{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T09:17:18Z","timestamp":1765617438453,"version":"3.48.0"},"reference-count":19,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1980,5]]},"abstract":"<jats:p>The therapeutic approach to the management of corrosive burns of the upper gastrointestinal tract leaves a considerable morbidity and a heavy mortality rate. This work evaluates the effectiveness of a new therapeutic approach given to 94 consecutive patients. The management has been based on three major points: (1) the definition of extent of upper gastrointestinal lesions by immediate fibroendoscopy; (2) immediate protection of the upper gastrointestinal tract by total parenteral nutrition in cases with serious burns (41 cases), normal oral nutrition being allowed for minor burns (35 cases); (3) reparative surgical procedures for any of the sequelae of such burns during the fibrosing phase. The results were as follows: (a) healing, depending upon the degree of burn, occurred between eight to 90 days; (b) the frequency of subsequent local complications was small with total parenteral nutrition started a few hours after ingestion of the corrosive product; (c) after reconstructive surgery no serious complications occurred; (d) the overall morbidity stayed at a very low level (four patients). We conclude that the general prognosis of a severe burn of the upper gastrointestinal tract, without other trauma, is appreciably improved by the very early institution of total parenteral nutrition.<\/jats:p>","DOI":"10.1136\/gut.21.5.370","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"370-375","source":"Crossref","is-referenced-by-count":92,"title":["New therapeutic approach to corrosive burns of the upper gastrointestinal tract."],"prefix":"10.1136","volume":"21","author":[{"given":"J","family":"Di Costanzo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Noirclerc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Jouglard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Escoffier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Cano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Gauthier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,5,1]]},"reference":[{"key":"ref_1","first-page":"590","article-title":"Veratzungen der Speiserohre","volume":"53","author":"Rudert, H.; Schmucker, K.; Beyer, D.","year":"1974","unstructured":"Rudert H, Schmucker K, Beyer D. Veratzungen der Speiserohre. Laryngol Rhinol Otol (Stuttg) 1974; 53: 590-9.","journal-title":"Laryngol Rhinol Otol (Stuttg)"},{"key":"ref_2","first-page":"70","article-title":"New therapeutic approach to corrosive burns of the uipper gastrointestinal tract scopy in caustic oesophagogastritis","volume":"60","year":"1973","unstructured":"New therapeutic approach to corrosive burns of the uipper gastrointestinal tract scopy in caustic oesophagogastritis. Am J Gastroenterol 1973; 60: 70-3.","journal-title":"Am J Gastroenterol"},{"key":"ref_3","first-page":"5","article-title":"Endoscopia de urgencia en ingestion de causticos","volume":"5","author":"Penaloza-Rojas, A.; Fassler, J.; Castaneda, L.E.","year":"1975","unstructured":"Penaloza-Rojas A, Fassler J, Castaneda LE. Endoscopia de urgencia en ingestion de causticos. Acta Endoscop 1975; 5: 5-6.","journal-title":"Acta Endoscop"},{"key":"ref_4","first-page":"680","article-title":"La localisation des lesions des voies digestives d'apres l'agent corrosif","volume":"87","author":"Savic, D.; Pejakovic, S.; Mihaljevic, B.","year":"1970","unstructured":"Savic D, Pejakovic S, Mihaljevic B. La localisation des lesions des voies digestives d'apres l'agent corrosif. Ann Otolaryngol Chir Cervicofac 1970; 87: 680-1.","journal-title":"Ann Otolaryngol Chir Cervicofac"},{"key":"ref_5","first-page":"389","article-title":"Criteres de 'guerison' des stenoses cicatricielles consecutives aux oesophagites corrosives","volume":"59","author":"Paris, J.; Heraud, M.; Paris, J.C.","year":"1970","unstructured":"Paris J, Heraud M, Paris JC. Criteres de 'guerison' des stenoses cicatricielles consecutives aux oesophagites corrosives. (Abstract.). Arch Fr Mal App Dig 1970; 59: 389.","journal-title":"(Abstract.). Arch Fr Mal App Dig"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1001\/archsurg.1975.01360120043008","article-title":"Fiberoptic endoscopy in treatment of corrosive injury of the stomach","volume":"110","author":"Chung, R.S.K.; Denbesten, L.","year":"1975","unstructured":"Chung RSK, Denbesten L. Fiberoptic endoscopy in treatment of corrosive injury of the stomach. Arch Surg 1975; 110: 725-8.","journal-title":"Arch Surg"},{"key":"ref_7","first-page":"4627","article-title":"Oesophagite