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(1955). Primary peptic ulcerations of the jejunum associated with isletcell tumors of the pancreas. Ann. Surg., 142, 709-728. 5Sircus W (1967). Peptide secreting adenomata and Zollinger-Ellison Syndrome: one of a spectrum of diseases.","journal-title":"Ann. Surg; Peptide secreting adenomata and Zollinger-Ellison Syndrome: one of a spectrum of diseases"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/00000658-196809000-00015","article-title":"A gastric factor in the pathogenesis of the Zollinger-Ellison syndrome","volume":"168","author":"Friesen, S.R.","year":"1968","unstructured":"Friesen, S. R. (1968). A gastric factor in the pathogenesis of the Zollinger-Ellison syndrome. Ann. Surg., 168, 483-501.","journal-title":"Ann. 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(1968)."},{"key":"ref_11","first-page":"895","article-title":"Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin","volume":"2","author":"Murray-Lyon, I.M.; Eddleston, A.L.W.F.; Williams, R.; Brown, M.Hogbin; M., B.; Bennett, A.; Edwards, J.C.; Taylor, K.W.","year":"1968","unstructured":"Murray-Lyon, I. M., Eddleston, A. L. W. F., Williams, R., Brown, M. Hogbin, B. M., Bennett, A., Edwards, J. C., and Taylor, K. W. (1968). Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin. Ibid., 2, 895-898.","journal-title":"Ibid"},{"key":"ref_12","first-page":"1018","article-title":"Hepatoma associated with hypoglycemia, polythemia, and hypercalcemia","volume":"186","author":"Becker, D.J.; Sternberg, M.S.; Kaiser, M.H.","year":"1963","unstructured":"Becker, D. J., Sternberg, M. S., and Kaiser, M. H. (1963). Hepatoma associated with hypoglycemia, polythemia, and hypercalcemia. J. Amer. med. 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Paediat., 63, 895-903.","journal-title":"J. Paediat"},{"key":"ref_15","first-page":"1068","article-title":"Humoral syndromes associated with cancer","volume":"25","author":"Lipsett, M.B.","year":"1965","unstructured":"Lipsett, M. B. (1965). Humoral syndromes associated with cancer. Cancer Res., 25, 1068-1073.","journal-title":"Cancer Res"},{"key":"ref_16","first-page":"\"1045","article-title":"Extraction of a gastrin-like substance from the pancreatic tumour in a case of Zollinger-Ellison syndrome","volume":"1","author":"Gregory, R.A.; Tracy, H.J.; French, J.M.; Sircus, W.","year":"1960","unstructured":"Gregory, R. A., Tracy, H. J., French, J. M., and Sircus, W. (1960). Extraction of a gastrin-like substance from the pancreatic tumour in a case of Zollinger-Ellison syndrome. Lancet, 1, 1045-1048.,Grossman,M. I.,Tracy, H.,Jr.,andBentley,P. H. (1967). Natureofthegastricsecretagogue in Zollinger-Ellison tumours. 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Assay of gastrin by means of its gastric acid stimulating activity. J. Physiol., 198, 613-626.","journal-title":"J. Physiol"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1148\/88.1.32","article-title":"Arteriographic demonstration of pancreatic tumor in the ZollingerEllison syndrome","volume":"88","author":"Clemett, A.R.; Park, W.M.","year":"1967","unstructured":"Clemett, A. R., and Park, W. M. (1967). Arteriographic demonstration of pancreatic tumor in the ZollingerEllison syndrome. Radiology, 88, 32-34.","journal-title":"Radiology"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0140-6736(57)92051-2","article-title":"Islet-cell tumour of the pancreas with peptic ulceration, diarrhoea, hypokalaemia","volume":"2","author":"Priest, W.M.; Alexander, M.K.","year":"1957","unstructured":"Priest, W. M., and Alexander, M. K. (1957). Islet-cell tumour of the pancreas with peptic ulceration, diarrhoea, hypokalaemia. Lancet, 2, 1145-1147.","journal-title":"Lancet"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"58","DOI":"10.7326\/0003-4819-63-1-58","article-title":"Cushing's syndrome due to islet cell carcinoma of the pancreas. Report of two cases: one with elevated 5-hydroxyindole acetic acid","volume":"63","year":"1965","unstructured":"Sayle, B. A., Lang, P. A., Green, W. 0., Jr., Bosworth, W. C., and Gregory R. (1965). Cushing's syndrome due to islet cell carcinoma of the pancreas. Report of two cases: one with elevated 5-hydroxyindole acetic acid. Atnn. intern. Med., 63, 58-68.","journal-title":"Atnn. intern. Med"},{"key":"ref_61","first-page":"\"160","article-title":"Scintillography in the diagnosis of pancreatic disease","volume":"1","author":"Brown, P.W.; Sircus, W.; Smith, A.N.Donaldson; A., A.; Dymock, I.W.; Falconer, C.W.A.; Small, W.P.","year":"1968","unstructured":"Brown, P. W., Sircus, W., Smith, A. N. Donaldson, A. A., Dymock, I. W., Falconer, C. W. A., and Small, W. P. (1968). Scintillography in the diagnosis of pancreatic disease. Lancet, 1, 160-163. \"sMelmed, R. N., Agnew, J. E., and Bouchier, I. A. D. (1968). The normal and abnormal pancreatic scan. Quart. J. Med., 37, 607-624. \" Ellison, E. H., and Wilson, S. D. (1964). The Zollinger-Ellisot syndrome: Re-appraisal and evaluation of 260 registered cases. Ann. Surg., 160, 512-530.","journal-title":"Lancet; The normal and abnormal pancreatic scan"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.10.7.506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T16:46:16Z","timestamp":1765644376000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.10.7.506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,7]]},"references-count":61,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1969,7,1]]},"published-print":{"date-parts":[[1969,7]]}},"alternative-id":["10.1136\/gut.10.7.506"],"URL":"https:\/\/doi.org\/10.1136\/gut.10.7.506","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1969,7]]}}}