{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T09:36:56Z","timestamp":1765618616533,"version":"3.48.0"},"reference-count":20,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1975,3]]},"abstract":"<jats:p>Fasting serum pyridoxal was assayed by an automated microbiological system in 50 patients with endoscopically confirmed active peptic ulceration. Thirty patients had gastric ulceration, 14 had duodenal, four had pyloric canal ulceration, and two had both a gastric and a duodenal ulcer. Serum pyridoxal was below normal in 28 of the gastric ulcer group and in one of the duodenal ulcer group. No difference in the age, sex, drug, alcohol intake, or diet could be distinguished between those two groups.<\/jats:p>","DOI":"10.1136\/gut.16.3.177","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"177-180","source":"Crossref","is-referenced-by-count":5,"title":["Serum pyridoxal in active peptic ulceration."],"prefix":"10.1136","volume":"16","author":[{"given":"C R","family":"Sanderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R E","family":"Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1975,3,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1136\/jcp.23.3.232","article-title":"The measurement of serum pyridoxal by a microbiological assay using Lactobacillus casei","volume":"23","author":"Anderson, B.B.; Peart, M.B.; Fulford-Jones, C.E.","year":"1970","unstructured":"Anderson, B. B., Peart, M. B., and Fulford-Jones, C. E. (1970). The measurement of serum pyridoxal by a microbiological assay using Lactobacillus casei. J. clin. Path., 23, 232-242.","journal-title":"J. clin. Path"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"389","DOI":"10.3181\/00379727-85-20891","article-title":"Effect of isoniazid in vitamin B, metabolism: its possible significance in producing isoniazid neuritis","volume":"85","author":"Biehl, J.P.; Vilter, R.W.","year":"1954","unstructured":"Biehl, J. P., and Vilter, R. W. (1954). Effect of isoniazid in vitamin B, metabolism: its possible significance in producing isoniazid neuritis. Proc. Soc. exp. Biol. (N. Y.), 85, 389-392.","journal-title":"Proc. Soc. exp. Biol. (N. Y.)"},{"key":"ref_3","first-page":"166","article-title":"Tryptophan metabolism as affected by anovulatory agents","author":"Brown, R.R.; Rose, D.P.; Price, J.M.; Wolf, H.","year":"1969","unstructured":"Brown, R. R., Rose, D. P., Price, J. M., and Wolf, H. (1969). Tryptophan metabolism as affected by anovulatory agents. Ann. N. Y. Acad. Sci., 166,44-56.","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1172\/JCI104292","article-title":"The effect of vitamin supplementation on the urinary excretion oftryptophan metabolites by pregnant women","volume":"40","author":"Brown, R.R.; Thornton, M.J.; Price, J.M.","year":"1961","unstructured":"Brown, R. R., Thornton, M. J., and Price, J. M. (1961). The effect of vitamin supplementation on the urinary excretion oftryptophan metabolites by pregnant women. J. clin. Invest., 40, 617-623.","journal-title":"J. clin. Invest"},{"key":"ref_5","first-page":"34","article-title":"A simple enzymic assay for pyridoxal phosphate","author":"Chabner, B.; Livingston, D.","year":"1970","unstructured":"Chabner, B., and Livingston, D. (1970). A simple enzymic assay for pyridoxal phosphate. Ann. Biochem., 34,413-423.","journal-title":"Ann. Biochem"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1136\/jcp.23.1.47","article-title":"An automated method for the measurement of folate activity","volume":"23","author":"Davis, R.E.; Nicol, D.J.; Kelly, A.","year":"1970","unstructured":"Davis, R. E., Nicol, D. J., and Kelly, A. (1970). An automated method for the measurement of folate activity. J. clin. Path., 23, 47-53.","journal-title":"J. clin. Path"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5694\/j.1326-5377.1974.tb70837.x","article-title":"Pyridoxal and folate deficiency in alcoholics","volume":"2","author":"Davis, R.E.; Smith, B.K.","year":"1974","unstructured":"Davis, R. E., and Smith, B. K. (1974a). Pyridoxal and folate deficiency in alcoholics. Med. J. Aust., 2, 357-360.","journal-title":"Med. J. Aust"},{"issue":"1937-1940","key":"ref_8","article-title":"Pyridoxal, vitamin B,, and folate metabolism in women taking oral contraceptive agents","volume":"48","author":"Davis, R.E.; Smith, B.K.","year":"1974","unstructured":"Davis, R. E., and Smith, B. K. (1974b). Pyridoxal, vitamin B,, and folate metabolism in women taking oral contraceptive agents. S. Afr. med. J., 48,1937-1940.","journal-title":"S. Afr. med. J"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/jcp.26.11.871","article-title":"An automated method for the microbiological assay of serum pyridoxal","volume":"26","author":"Davis, R.E.; Smith, B.K.; Curnow, D.H.","year":"1973","unstructured":"Davis, R. E., Smith, B. K., and Curnow, D. H. (1973). An automated method for the microbiological assay of serum pyridoxal. J. clin. Path., 26, 871-874.","journal-title":"J. clin. Path"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0140-6736(71)92480-9","article-title":"L-dopa as a vitamin B, antagonist","volume":"1","author":"Evered, D.F.","year":"1971","unstructured":"Evered, D. F. (1971). L-dopa as a vitamin B, antagonist. (Letter.) Lancet, 1, 914.","journal-title":"(Letter.) Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0021-9258(18)51202-3","article-title":"A phosphorylated derivative of pyridoxal as the coenzyme of tyrosine decarboxylase","volume":"155","author":"Gunsalus, I.C.; Bellamy, W.D.; Umbreit, W.W.","year":"1944","unstructured":"Gunsalus, I. C., Bellamy, W. D., and Umbreit, W. W. (1944). A phosphorylated derivative of pyridoxal as the coenzyme of tyrosine decarboxylase. J. biol. Chem., 155, 685-686.","journal-title":"J. biol. Chem"},{"article-title":"Tryptophan level tests and pyridoxal-5-phosphate levels in epileptic children","year":"1966","key":"ref_12","unstructured":"Hagberg, B., Hamfelt, A., and Hansson, 0. (1966). Tryptophan level tests and pyridoxal-5-phosphate levels in epileptic children."},{"key":"ref_13","article-title":"Antipyridoxine effect of D-penicillamine in schizophrenic men","author":"Hollister, L.E.; Moore, F.F.; Forrest, F.; Bennett, J.L.","year":"1966","unstructured":"Hollister, L. E., Moore, F. F., Forrest, F., and Bennett, J. L. (1966). Antipyridoxine effect of D-penicillamine in schizophrenic men."},{"key":"ref_14","first-page":"103","article-title":"Pyridoxine-responsive anemia: analysis of 62 cases","volume":"12","author":"Horrigan, D.L.; Harris, J.W.","year":"1964","unstructured":"Horrigan, D. L., and Harris, J. W. (1964). Pyridoxine-responsive anemia: analysis of 62 cases. Advanc. intern. Med., 12, 103-174.","journal-title":"Advanc. intern. Med"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0021-9258(18)72229-1","article-title":"Xanthurenic acid and its role in the tryptophane metabolism of pyridoxinedeficient rats","volume":"149","author":"Lepkovsky, S.; Roboc, E.; Haagen-Smit, A.J.","year":"1943","unstructured":"Lepkovsky, S., Roboc, E., Haagen-Smit, A. J. (1943). Xanthurenic acid and its role in the tryptophane metabolism of pyridoxinedeficient rats. J. biol. Chem., 149, 195-201.","journal-title":"J. biol. Chem"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"841","DOI":"10.3181\/00379727-98-24203","article-title":"Association of pyridoxine deficiency and convulsions in alcoholics","volume":"98","author":"Lerner, A.M.; De Carli, L.M.; Davidson, C.S.","year":"1958","unstructured":"Lerner, A. M., De Carli, L. M., and Davidson, C. S. (1958). Association of pyridoxine deficiency and convulsions in alcoholics. Proc. Soc. exp. Biol. (N. Y.), 98, 841-843.","journal-title":"Proc. Soc. exp. Biol. (N. Y.)"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1172\/JCI107607","article-title":"Vitamin B, metabolism in chronic alcohol abuse","volume":"53","author":"Lumeng, L.; Li, T.K.","year":"1974","unstructured":"Lumeng, L., and Li, T. K. (1974). Vitamin B, metabolism in chronic alcohol abuse. J. clin. Invest., 53, 693-704.","journal-title":"J. clin. Invest"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2141.1965.tb00085.x","article-title":"Sideroblastic anaemia in man: observations on seventy cases","volume":"11","author":"MacGibbon, B.H.; Mollin, D.L.","year":"1965","unstructured":"MacGibbon, B. H., and Mollin, D. L. (1965). Sideroblastic anaemia in man: observations on seventy cases. Brit. J. Haemat., 11, 59-69. National Research Council (1968). Recommended Dietary Allowances: A Report of the Food and Nutrition Board. National Academy ofSciences, Washington, D.C. Nicholas, D. R., and Pitney, W. R. (1958). Microbiological assay of vitamin B1, content of serum using Euglena gracilis. Aust. J.","journal-title":"Brit. J. Haemat; Recommended Dietary Allowances: A Report of the Food and Nutrition Board"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/B978-1-4831-6750-3.50009-3","article-title":"Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites","volume":"2","author":"Price, J.M.; Brown, R.R.; Yess, N.","year":"1965","unstructured":"Price, J. M., Brown, R. R., and Yess, N. (1965). Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites. Advanc. metab. Dis., 2, 159-225.","journal-title":"Advanc. metab. Dis"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"\"pp. 44","DOI":"10.1016\/B978-1-4831-9703-6.50016-9","volume":"2","author":"Sauberlich, H.E.","year":"1968","unstructured":"Sauberlich, H. E. (1968). In The Vitamins, edited by W. H. Sebrell and R. S. Harris, vol. 2, pp. 44-80. Academic Press, New York. Vilter, R. W. (1956). The metabolism of vitamin B, in human beings. Amer. J. clin. Nutr., 4, 378-385.","journal-title":"The Vitamins; Nutr"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.16.3.177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T09:33:51Z","timestamp":1765618431000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.16.3.177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,3]]},"references-count":20,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1975,3,1]]},"published-print":{"date-parts":[[1975,3]]}},"alternative-id":["10.1136\/gut.16.3.177"],"URL":"https:\/\/doi.org\/10.1136\/gut.16.3.177","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1975,3]]}}}