{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:40:33Z","timestamp":1790206833300,"version":"4.1.0"},"reference-count":55,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p>Achalasia is an esophageal motility disorder of unknown cause, characterised by aperistalsis of the esophageal body and impaired lower esophageal sphincter relaxation. Patients present at all ages, primarily with dysphagia for solids\/liquids and bland regurgitation. The diagnosis is suggested by barium esophagram or endoscopy and confirmed by esophageal manometry. Achalasia cannot be cured. Instead, our goal is to relieve symptoms, improve esophageal emptying and prevent the development of megaesophagus. The most successful therapies are pneumatic dilation and surgical myotomy. The advantages of pneumatic dilation include an outpatient procedure, minimal pain, return to work the next day, mild if any GERD, and can be performed in any age group and even during pregnancy. Pneumatic dilation does not hinder future myotomy, and all cost analyses find it less expensive than Heller myotomy. Laparoscopic myotomy with a partial fundoplication has the advantage of being a single procedure, dysphagia relief is longer at the cost of more troubling heartburn, and a myotomy may be more effective treatment in adolescents and younger adults, especially men. Over a two year horizon, the clinical success of pneumatic dilation and laparoscopic myotomy are comparable in a recent large European randomised trial. The prognosis for achalasia patients to return to near-normal swallowing and good quality of life are excellent, but few are \u201ccured\u201d with a single treatment and intermittent \u201ctouch up\u201d procedures may be required.<\/jats:p>","DOI":"10.1136\/gut.2010.212423","type":"journal-article","created":{"date-parts":[[2011,2,8]],"date-time":"2011-02-08T21:12:31Z","timestamp":1297199551000},"page":"869-876","source":"Crossref","is-referenced-by-count":120,"title":["Management of achalasia: surgery or pneumatic dilation"],"prefix":"10.1136","volume":"60","author":[{"given":"Joel E","family":"Richter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy E","family":"Boeckxstaens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2011,2,8]]},"reference":[{"key":"2025121300250108000_60.6.869.1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013242831900"},{"key":"2025121300250108000_60.6.869.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01956.x"},{"key":"2025121300250108000_60.6.869.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01967.x"},{"key":"2025121300250108000_60.6.869.4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.33.8.1011"},{"key":"2025121300250108000_60.6.869.5","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.07.022"},{"key":"2025121300250108000_60.6.869.6","doi-asserted-by":"publisher","DOI":"10.1080\/00365520510012118"},{"key":"2025121300250108000_60.6.869.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70493-2"},{"key":"2025121300250108000_60.6.869.8","doi-asserted-by":"crossref","first-page":"S1635","DOI":"10.1016\/S0016-5085(03)81186-1","article-title":"Management of achalasia at a tertiary center-a complicated disease","volume":"124","author":"Vela","year":"2003","journal-title":"Gastroenterology"},{"key":"2025121300250108000_60.6.869.9","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1016\/0016-5085(92)91428-7","article-title":"Predictors of outcome in patients with achalasia treated by pneumatic dilation","volume":"103","author":"Eckardt","year":"1992","journal-title":"Gastroenterology"},{"key":"2025121300250108000_60.6.869.10","first-page":"34","article-title":"Graded pneumatic dilation using Rigiflex achalasia dilators in patients with primary esophageal achalasia","volume":"88","author":"Kadakia","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"2025121300250108000_60.6.869.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.09.020"},{"key":"2025121300250108000_60.6.869.12","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(05)00986-9"},{"key":"2025121300250108000_60.6.869.13","doi-asserted-by":"publisher","DOI":"10.1586\/17474124.2.3.435"},{"key":"2025121300250108000_60.6.869.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00385.x"},{"key":"2025121300250108000_60.6.869.15","doi-asserted-by":"publisher","DOI":"10.1136\/gut.12.4.268"},{"key":"2025121300250108000_60.6.869.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(97)70142-1"},{"key":"2025121300250108000_60.6.869.17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40099.x"},{"key":"2025121300250108000_60.6.869.18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.6.765"},{"key":"2025121300250108000_60.6.869.19","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015811001267"},{"key":"2025121300250108000_60.6.869.20","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-007-9364-z"},{"key":"2025121300250108000_60.6.869.21","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200411000-00004"},{"key":"2025121300250108000_60.6.869.22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01062.x"},{"key":"2025121300250108000_60.6.869.23","unstructured":"Boeckxstaens GE Annese V Bruley des Varannes S . 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