{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T14:31:54Z","timestamp":1765636314079,"version":"3.48.0"},"reference-count":4,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1970,1]]},"abstract":"<jats:p>The levels of two peptide hydrolases were studied in intestinal mucosa from normal subjects, patients with untreated coeliac disease, and treated patients. The mucosa from the untreated patients had significantly reduced activity against glycyl-glycine and leucylleucine. No such difference was found for the treated patients and it was concluded that the reduction in peptidase activity was secondary to the mucosal damage.<\/jats:p>","DOI":"10.1136\/gut.11.1.15","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"15-17","source":"Crossref","is-referenced-by-count":30,"title":["Peptide hydrolase activity of human intestinal mucosa in adult coeliac disease"],"prefix":"10.1136","volume":"11","author":[{"given":"Adrian P.","family":"Douglas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J.","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1970,1,1]]},"reference":[{"key":"ref_1","first-page":"7","article-title":"Sprue non tropicale: etiologie et pathogenie","volume":"27","author":"Crabbe, P.","year":"1964","unstructured":"Crabbe, P. (1964). Sprue non tropicale: etiologie et pathogenie. Acta gastroent. belg., 27, 7-18.","journal-title":"Acta gastroent. belg"},{"key":"ref_2","article-title":"Digestion of gluten peptides by normal human jejunal mucosa and by mucosa from patients with adult coeliac disease","author":"Douglas, A.P.; Booth, C.C.","year":"1969","unstructured":"Douglas, A. P., and Booth, C. C. (1969). Digestion of gluten peptides by normal human jejunal mucosa and by mucosa from patients with adult coeliac disease. (Submitted for publication.)"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1177\/003591575604901210","article-title":"Discussion on some problems of steatorrhoea and reduced stature","volume":"49","author":"Frazer, A.C.","year":"1956","unstructured":"Frazer, A. C. (1956). Discussion on some problems of steatorrhoea and reduced stature. Proc. roy. Soc. Med., 49, 1009-1013.","journal-title":"Proc. roy. Soc. Med"},{"key":"ref_4","first-page":"252","article-title":"Gluten induced enteropathy: the effect of partially digested gluten","volume":"2","author":"Frazer, A.C.; Fletcher, R.F.; Ross, C.A.C.; Shaw, B.; Sammons, H.G.; Schneider, R.","year":"1959","unstructured":"Frazer, A. C., Fletcher, R. F., Ross, C. A. C., Shaw, B., Sammons, H. G., and Schneider, R. (1959). Gluten induced enteropathy: the effect of partially digested gluten. Lancet, 2, 252-255.","journal-title":"Lancet"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.11.1.15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T14:30:16Z","timestamp":1765636216000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.11.1.15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1]]},"references-count":4,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1970,1,1]]},"published-print":{"date-parts":[[1970,1]]}},"alternative-id":["10.1136\/gut.11.1.15"],"URL":"https:\/\/doi.org\/10.1136\/gut.11.1.15","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1970,1]]}}}