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H6p","volume":"36","author":"Delbarre, F.","year":"1960","unstructured":"Delbarre, F. (1960). L'ost6oporose des h6mochromatoses. Sem. H6p. Paris, 36, 3279-3294.","journal-title":"Paris"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/art.1780070106","article-title":"Hemochromatosis and arthritis","volume":"7","author":"Schumacher, Jr, H.R.","year":"1964","unstructured":"Schumacher, H. R., Jr., (1964). Hemochromatosis and arthritis. Arthr. and Rheum., 7, 41-50.","journal-title":"Arthr. and Rheum"},{"key":"ref_115","article-title":"The treatment of hemochromatosis by","author":"Weintraub, L.R.; Conrad, M.E.; Crosby, W.H.","year":"1966","unstructured":"Weintraub, L. R., Conrad, M. E., and Crosby, W. H. (1966). 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Douze ans de recul dans le traitment de l'h6mochromatose par saign6es r6p6t6es. Med."},{"key":"ref_119","first-page":"54","article-title":"Reversal of 'cirrhosis' in idiopathic haemochromatosis following long-term intensive venesection therapy","volume":"19","author":"Powell, L.W.; Kerr, J.F.R.","year":"1970","unstructured":"Powell, L. W., and Kerr, J. F. R. (1970). Reversal of 'cirrhosis' in idiopathic haemochromatosis following long-term intensive venesection therapy. Aust. Ann. Med., 19, 54-57.","journal-title":"Aust. Ann. Med"},{"key":"ref_120","article-title":"Chelating agents in the diagnosis and treatment of iron overload in thalassemia","author":"Smith, R.S.","year":"1964","unstructured":"Smith, R. S. (1964). 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