher, K.J.","year":"1960","unstructured":"Dawson, A. M., and Isselbacher, K. J. (1960). Studies on lipid metabolism in the small intestine with observations on the role of bile salts. J. clin. Invest., 39, 730-740.","journal-title":"J. clin. Invest"},{"key":"ref_2","first-page":"94","article-title":"Cultivation of anaerobic intestinal bacteria","author":"Drasar, B.S.","year":"1967","unstructured":"Drasar, B. S. (1967). Cultivation of anaerobic intestinal bacteria. J. Path. Bact., 94,417-427.","journal-title":"J. Path. Bact"},{"key":"ref_3","article-title":"Studies on the intestinal flora","author":"Drasar, B.S.","year":"1968","unstructured":"Drasar, B. S. (1968). Studies on the intestinal flora. Thesis, London University."},{"key":"ref_4","first-page":"1237","article-title":"The deconjugation of bile salts by human intestinal bacteria","volume":"1","author":"Hill, M.J.; Shiner, M.","year":"1966","unstructured":"Hill, M. J., and Shiner, M. (1966). The deconjugation of bile salts by human intestinal bacteria. Lancet, 1, 1237-1238.","journal-title":"Lancet"},{"key":"ref_5","first-page":"71","article-title":"Studies on the intestinal flora. I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydria persons","volume":"56","author":"Hill, M.J.; Shiner, M.; Shiner, M.; McLeod, G.M.","year":"1969","unstructured":"Hill, M. J., and Shiner, M., Shiner, M., and McLeod, G. M. (1969). Studies on the intestinal flora. I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydria persons. Gastroenterology, 56, 71-79.","journal-title":"Gastroenterology"},{"key":"ref_6","first-page":"8","article-title":"Diarrhea and steatorrhea due to a large solitary duodenal diverticulum","author":"Goldstein, F.; Cozzolino, H.J.; Wirts, C.W.","year":"1963","unstructured":"Goldstein, F., Cozzolino, H. J., and Wirts, C. W. (1963). Diarrhea and steatorrhea due to a large solitary duodenal diverticulum. Amer. J. dig. Dis., 8,937-943.","journal-title":"Amer. J. dig. Dis"},{"key":"ref_7","first-page":"\"22","article-title":"Degradation of bile salts by human intestinal bacteria","volume":"9","author":"Hill, M.J.; Drasar, B.S.","year":"1968","unstructured":"Hill, M. J., and Drasar, B. S. (1968). Degradation of bile salts by human intestinal bacteria. Gut, 9, 22-27. van de Kamer, J. H., ten Bokkel Huinink, H., and Weyers, H. A. (1947). Rapid method for determination of fat in feces. J. biol. Chem., 177, 347-355.","journal-title":"Gut; Rapid method for determination of fat in feces"},{"key":"ref_8","first-page":"r","article-title":"Enumeration of the oxygen sensitive bacteria usually present in the intestine of healthy mice","volume":"220","author":"Lee, A.; Gordon, J.; Dubos, R.","year":"1968","unstructured":"Lee, A., Gordon, J., and Dubos, R. (1968). Enumeration of the oxygen sensitive bacteria usually present in the intestine of healthy mice. Nature (Lond.), 220, r 137-1139.","journal-title":"Nature (Lond.)"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0140-6736(63)91328-X","article-title":"A capsule for obtaining sterile samples of gastrointestinal fluids","volume":"1","author":"Shiner, M.","year":"1963","unstructured":"Shiner, M. (1963). A capsule for obtaining sterile samples of gastrointestinal fluids. Lancet, 1, 532-533.","journal-title":"Lancet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0140-6736(68)92888-2","article-title":"Bile-salt deconjugation and steatorrhoea in patients with the stagnantloop syndrome","author":"Tabaqchali, S.; Hatzioannou, J.; Booth, C.C.","year":"1968","unstructured":"Tabaqchali, S., Hatzioannou, J., and Booth, C. C. (1968). Bile-salt deconjugation and steatorrhoea in patients with the stagnantloop syndrome. Lancet, 12-16.","journal-title":"Lancet"},{"key":"ref_11","first-page":"415","article-title":"The correction of postgastrectomy malabsorption following a jejunal interposition operation","author":"Wirts, C.W.; Templeton, J.Y.; Ill, Fineberg; C.; Goldstein, F.","year":"1965","unstructured":"Wirts, C. W., Templeton, J. Y., Ill, Fineberg, C., and Goldstein, F. (1965). The correction of postgastrectomy malabsorption following a jejunal interposition operation. 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