{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T04:39:12Z","timestamp":1765082352707,"version":"3.46.0"},"reference-count":15,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1977,8]]},"abstract":"<jats:p>IgA class reticulin antibodies were not found in patients with Crohn's disease, ulcerative colitis, and hiatus hernia despite a significant incidence of IgG class reticulin antibodies. None of 56 normal healthy subjects was positive. In contrast, 13 (76%) of the sera from 17 patients with coeliac disease on normal diet were positive for IgA class antibodies as were 19 (20%) of 93 first degree relatives. Seventy-three relatives underwent jejunal biopsy. Grade III (flat) histology was found in 13 and, of these patients, 10 (77%) showed IgA class reticulin antibody in their serum. It is suggested that determination of IgA class reticulin antibodies was a useful test to determine which relative must be biopsied.<\/jats:p>","DOI":"10.1136\/gut.18.8.647","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"647-650","source":"Crossref","is-referenced-by-count":18,"title":["IgA class reticulin antibodies in relatives of patients with coeliac disease."],"prefix":"10.1136","volume":"18","author":[{"given":"E G","family":"Mallas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Williamson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B T","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W T","family":"Cooke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1977,8,1]]},"reference":[{"key":"ref_1","first-page":"682","article-title":"Autoantibodies to reticulin in patients with idiopathic steatorrhoea, coeliac disease, and Crohn's disease, and their relation to immunoglobulins and dietary antibodies","volume":"2","author":"Alp, M.H.; Wright, R.","year":"1971","unstructured":"Alp, M. H., and Wright, R. (1971). Autoantibodies to reticulin in patients with idiopathic steatorrhoea, coeliac disease, and Crohn's disease, and their relation to immunoglobulins and dietary antibodies. Lancet, 2, 682-685.","journal-title":"Lancet"},{"key":"ref_2","first-page":"373","article-title":"Autoantibodies in children with coeliac disease","volume":"13","author":"Brown, I.L.; Ferguson, A.; Carswell, F.; Home, C.H.W.; MacSween, R.N.M.","year":"1973","unstructured":"Brown, I. L., Ferguson, A., Carswell, F., Home, C. H. W., and MacSween, R. N. M. (1973). Autoantibodies in children with coeliac disease. 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N., Peters, T. J., and Doe, W. F. (1974). Studies on the nature and significance of connective tissue antibodies in adult coeliac disease and Crohn's disease. Gut, 15, 284-288.","journal-title":"Gut"},{"key":"ref_5","first-page":"527","article-title":"Familial coeliac disease","volume":"41","author":"Mylotte, M.; Egan-Mitchell, B.; Fottrell, P.F.; McNicholl, B.; McCarthy, C.F.","year":"1972","unstructured":"Mylotte, M., Egan-Mitchell, B., Fottrell, P. F., McNicholl, B., and McCarthy, C. F. (1972). Familial coeliac disease. (Abstract). Quarterly Journal of Medicine, 41, 527-528.","journal-title":"(Abstract). Quarterly Journal of Medicine"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1136\/jcp.26.11.841","article-title":"Types of 'reticulin' antibodies detected in human sera by immunofluorescence","volume":"26","author":"Rizzetto, M.; Doniach, D.","year":"1973","unstructured":"Rizzetto, M., and Doniach, D. (1973). 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