corrosive","volume":"48","author":"Quincy, R.","year":"1972","unstructured":"Quincy R. Oesophagite corrosive. Cah Med Lyonnais 1972; 48: 4627-30.","journal-title":"Cah Med Lyonnais"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0022-4804(76)90100-1","article-title":"Modification of the experimental stent technique for esophageal burns","volume":"20","author":"Reyes, H.M.; Hill, J.L.","year":"1976","unstructured":"Reyes HM, Hill JL. Modification of the experimental stent technique for esophageal burns. J Surg Res 1976; 20: 65-70.","journal-title":"J Surg Res"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/thx.27.5.594","article-title":"Arguments against long-term conservative treatment of oesophageal strictures due to corrosive burns","volume":"27","author":"Imre, J.; Kopp, M.","year":"1972","unstructured":"Imre J, Kopp M. Arguments against long-term conservative treatment of oesophageal strictures due to corrosive burns. Thorax 1972; 27: 594-8.","journal-title":"Thorax"},{"issue":"34","key":"ref_10","first-page":"21","article-title":"Primary treatment of corrosive injuries of the esophagus in Denmark, in the period 1961-1970","volume":"10","author":"Fenger, H.J.; Johnsen, N.J.; Worsoe-Petersen, J.","year":"1975","unstructured":"Fenger HJ, Johnsen NJ, Worsoe-Petersen J. Primary treatment of corrosive injuries of the esophagus in Denmark, in the period 1961-1970. Scand J Gastroenterol 1975; 10: (abstract) suppl 34, 21-22.","journal-title":"Scand J Gastroenterol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1177\/000348946407300424","article-title":"A study of the management of caustic esophageal trauma","volume":"73","author":"CT, Jr, Yarington; GA, Bales; JP, Frazer","year":"1964","unstructured":"Yarington CT Jr, Bales GA, Frazer JP. A study of the management of caustic esophageal trauma. Ann Otol Rhinol Laryngol 1964; 73: 1130-35.","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"ref_12","first-page":"621","article-title":"La cortisone dans les oesophagites corrosives aigues. Pathogenie d'action et effet therapeutique","volume":"87","author":"Taillens, J.P.","year":"1970","unstructured":"Taillens JP. La cortisone dans les oesophagites corrosives aigues. Pathogenie d'action et effet therapeutique. Ann Otolaryngol Chir Cervicofac 1970; 87: 621-36.","journal-title":"Ann Otolaryngol Chir Cervicofac"},{"key":"ref_13","first-page":"\"930","article-title":"Bouginage and steroids used singly or in combination in experimental corrosive esophagitis","volume-title":"5Ragheb Ml, Ramadan AA, Khalia MA. Management of corrosive esophagitis","volume":"166","author":"Know, W.G.; Scott, JR, Zintel; HA, Guthrie; R, McCabe; R.E.","year":"1967","unstructured":"Know WG, Scott JR, Zintel HA, Guthrie R, McCabe RE. Bouginage and steroids used singly or in combination in experimental corrosive esophagitis. Ann Siurg 1967; 166: 930-41. '5Ragheb Ml, Ramadan AA, Khalia MA. Management of corrosive esophagitis. Suirg 1975; 79: 494-8."},{"key":"ref_14","first-page":"861","article-title":"BrCilures par ingestion de caustiques etude statistique a propos de 50 observations","volume":"22","author":"Bleicher, B.","year":"1973","unstructured":"Bleicher B. 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Rationale for agressive surgical approach","volume":"109","author":"Ray, J.F.; Myers, W.O.; Lawton, B.R.; Lee, F.Y.; Wenzel, F.J.; Sautter, R.D.","year":"1974","unstructured":"Ray JF, Myers WO, Lawton BR, Lee FY, Wenzel FJ, Sautter RD. 'The natural history of liquid lye ingestion. Rationale for agressive surgical approach. Arch Surg 1974; 109:436-9.","journal-title":"Arch Surg"},{"key":"ref_19","first-page":"115","article-title":"Causes precoces et tardives de la mort apres lesions corrosives de l'oesophage","volume":"85","author":"Podvinec, S.; Bogicevic, J.; Savic, D.; Jokanovic, D.","year":"1965","unstructured":"Podvinec S, Bogicevic J, Savic D, Jokanovic D. Causes precoces et tardives de la mort apres lesions corrosives de l'oesophage. Ann Otolaryng (Paris) 1965; 85: 115-26","journal-title":"Ann Otolaryng (Paris)"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.21.5.370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T09:15:42Z","timestamp":1765617342000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.21.5.370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,5]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1980,5,1]]},"published-print":{"date-parts":[[1980,5]]}},"alternative-id":["10.1136\/gut.21.5.370"],"URL":"https:\/\/doi.org\/10.1136\/gut.21.5.370","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1980,5]]}}}