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The addition of the unabsorbable disaccharide lactulose (in place of an equivalent amount of sucrose) accelerated small bowel transit time, but did not significantly influence gastric emptying. Thus, our results indicated that changes in small bowel transit time could occur independently of changes in gastric emptying in normal healthy subjects.<\/jats:p>","DOI":"10.1136\/gut.23.10.824","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"824-828","source":"Crossref","is-referenced-by-count":89,"title":["Is the transit time of a meal through the small intestine related to the rate at which it leaves the stomach?"],"prefix":"10.1136","volume":"23","author":[{"given":"N W","family":"Read","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Cammack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A M","family":"Holgate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Cann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1982,10,1]]},"reference":[{"key":"ref_1","article-title":"Regulation of gastric emptying","volume-title":"Handbook of Physiology, Sect 6: alimentary canal","volume":"4","author":"Hunt, J.N.; Knox, M.T.","year":"1968","unstructured":"Hunt JN, Knox MT. Regulation of gastric emptying. In: Handbook of Physiology, Sect 6: alimentary canal: vol. 4: Motility 1968; 1917-35."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1136\/gut.16.3.235","article-title":"Progress report: gastric emptying tests in man","volume":"16","author":"Sheiner, H.J.","year":"1975","unstructured":"Sheiner HJ. Progress report: gastric emptying tests in man. Gut 1975; 16: 235-45.","journal-title":"Gut"},{"key":"ref_3","first-page":"1276","article-title":"Read NW, Miles CA, Fisher D et al. Transit of a meal through the stomach, small intestine and colon in normal subjects and its role","volume-title":"the pathogenesis of diarrhea. Gastroenterology 1980; 79","unstructured":"Read NW, Miles CA, Fisher D et al. Transit of a meal through the stomach, small intestine and colon in normal subjects and its role in the pathogenesis of diarrhea. Gastroenterology 1980; 79: 1276-82."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/gut.17.3.189","article-title":"Simple clinical method of measuring gastric emptying of solid meals","volume":"17","author":"Ostick, D.G.; Green, G.; Howe, K.; Dymock, L.W.; Cowley, D.J.","year":"1976","unstructured":"Ostick DG, Green G, Howe K, Dymock LW, Cowley DJ. Simple clinical method of measuring gastric emptying of solid meals. Gut 1976; 17: 189-91.","journal-title":"Gut"},{"key":"ref_5","first-page":"546","article-title":"Investigation of small bowel transit time in man utilising pulmonary H2 measurements","volume":"85","year":"1974","unstructured":"Bond JH, Levitt MD. Investigation of small bowel transit time in man utilising pulmonary H2 measurements. J Lab Clin Med 1974; 85: 546-559.","journal-title":"J Lab Clin Med"},{"issue":"44","key":"ref_6","first-page":"787","article-title":"Rate of evacuation of various foods from the normal stomach","volume":"1929","author":"Wilson, M.J.; Dickson, W.H.; Singleton, A.C.","unstructured":"Wilson MJ, Dickson WH, Singleton AC. Rate of evacuation of various foods from the normal stomach. Arch Intern Med 1929; 44: 787-96. too rapid.","journal-title":"Arch Intern Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1113\/jphysiol.1966.sp007814","article-title":"The pattern of gastric emptying: a new To conclude, it would seem that, under view of old results","volume":"182","author":"Hopkins, A.","year":"1966","unstructured":"Hopkins A. The pattern of gastric emptying: a new To conclude, it would seem that, under view of old results. J Physiol 1966; 182: 144-9.","journal-title":"J Physiol"},{"key":"ref_8","first-page":"755","article-title":"Etude de la progression d'un repas dans l'intestin grele de l'homme par une methode scintigraphique","volume":"3","author":"Jian, R.; Pecking, A.; Najean, J.; Bernier, J.J.","year":"1979","unstructured":"Jian R, Pecking A, Najean J, Bernier JJ. Etude de la progression d'un repas dans l'intestin grele de l'homme par une methode scintigraphique. Gastroenterol Clin Biol 1979; 3: 755-62.","journal-title":"Gastroenterol Clin Biol"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.23.10.824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T11:54:31Z","timestamp":1765626871000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.23.10.824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,10]]},"references-count":8,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1982,10,1]]},"published-print":{"date-parts":[[1982,10]]}},"alternative-id":["10.1136\/gut.23.10.824"],"URL":"https:\/\/doi.org\/10.1136\/gut.23.10.824","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,10]]}}}