{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:21:57Z","timestamp":1786371717472,"version":"build-2736575974"},"reference-count":36,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1970,12]]},"abstract":"<jats:p>Two patients with hereditary angioneurotic oedema, a condition characterized by repeated episodes of abdominal pain and oedema, and by an absence of complement-1 esterase inhibitor activity in the plasma are presented in detail. Both underwent multiple surgical procedures before the diagnosis was established. Abdominal pain is often the presenting complaint, and although a complete history will usually lead to the proper diagnosis, cases in which the family history is not clear can present a diagnostic dilemma. Characteristic radiological demonstration of localized intestinal oedema will only be obtained if studies are performed early during the acute attack.<\/jats:p>","DOI":"10.1136\/gut.11.12.983","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"983-988","source":"Crossref","is-referenced-by-count":11,"title":["Hereditary angioneurotic oedema: an unusual case of recurring abdominal pain"],"prefix":"10.1136","volume":"11","author":[{"given":"Edward J.","family":"Feller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard M.","family":"Spiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard A.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1970,12,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1056\/NEJM196504012721301","article-title":"Detection of hereditary angioneurotic edema by demonstration of a reduction in the second component of human complement","volume":"272","author":"Austen, K.F.; Sheffer, A.L.","year":"1965","unstructured":"Austen, K. F., and Sheffer, A. L. (1965). Detection of hereditary angioneurotic edema by demonstration of a reduction in the second component of human complement. New Engl. J. Med., 272 649-656.","journal-title":"New Engl. J. Med"},{"key":"ref_2","first-page":"376","article-title":"Hereditary angioneurotic edema; a remarkable family history","volume":"69","author":"Barnett, A.F.","year":"1948","unstructured":"Barnett, A. F. (1948). Hereditary angioneurotic edema; a remarkable family history. Calif. Med., 69, 376-380.","journal-title":"Calif. Med"},{"key":"ref_3","first-page":"299","article-title":"Concerning the mechanism of complement action. V. The early steps in immune hemolysis","volume":"84","author":"Becker, E.L.","year":"1960","unstructured":"Becker, E. L. (1960). Concerning the mechanism of complement action. V. The early steps in immune hemolysis. J. Immunol., 84, 299-308.","journal-title":"J. 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M., Schreiber, E. 0., and Lovell, R. G. (1949). Hereditary angioneurotic edema with a case report. J. Lab. clin. Med., 34, 524-530.","journal-title":"J. Lab. clin. Med"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"739","DOI":"10.7326\/0003-4819-53-4-739","article-title":"Methyltestosterone therapy for hereditary episodic edema (herediatry angioneurotic edema)","volume":"53","author":"Spaulding, W.B.","year":"1960","unstructured":"Spaulding, W. B. (1960). Methyltestosterone therapy for hereditary episodic edema (herediatry angioneurotic edema). Ann. intern. Med., 53, 739-745.","journal-title":"Ann. intern. Med"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"353","DOI":"10.7326\/0003-4819-71-2-353","article-title":"Angioneurotic edema and deficiency of C'1 esterase inhibitor in a 61 year old woman","volume":"71","author":"Thorvaldsson, S.E.; Sedlack, R.E.; Gleich, G.J.; Ruddy, S.J.","year":"1969","unstructured":"Thorvaldsson, S. E., Sedlack, R. E., Gleich, G. 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