{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:23:01Z","timestamp":1771629781789,"version":"3.50.1"},"reference-count":9,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1980,10]]},"abstract":"<jats:p>Conflicting claims have been made regarding the physiological characteristics of the pyloric sphincter. Pyloric sphincter pressures were studied in 32 patients under basal conditions, after stimulation with HCl and posture changes. At gastroscopy a 2 mm diameter manometer catheter was placed in the duodenum and three to five hours later the catheter was withdrawn slowly with continuous manometry. Lower esophageal sphincter pressures fell within the expected range but there was no definite evidence of a pressure barrier at the pylorus in any group of patients. The technique caused no patient discomfort and minimal distortion of the region under study, indicating that the pylorus is usually patent with a lumenal diameter greater than 2 mm.<\/jats:p>","DOI":"10.1136\/gut.21.10.826","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"826-828","source":"Crossref","is-referenced-by-count":14,"title":["Atraumatic non-distorting pyloric sphincter pressure studies."],"prefix":"10.1136","volume":"21","author":[{"given":"A J","family":"McShane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"O'Morain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J R","family":"Lennon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J B","family":"Coakley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B G","family":"Alton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,10,1]]},"reference":[{"key":"ref_1","first-page":"67","article-title":"Physiological characteristics of the","volume-title":"human pyloric sphincter. Gastroenterology 1973; 64","author":"Fisher, R.; Cohen, S.","unstructured":"Fisher R, Cohen S. Physiological characteristics of the human pyloric sphincter. Gastroenterology 1973; 64: 67-75."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0016-5085(76)80481-7","article-title":"Manometric studies on the human pyloric sphincter: effect of cigarette smoking, metoclopramide and atropine","volume":"70","author":"Valenzuela, J.E.; Defilippi, C.; Csendes, A.","year":"1976","unstructured":"Valenzuela JE, Defilippi C, Csendes A. Manometric studies on the human pyloric sphincter: effect of cigarette smoking, metoclopramide and atropine. Gastroenterology 1976; 70: 481-3.","journal-title":"Gastroenterology"},{"issue":"80","key":"ref_3","first-page":"\"4Fyke\" # \"145","article-title":"Manometric studies","volume":"477","author":"Kaye, M.D.; Mehta, S.J.; Showalter, J.P.","year":"1956","unstructured":"Kaye MD, Mehta SJ, Showalter JP. Manometric studies of the human pylorus. Gastroenterology 1976; 70:477-80. 4Fyke FR,Code CF, Schlegel JF. The gastroesophageal sphincter in healthy human beings. Gastroenterologia (Basel) 1956; 86: 145-50.","journal-title":"of the human pylorus. Gastroenterology 1976; 70; Gastroenterologia (Basel); The gastroesophageal sphincter in healthy human beings"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0016-5085(19)33600-5","article-title":"Manometric configuration of the lower esophageal sphincter in normal human subjects","volume":"61","author":"Kaye, M.D.; Showalter, J.P.","year":"1971","unstructured":"Kaye MD, Showalter JP. Manometric configuration of the lower esophageal sphincter in normal human subjects. Gastroenterology 1971; 61: 213-23.","journal-title":"Gastroenterology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/gut.6.2.163","article-title":"The pressure profile of the gastroduodenal junctional zone in dogs","volume":"6","author":"Brink, B.M.; Schlegel, J.F.; Code, C.F.","year":"1965","unstructured":"Brink BM, Schlegel JF, Code CF. The pressure profile of the gastroduodenal junctional zone in dogs. Gut 1965;6: 163-71.","journal-title":"Gut"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1172\/JCI107297","article-title":"The hormonal regulation of pyloric sphincter function","volume":"52","author":"Fisher, R.S.; Lipshutz, W.; Cohen, S.","year":"1973","unstructured":"Fisher RS, Lipshutz W, Cohen S. The hormonal regulation of pyloric sphincter function. J Clin Invest 1973;52: 1289-96.","journal-title":"J Clin Invest"},{"key":"ref_7","first-page":"918","article-title":"Comparison of cardiac and pyloric sphincters, a manometric study","volume":"2","author":"Atkinson, M.; Edwards, D.A.W.; Honour, A.J.; Rowlands, E.N.","year":"1957","unstructured":"Atkinson M, Edwards DAW, Honour AJ, Rowlands EN. Comparison of cardiac and pyloric sphincters, a manometric study. Lancet 1957; 2: 918-22.","journal-title":"Lancet"},{"key":"ref_8","first-page":"100","article-title":"Gastroscopic observation of the dynamic anatomy of the antrum and pylorus","volume":"14","author":"Rider, J.A.; Moeller, H.C.; Puletti, E.J.","year":"1967","unstructured":"Rider JA, Moeller HC, Puletti EJ. Gastroscopic observation of the dynamic anatomy of the antrum and pylorus. Gastrointest Endosc 1967; 14: 100-1.","journal-title":"Gastrointest Endosc"},{"key":"ref_9","first-page":"163","volume-title":"Pylorus identification. Gastroenterology 1969; 57","author":"Blackwood, W.D.","unstructured":"Blackwood WD. Pylorus identification. Gastroenterology 1969; 57: 163-7."}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.21.10.826","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T03:16:14Z","timestamp":1765077374000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.21.10.826"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,10]]},"references-count":9,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1980,10,1]]},"published-print":{"date-parts":[[1980,10]]}},"alternative-id":["10.1136\/gut.21.10.826"],"URL":"https:\/\/doi.org\/10.1136\/gut.21.10.826","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,10]]}}}