{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T21:00:40Z","timestamp":1765659640089,"version":"3.48.0"},"reference-count":6,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1980,2]]},"abstract":"<jats:p>Though amoebic liver abscess and liver cirrhosis occur very commonly in hospital practice in the tropics, they have not to the knowledge of the present authors hitherto been reported to occur simultaneously in the same patient. The patient described here, who had clear-cut clinical and histological features of chronic liver cirrhosis with portal hypertension and ascites, presented somewhat acutely with liver pain and an amoebic liver abscess that contained 'chocolate sauce' on needle aspiration. The amoebic abscess, although, no doubt, superimposed on chronic irreversible cirrhosis, rapidly regressed on metronidazole therapy. The infrequency with which liver abscess and liver cirrhosis coexist cannot be satisfactorily explained. It is probable, however, that extensive scarring in the liver may prevent entamoeba histolytica from thriving.<\/jats:p>","DOI":"10.1136\/gut.21.2.161","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"161-163","source":"Crossref","is-referenced-by-count":9,"title":["Amoebic abscess in the cirrhotic liver."],"prefix":"10.1136","volume":"21","author":[{"given":"J M","family":"Falaiye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G C","family":"Okeke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A O","family":"Fregene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,2,1]]},"reference":[{"key":"ref_1","first-page":"1243","article-title":"Chronic liver disease and primary liver cell cancer with hepatitisassociated (Australia) antigen in serum","volume":"1","author":"Sherlock, S.; Fox, R.A.; Niazi, S.P.; Scheuer, P.J.","year":"1970","unstructured":"Sherlock S, Fox RA, Niazi SP, Scheuer PJ. Chronic liver disease and primary liver cell cancer with hepatitisassociated (Australia) antigen in serum. Lancet 1970; 1: 1243-7.","journal-title":"Lancet"},{"key":"ref_2","first-page":"389","article-title":"Hepatic amoebiasis: a study of 250 cases","volume":"27","author":"Lamont, N.M.; Pooler, N.R.","year":"1958","unstructured":"Lamont NM, Pooler NR. Hepatic amoebiasis: a study of 250 cases. Q J Med 1958; 27: 389-412.","journal-title":"Q J Med"},{"key":"ref_3","first-page":"111","article-title":"Amoebic liver abscess: A review of 113 Cases","volume":"19","author":"Lewis, E.A.; Antia, A.U.","year":"1970","unstructured":"Lewis EA, Antia AU. Amoebic liver abscess: A review of 113 Cases. West Afr Med J 1970; 19: 111-4.","journal-title":"West Afr Med J"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/jcp.22.4.427","article-title":"Evaluation in clinical practice of the fluorescent amoebic antibody test","volume":"22","author":"Jeanes, A.L.","year":"1969","unstructured":"Jeanes AL. Evaluation in clinical practice of the fluorescent amoebic antibody test. J Clin Pathol 1969; 22: 427-429.","journal-title":"J Clin Pathol"},{"key":"ref_5","first-page":"390424","article-title":"Chronic hepatitis. In Diseases of the Liver and Biliary System","author":"Sherlock, S.","year":"1975","unstructured":"Sherlock S. Chronic hepatitis. In Diseases of the Liver and Biliary System. Oxford: Blackwell 1975: 390424."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0035-9203(77)90038-4","article-title":"The epidemiology of infection with entamoeba histolytica in The Gambia, West Africa","volume":"71","author":"Bray, R.S.; Harris, W.S.","year":"1977","unstructured":"Bray RS, Harris WS. The epidemiology of infection with entamoeba histolytica in The Gambia, West Africa. Trans R Soc Trop Med Hyg 1977; 71: 401-7.","journal-title":"Trans R Soc Trop Med Hyg"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.21.2.161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T20:58:13Z","timestamp":1765659493000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.21.2.161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,2]]},"references-count":6,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1980,2,1]]},"published-print":{"date-parts":[[1980,2]]}},"alternative-id":["10.1136\/gut.21.2.161"],"URL":"https:\/\/doi.org\/10.1136\/gut.21.2.161","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1980,2]]}}}