{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T08:32:33Z","timestamp":1765614753790,"version":"3.48.0"},"reference-count":19,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1973,5]]},"abstract":"<jats:p>The electrical potential difference across the rectal mucosa in six shunt-operated women was compared with that obtained in 26 normal females. The potential difference was considerably increased in all the patients, whereas the plasma concentrations and the transmural fluxes of sodium, chloride, and potassium were within normal ranges. Based on measurements of plasma renin and plasma aldosterone concentrations in three of the patients, the possibility of secondary hyperaldosteronism could be ruled out.<\/jats:p>","DOI":"10.1136\/gut.14.5.390","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"390-392","source":"Crossref","is-referenced-by-count":2,"title":["Rectal hyperpolarization following intestinal bypass for obesity"],"prefix":"10.1136","volume":"14","author":[{"given":"J.","family":"Rask-Madsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Brix","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. O.","family":"Lund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1973,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1172\/JCI103818","article-title":"The electrical potential difference generated by the large intestine: its relation to electrolyte and water transfer","volume":"34","author":"Cooperstein, T.L.; Brockman, S.K.","year":"1959","unstructured":"Cooperstein, T. L., and Brockman, S. K. (1959). The electrical potential difference generated by the large intestine: its relation to electrolyte and water transfer. J. clin. Invest., 34, 435-442.","journal-title":"J. clin. Invest"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1085\/jgp.43.3.555","article-title":"Na, Cl, and water transport by rat colon","volume":"43","author":"Curran, P.F.; Schwartz, G.F.","year":"1960","unstructured":"Curran, P. F., and Schwartz, G. F. (1960). Na, Cl, and water transport by rat colon. J. gen. Physiol., 43, 555-571.","journal-title":"J. gen. Physiol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/00365521.1970.12096589","article-title":"The transmucosal electrical potential difference of rectum in the unanesthetized man","volume":"5","author":"Dalmark, M.","year":"1970","unstructured":"Dalmark, M. (1970). The transmucosal electrical potential difference of rectum in the unanesthetized man. Scand. J. Gastroent., 5, 277-282.","journal-title":"Scand. J. Gastroent"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1113\/jphysiol.1967.sp008379","article-title":"The gradient of electrical potential difference and of sodium and potassium of the gut contents along the caecum and colon of normal and sodium depleted rats","volume":"193","author":"Edmonds, C.J.","year":"1967","unstructured":"Edmonds, C. J. (1967). The gradient of electrical potential difference and of sodium and potassium of the gut contents along the caecum and colon of normal and sodium depleted rats. J. Physiol. (Lond.), 193, 571-588.","journal-title":"J. Physiol. (Lond.)"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1136\/gut.12.5.356","article-title":"Absorption of sodium and water by human rectum measured by a dialysis method","volume":"12","author":"Edmonds, C.J.","year":"1971","unstructured":"Edmonds, C. J. (1971). Absorption of sodium and water by human rectum measured by a dialysis method. Gut, 12, 356-362.","journal-title":"Gut"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1136\/gut.11.4.330","article-title":"Measurement of electrical potentials of the human rectum and pelvic colon in normal and aldosterone-treated patients","volume":"11","author":"Edmonds, C.J.; Godfrey, R.C.","year":"1970","unstructured":"Edmonds, C. J., and Godfrey, R. C. (1970). Measurement of electrical potentials of the human rectum and pelvic colon in normal and aldosterone-treated patients. Gut, 11, 330-337.","journal-title":"Gut"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0140-6736(70)91397-8","article-title":"Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism","volume":"2","author":"Edmonds, C.J.; Richards, P.","year":"1970","unstructured":"Edmonds, C. J., and Richards, P. (1970). Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism. Lancet, 2, 624-627.","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0005-2736(70)90267-1","article-title":"Effect of bile salts on transport across brush border of rabbit ileum","volume":"211","author":"Frizzell, R.A.; Schultz, S.G.","year":"1970","unstructured":"Frizzell, R. A., and Schultz, S. G. (1970). Effect of bile salts on transport across brush border of rabbit ileum. Biochim. biophys. Acta (Amst.), 211, 589-592.","journal-title":"Biochim. biophys. Acta (Amst.)"