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Analysis of the results of the propranolol study suggests that an increase in the rate of absorption combined with saturation of first pass extraction may account for the increased plasma concentrations of unchanged propranolol found in coeliac disease. These abnormalities of drug absorption do not appear to be related to the duration of treatment with a gluten free diet.<\/jats:p>","DOI":"10.1136\/gut.17.2.139","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"139-143","source":"Crossref","is-referenced-by-count":27,"title":["Absorption of propranolol and practolol in Coeliac disease."],"prefix":"10.1136","volume":"17","author":[{"given":"R L","family":"Parsons","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C M","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Raymond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J R","family":"Trounce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1976,2,1]]},"reference":[{"key":"ref_1","first-page":"6","article-title":"Intraluminal pH of duodenum and jejunum in fasting subjects with normal and abnormal gastric or pancreatic function","author":"Benn, A.; Cooke, W.T.","year":"1971","unstructured":"Benn, A., and Cooke, W. 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Athens 1973, 1, 499-551. Edited by G. K. Daikos. Hellenic Society for Chemotherapy: Athens."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/jac\/1.1.39","article-title":"The absorption of antibiotics in adult patients with coeliac disease","volume":"1","author":"Parsons, R.L.; Hossack, G.; Paddock, G.","year":"1975","unstructured":"Parsons, R. L., Hossack, G., and Paddock, G. (1975). The absorption of antibiotics in adult patients with coeliac disease. Journal ofAntimicrobial Chemotherapy, 1, 39-50.","journal-title":"Journal ofAntimicrobial Chemotherapy"},{"key":"ref_12","first-page":"348","article-title":"Plasma propranolol and practolol in adult coeliac disease","volume":"1","author":"Parsons, R.L.; Kaye, C.M.","year":"1974","unstructured":"Parsons, R. L., and Kaye, C. M. (1974). Plasma propranolol and practolol in adult coeliac disease. 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