{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:53:45Z","timestamp":1758124425147,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1974,8]]},"abstract":"<jats:p>Serum gastrin concentrations and gastric acid secretion were measured in nine antrectomized subjects during infusion of saline and calcium gluconate. The basal gastrin level was of the same magnitude as in normal individuals and unoperated duodenal ulcer patients. Calcium infusion only induced gastrin release in one patient and did not induce acid secretion in any of the patients.<\/jats:p>","DOI":"10.1136\/gut.15.8.622","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"622-625","source":"Crossref","is-referenced-by-count":10,"title":["The effect of calcium on gastric acid and gastrin secretion in antrectomized subjects"],"prefix":"10.1136","volume":"15","author":[{"given":"J.","family":"Christiansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. F.","family":"Rehfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Stadil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1974,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0016-5085(67)80128-8","article-title":"Effects of induced hypercalcemia on human gastric secretion","volume":"52","author":"Barreras, R.F.; Donaldson, Jr, R.M.","year":"1967","unstructured":"Barreras, R. F., and Donaldson, R. M., Jr. (1967). Effects of induced hypercalcemia on human gastric secretion. Gastroenterology, 52, 670-675.","journal-title":"Gastroenterology"},{"issue":"399 402","key":"ref_2","article-title":"Calcium stimulated gastric secretion in the Zollinger-Ellison syndrome","volume":"101","author":"Basso, N.; Passaro, Jr, E.","year":"1970","unstructured":"Basso, N., and Passaro, E., Jr. (1970). Calcium stimulated gastric secretion in the Zollinger-Ellison syndrome. Arch. Surg., 101, 399 402.","journal-title":"Arch. Surg"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/00365527209180768","article-title":"Parathyroid adenoma and gastric acid secretion","volume":"7","author":"Christiansen, J.; Aagaard, P.","year":"1972","unstructured":"Christiansen, J., and Aagaard, P. (1972). Parathyroid adenoma and gastric acid secretion. Scand. J. Gastroent., 7, 445-449.","journal-title":"Scand. J. Gastroent"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1136\/gut.13.8.643","article-title":"Interaction of calcium and pentagastrin on gastric acid secretion in man","volume":"13","author":"Christiansen, J.; Hendel, L.","year":"1972","unstructured":"Christiansen, J., and Hendel, L. (1972). Interaction of calcium and pentagastrin on gastric acid secretion in man. Gut, 13, 643-645.","journal-title":"Gut"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1097\/00000658-197209000-00012","article-title":"Hyperparathyroidism: gastric acid secretion and gastrin","volume":"176","author":"Dent, R.I.; James, J.H.; Wang, C.; Deftos, L.J.; Talamo, R.; Fischer, J.E.","year":"1972","unstructured":"Dent, R. I., James, J. H., Wang, C., Deftos, L. J., Talamo, R., and Fischer, J. E. (1972). Hyperparathyroidism: gastric acid secretion and gastrin. Ann. Surg., 176, 360-369.","journal-title":"Ann. Surg"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1152\/jappl.1966.21.5.1607","article-title":"Hypercalcemia and gastric secretion in man","volume":"21","author":"Murphy, D.L.; Goldstein, H.; Boyle, J.D.; Ward, S.","year":"1966","unstructured":"Murphy, D. L., Goldstein, H., Boyle, J. D., and Ward, S. (1966). Hypercalcemia and gastric secretion in man. J. appl. Physiol., 21, 1607-1610.","journal-title":"J. appl. Physiol"},{"key":"ref_7","first-page":"95","volume-title":"Distribution of gastrin in the gastrointestinal tract of human, dog, cat, and hog. In Frontiers in Gastro-intestinal Hormone Research: Nobel Symposium","author":"Nilsson, G.; Yalow, R.S.; Berson, S.A.","year":"1973","unstructured":"Nilsson, G., Yalow, R. S., and Berson, S. A. (1973). Distribution of gastrin in the gastrointestinal tract of human, dog, cat, and hog. In Frontiers in Gastro-intestinal Hormone Research: Nobel Symposium XVI. Edited by S. Andersson, pp. 95-102. Almqvist and Wiksell, Stockholm."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/00000658-197010000-00002","article-title":"Influence of hypercalcemia on gastric secretion and serum gastrin concentrations in man","volume":"172","author":"Reeder, D.D.; Jackson, B.M.; Ban, J.; Clendinnen, B.G.; Davidson, W.D.; Thompson, J.C.","year":"1970","unstructured":"Reeder, D. D., Jackson, B. M., Ban, J., Clendinnen, B. G., Davidson, W. D., and Thompson, J. C. (1970). Influence of hypercalcemia on gastric secretion and serum gastrin concentrations in man. Ann. Surg., 172, 540-546.","journal-title":"Ann. Surg"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3109\/00365517209081114","article-title":"Production and evaluation of antibodies for the radioimmunoassay of gastrin","volume":"30","author":"Rehfeld, J.F.; Stadil, F.; Rubin, B.","year":"1972","unstructured":"Rehfeld, J. F., Stadil, F., and Rubin, B. (1972). Production and evaluation of antibodies for the radioimmunoassay of gastrin. Scand. J. clin. Lab Invest., 30, 221-232.","journal-title":"Scand. J. clin. Lab Invest"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/00365521.1973.12096753","article-title":"Gastrins in