{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:02:47Z","timestamp":1765602167078,"version":"3.48.0"},"reference-count":6,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1971,7]]},"abstract":"<jats:p>A technique for subcutaneous transposition of the spleen in the rat is described. The preparation has been developed as a reliable means of transplenic portal injection.<\/jats:p>\n                  <jats:p>It has been shown that different substances injected into the pulp of the transposed spleen are cleared and not pooled in the organ.<\/jats:p>\n                  <jats:p>The development of porta-systemic venous communications has been demonstrated and their detection radiologically and by isotope techniques is illustrated.<\/jats:p>\n                  <jats:p>It is suggested that the technique outlined in this communication may be of value in the study of the portal circulation, the function of the liver, and in the investigation of drug action.<\/jats:p>\n                  <jats:p>If adequate porta-systemic venous connexions are present the portal vein can be tied above its splenic tributary and the animal will survive. The method offers a simple means of porta-systemic diversion in the rat.<\/jats:p>","DOI":"10.1136\/gut.12.7.585","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"585-591","source":"Crossref","is-referenced-by-count":5,"title":["Portal venous injection in the rat"],"prefix":"10.1136","volume":"12","author":[{"given":"L. H.","family":"Blumgart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. G.","family":"Leach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. S. F.","family":"McLachlan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Seager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. J.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1971,7,1]]},"reference":[{"key":"ref_1","first-page":"7","article-title":"Subcutaneous transposition of the spleen-an experimental studyin therat","volume":"Suppl.","author":"Bengmnark, S.; Borjesson, B.; Olin, T.; Sakuma, S.; Vosmic, J.","year":"1970","unstructured":"Bengmnark, S., Borjesson, B., Olin, T., Sakuma, S., and Vosmic, J. (1970). Subcutaneous transposition of the spleen-an experimental studyin therat. Scand.J. Gastroent.,5, Suppl. 7,175-179.","journal-title":"Scand. J. Gastroent.,5"},{"key":"ref_2","first-page":"186","article-title":"Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal","volume":"12","author":"Higgins, G.M.; Anderson, R.M.","year":"1931","unstructured":"Higgins, G. M., and Anderson, R. M. (1931). Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch. Path., 12, 186.202.","journal-title":"Arch. Path"},{"year":"1971","author":"McLachlan, M.S.F.; Blumgart, L.H.; Roberts, E.E.","key":"ref_3","unstructured":"McLachlan, M. S. F., Blumgart, L. H., and Roberts, E. E. (1971). Spleno-portography in the rat. (Submitted for publication.)"},{"article-title":"Issue","year":"1971","key":"ref_4","unstructured":"The June 1971 Issue"},{"key":"ref_5","article-title":"ISSUE CONTAINS THE FOLLOWING PAPERS","author":"THE, J.U.N.E.","year":"1971","unstructured":"THE JUNE 1971 ISSUE CONTAINS THE FOLLOWING PAPERS"},{"key":"ref_6","article-title":"Notes and activities Copies are still available and may be obtained from the PUBLISHING MANAGER","volume-title":"British Society of Gastroenterology Notes on","year":"books","unstructured":"British Society of Gastroenterology Notes on books Notes and activities Copies are still available and may be obtained from the PUBLISHING MANAGER, BRITISH MEDICAL ASSOCIATION, TAVISTOCK SQUARE, LONDON, WC1H 9JR, price 87TP"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.12.7.585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:59:41Z","timestamp":1765601981000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.12.7.585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,7]]},"references-count":6,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1971,7,1]]},"published-print":{"date-parts":[[1971,7]]}},"alternative-id":["10.1136\/gut.12.7.585"],"URL":"https:\/\/doi.org\/10.1136\/gut.12.7.585","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1971,7]]}}}