{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:12:30Z","timestamp":1791943950896,"version":"4.3.4"},"reference-count":30,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1977,7]]},"abstract":"<jats:p>The effect of fat malabsorption on the absorption and renal excretion of dietary oxalate was studied in four patients with sprue and in two patients with dermatitis herpetiformis and sprue-like jejunal histology. Hyperoxaluria was present in all patients with sprue when fat malabsorption was severe. Urinary oxalate excretion decreased in two of the three patients with coeliac sprue when their fat malabsorption had improved after three months of dietary gluten restriction. Neither patient with dermatitis herpetiformis and sprue had steatorrhoea. In these patients, urinary oxalate excretion was always within normal limits. A significant positive linear relationship (y=28.25 +4-84x; r=0-82; P less than 0-01) was demonstrated between faecal fat and urinary oxalate excretion. The results of this study support the concept that severe malabsorption of dietary fat plays a primary causative role in enteric hyperoxaluria.<\/jats:p>","DOI":"10.1136\/gut.18.7.561","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"561-566","source":"Crossref","is-referenced-by-count":33,"title":["Hyperoxaluria correlates with fat malabsorption in patients with sprue."],"prefix":"10.1136","volume":"18","author":[{"given":"G B","family":"McDonald","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D L","family":"Earnest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W H","family":"Admirand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1977,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1136\/gut.12.12.973","article-title":"The effect of fat on calcium absorption from a mixed meal in normal subjects, patients with malabsorptive disease, and patients with a partial gastrectomy","volume":"12","author":"Agnew, J.E.; Holdsworth, C.D.","year":"1971","unstructured":"Agnew, J. 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(1973). Urinary tract calculi after intestinal shunt operations for the treatment of obesity. Surgery, Gynecology and Obstetrics, 136, 257-260.","journal-title":"Surgery, Gynecology and Obstetrics"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/S0016-5085(76)80318-6","article-title":"Effect of bile salts and fatty acids on the colonic absorption of oxalate","volume":"70","author":"Dobbins, J.W.; Binder, H.J.","year":"1976","unstructured":"Dobbins, J. W., and Binder, H. J. (1976). Effect of bile salts and fatty acids on the colonic absorption of oxalate. Gastroenterology, 70, 1096-1100.","journal-title":"Gastroenterology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S0140-6736(71)91840-X","article-title":"Hyperoxaluria and renal calculi in ileal disease","volume":"1","author":"Dowling, R.H.; Rose, G.A.; Sutor, D.J.","year":"1971","unstructured":"Dowling, R. H., Rose, G. A., and Sutor, D. J. (1971). 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(1974)."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1080\/00365521.1974.12096914","article-title":"Assessment of jejunal function in patients with dermatitis herpetiformis and adult coeliac disease using a perfusion technique","volume":"9","unstructured":"Assessment of jejunal function in patients with dermatitis herpetiformis and adult coeliac disease using a perfusion technique. Scandinavian Journal of Gastroenterology, 9, 793-798.","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0002-9610(74)90150-0","article-title":"Urinary tract stone after small bowel bypass for morbid obesity","volume":"127","author":"O'Leary, J.P.; Thomas, Jr., W.C.; Woodward, E.R.","year":"1974","unstructured":"O'Leary, J. P., Thomas, W. C., Jr., and Woodward, E. R. (1974). Urinary tract stone after small bowel bypass for morbid obesity. 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Role of dietary oxalate","volume":"79","author":"Stauffer, J.Q.; Humphreys, M.H.; Weir, G.J.","year":"1973","unstructured":"Stauffer, J. Q., Humphreys, M. H., and Weir, G. J. (1973). Acquired hyperoxaluria with regional enteritis after ileal resection. Role of dietary oxalate. Annals of Internal Medicine, 79, 383-391.","journal-title":"Annals of Internal Medicine"},{"key":"ref_29","first-page":"783","article-title":"Acquired hyperoxaluria: relationship to dietary calcium content and severity of steatorrhea","volume":"66","author":"Stauffer, J.Q.; Stewart, R.J.; Bertrand, G.","year":"1974","unstructured":"Stauffer, J. Q., Stewart, R. J., and Bertrand, G. (1974). Acquired hyperoxaluria: relationship to dietary calcium content and severity of steatorrhea. Gastroenterology, 66, 783. (Abstract).","journal-title":"Gastroenterology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1079\/BJN19620061","article-title":"The oxalic acid content of English diets","volume":"16","author":"Zarembski, P.M.; Hodgkinson, A.","year":"1962","unstructured":"Zarembski, P. M., and Hodgkinson, A. (1962). The oxalic acid content of English diets. 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