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The EM Positive group showed a significantly greater percentage response to caloric restriction (P less than 0.01) and an exaggerated response to nicotinic acid stimulation when compared with the EM Negative group and normal controls. These results suggest that SER hypertrophy is not, as previously suggested, a constant feature of Gilbert's syndrome but rather a characteristic of a distinct subpopulation.<\/jats:p>","DOI":"10.1136\/gut.20.10.848","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"848-853","source":"Crossref","is-referenced-by-count":18,"title":["Gilbert's syndrome: evidence of morphological heterogeneity."],"prefix":"10.1136","volume":"20","author":[{"given":"J","family":"Dawson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D L","family":"Carr-Locke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I C","family":"Talbot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F D","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1979,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1172\/JCI104682","article-title":"Chronic unconjugated hyperbilirubinemia without overt signs of hemolysis in adolescents and adults","volume":"41","author":"Arias, I.M.","year":"1962","unstructured":"Arias, I. 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