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1136\/gut.10.11.921","article-title":"Transmural electrical potential difference of the human colon","volume":"10","author":"Geall, M.G.; Spencer, R.J.; Phillips, S.F.","year":"1969","unstructured":"Geall, M. G., Spencer, R. J., and Phillips, S. F. (1969). Transmural electrical potential difference of the human colon. Gut, 10, 921-923.","journal-title":"Gut"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3109\/00365517009046246","article-title":"Plasma renin concentration measured by use of radioimmunoassay for angiotensin","volume":"26","year":"1970","unstructured":"Giese, J., Jorgensen, M., Nielsen, M. D., Lund, J. O., and Munck, 0. (1970). Plasma renin concentration measured by use of radioimmunoassay for angiotensin I. Scand. J. clin. Lab. Invest., 26, 355-367.","journal-title":"I. Scand. J. clin. Lab. Invest"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0016-5085(19)33712-6","article-title":"Active transport of sodium by human colon in vitro","volume":"59","author":"Grady, G.F.; Duhamel, R.C.; Moore, E.W.","year":"1970","unstructured":"Grady, G. F., Duhamel, R. C., and Moore, E. W. (1970). Active transport of sodium by human colon in vitro. Gastroenterology, 59, 583-588.","journal-title":"Gastroenterology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0016-5085(67)80140-9","article-title":"The syndrome of ileal disease and the broken enterohepatic circulation: cholerheic enteropathy","volume":"52","author":"Hofmann, A.F.","year":"1967","unstructured":"Hofmann, A. F. (1967). The syndrome of ileal disease and the broken enterohepatic circulation: cholerheic enteropathy. Gastroenterology, 52, 752-757.","journal-title":"Gastroenterology"},{"key":"ref_13","first-page":"739","article-title":"Effect of intravenous anti-diuretic hormone administration on salt and water absorption from the human colon","volume":"72","author":"Levitan, R.; Mauer, I.","year":"1968","unstructured":"Levitan, R., and Mauer, I. (1968). Effect of intravenous anti-diuretic hormone administration on salt and water absorption from the human colon. J. Lab. clin. Med., 72, 739-746.","journal-title":"J. Lab. clin. Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1210\/jcem-30-5-682","article-title":"A radioimmunoassay for plasma aldosterone","volume":"30","author":"Mayes, D.; Furuyama, S.; Kem, D.C.; Nugent, C.A.","year":"1970","unstructured":"Mayes, D., Furuyama, S., Kem, D. C., and Nugent, C. A. (1970). A radioimmunoassay for plasma aldosterone. J. clin. Endocr., 30, 682-685.","journal-title":"J. clin. Endocr"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1172\/JCI106644","article-title":"Colonic secretion of water and electrolytes induced by bile acids: Perfusion studies in man","volume":"50","author":"Mekhjian, H.S.; Phillips, S.F.; Hofmann, A.F.","year":"1971","unstructured":"Mekhjian, H. S., Phillips, S. F., and Hofmann, A. F. (1971). Colonic secretion of water and electrolytes induced by bile acids: Perfusion studies in man. J. clin. Invest., 50, 1569-1577.","journal-title":"J. clin. Invest"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1136\/bmj.2.5812.496","article-title":"Lithiuminduced hyperpolarization of the human rectum in vivo","volume":"1","author":"Rask-Madsen, J.; Baastrup, P.C.; Schwartz, M.","year":"1972","unstructured":"Rask-Madsen, J., Baastrup, P. C., and Schwartz, M. (1972). Lithiuminduced hyperpolarization of the human rectum in vivo. Brit. med. J., 1, 496-498.","journal-title":"Brit. med. J"},{"key":"ref_17","doi-asserted-by":"crossref","DOI":"10.1080\/00365521.1973.12096688","article-title":"Electrolyte transport capacity and electrical potentials across the normal and the inflamed human rectum in vivo","author":"Rask-Madsen, J.; Jensen, P.B.","year":"1973","unstructured":"Rask-Madsen, J., and Jensen, P. B. (1973). Electrolyte transport capacity and electrical potentials across the normal and the inflamed human rectum in vivo. Scand. J. Gastroent., in press.","journal-title":"Scand. J. Gastroent"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S0021-9258(18)72872-X","article-title":"A simple and accurate method for the determination of chloride in biological fluids","volume":"140","author":"Schales, O.; Schales, S.S.","year":"1941","unstructured":"Schales, O., and Schales, S. S. (1941). A simple and accurate method for the determination of chloride in biological fluids. J. biol. Chem., 140, 879-884.","journal-title":"J. biol. Chem"},{"key":"ref_19","first-page":"357","article-title":"In Some Rapid Approximate Statistical Procedures. Lederle Laboratories Division, American Cyanamid","volume":"28","author":"Wilcoxon, F.; Wilcox, P.A.","year":"1964","unstructured":"Wilcoxon, F., and Wilcox, P. A. (1964). In Some Rapid Approximate Statistical Procedures. Lederle Laboratories Division, American Cyanamid Co., Pearl River, New York, Wrong, O., Metcalfe-Gibson, A., Morrison, R. B. I., Ng, S. T., and Howard, A. V. (1965). In vivo dialysis of faeces as a method of stool analysis. I. Technique and results in normal subjects. Clin. Sci., 28, 357-375.","journal-title":"Clin. Sci; In vivo dialysis of faeces as a method of stool analysis. I. Technique and results in normal subjects"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.14.5.390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T08:29:48Z","timestamp":1765614588000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.14.5.390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,5]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1973,5,1]]},"published-print":{"date-parts":[[1973,5]]}},"alternative-id":["10.1136\/gut.14.5.390"],"URL":"https:\/\/doi.org\/10.1136\/gut.14.5.390","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1973,5]]}}}