serum","volume":"8","author":"Rehfeld, J.F.","year":"1973","unstructured":"Rehfeld, J. F. (1973). Gastrins in serum. Scand. J. Gastroent., 8, 577-583.","journal-title":"Scand. J. Gastroent"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gut.15.2.102","article-title":"Immunoreactive gastrin components in human serum","volume":"15","author":"Rehfeld, J.F.; Stadil, F.; Vikels0e, J.","year":"1974","unstructured":"Rehfeld, J. F., Stadil, F., and Vikels0e, J. (1974). Immunoreactive gastrin components in human serum. Gut, 15, 102-111.","journal-title":"Gut"},{"issue":"207-21","key":"ref_12","first-page":"1","article-title":"The dissociation of gastric acid output and plasma gastrin concentration after calcium infusions in conscious monkeys","volume":"73","author":"Rosato, E.F.; Mullen, J.L.; Lanciault, G.; Rosato, F.E.; Brooks, F.P.","year":"1973","unstructured":"Rosato, E. F., Mullen, J. L., Lanciault, G., Rosato, F. E., and Brooks, F. P. (1973). The dissociation of gastric acid output and plasma gastrin concentration after calcium infusions in conscious monkeys. Surgery, 73, 207-21 1.","journal-title":"Surgery"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1136\/gut.8.6.592","article-title":"Effect of intravenous calcium administration on gastric secretion of acid and pepsin in man","volume":"8","author":"Smallwood, R.A.","year":"1967","unstructured":"Smallwood, R. A. (1967). Effect of intravenous calcium administration on gastric secretion of acid and pepsin in man. Gut, 8, 592-598.","journal-title":"Gut"},{"key":"ref_14","first-page":"61","article-title":"Radioimmunoassay of gastrin in human serum","volume":"9","author":"Stadil, F.; Rehfeld, J.F.","year":"1971","unstructured":"Stadil, F., and Rehfeld, J. F. (1971). Radioimmunoassay of gastrin in human serum. Scand. J. Gastroent., Suppl., 9, 61-65.","journal-title":"Scand. J. Gastroent"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3109\/00365517209080271","article-title":"Preparation of \"2'I-labelled synthetic human gastrin I for radioimmuno-analysis","volume":"30","author":"Stadil, F.; Rehfeld, J.F.","year":"1972","unstructured":"Stadil, F., and Rehfeld, J. F. (1972). Preparation of \"2'I-labelled synthetic human gastrin I for radioimmuno-analysis. Scand. J. clin. Lab. Invest., 30, 361-368.","journal-title":"Scand. J. clin. Lab. Invest"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/00365521.1973.12096677","article-title":"Determination of gastrin in serum: an evaluation of the reliability of a radioimmunoassay","volume":"8","author":"Stadil, F.; Rehfeld, J.F.","year":"1973","unstructured":"Stadil, F., and Rehfeld, J. F. (1973). Determination of gastrin in serum: an evaluation of the reliability of a radioimmunoassay. Scand. J. Gastroent., 8, 101-112.","journal-title":"Scand. J. Gastroent"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0016-5085(73)80157-X","article-title":"Gastrin release in postoperative ulcer patients: evidence for release of duodenal gastrin","volume":"64","author":"Stern, D.H.; Walsh, J.H.","year":"1973","unstructured":"Stern, D. H., and Walsh, J. H. (1973). Gastrin release in postoperative ulcer patients: evidence for release of duodenal gastrin. Gastroenterology, 64, 363-369.","journal-title":"Gastroenterology"},{"key":"ref_18","first-page":"26","article-title":"The biological role of cyclic-AMP. (Some areas of contrast with cyclic-GMP)","volume-title":"Progress in Endocrinology (International Congress Ser; Excerpta Medica Foundation, Amsterdam.","volume":"184","author":"Sutherland, E.W.; Hardman, J.G.; Butcher, R.W.; Broadus, A.E.","year":"1969","unstructured":"Sutherland, E. W., Hardman, J. G., Butcher, R. W. and Broadus, A. E. (1969). The biological role of cyclic-AMP. (Some areas of contrast with cyclic-GMP). In Progress in Endocrinology (International Congress Ser., No. 184), edited by C. Gual, pp. 26-32. Excerpta Medica Foundation, Amsterdam."},{"key":"ref_19","first-page":"145","article-title":"The role of cyclic-31,5'-AMP in response to catecholamines and other hormones","volume":"18","author":"Sutherland, E.W.; Robison, G.A.","year":"1966","unstructured":"Sutherland, E. W., and Robison, G. A. (1966). The role of cyclic-31,5'-AMP in response to catecholamines and other hormones. Pharmacol. Rev., 18, 145-161.","journal-title":"Pharmacol. Rev"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1056\/NEJM196910162811602","article-title":"Effects of calcium on serum gastrin levels in the Zollinger-Ellison syndrome","volume":"281","author":"Trudeau, W.L.; McGuigan, J.E.","year":"1969","unstructured":"Trudeau, W. L., and McGuigan, J. E. (1969). Effects of calcium on serum gastrin levels in the Zollinger-Ellison syndrome. New Engl. J. Med., 281, 862-866.","journal-title":"New Engl. J. Med"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.15.8.622","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T19:07:14Z","timestamp":1757272034000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.15.8.622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,8]]},"references-count":20,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1974,8,1]]},"published-print":{"date-parts":[[1974,8]]}},"alternative-id":["10.1136\/gut.15.8.622"],"URL":"https:\/\/doi.org\/10.1136\/gut.15.8.622","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1974,8]]}}}