{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T20:05:48Z","timestamp":1765656348922,"version":"3.48.0"},"reference-count":22,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1984,4]]},"abstract":"<jats:p>In York between 1941 and 1949, 632 patients underwent Polya partial gastrectomy for peptic ulcer. Of 307 patients who were followed up in the York Gastric Clinic from 1971 to 1980, nine died of gastric cancer, three times the expected number. If gastrectomy was performed for gastric ulcer the risk of later development of carcinoma (7%) was significantly greater than that following operation for duodenal ulcer (1.6%) (p less than 0.001). No cancers were diagnosed in the 54 patients endoscoped. Atrophic gastritis was found in 98% of patients and intestinal metaplasia in 44%. Dysplasia was present in 35% but in no case was it severe. Although we have found that there is an increased risk of cancer developing in the gastric remnant we do not consider routine endoscopic follow up of all postgastrectomy patients to be a practical proposition.<\/jats:p>","DOI":"10.1136\/gut.25.4.393","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"393-397","source":"Crossref","is-referenced-by-count":25,"title":["Endoscopic examination of the gastric remnant 31-39 years after subtotal gastrectomy for peptic ulcer."],"prefix":"10.1136","volume":"25","author":[{"given":"I R","family":"Pickford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J L","family":"Craven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Hall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W D","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00000658-195614320-00003","article-title":"Cancer development in the gastric stump after partial gastrectomy for ulcer","volume":"143","author":"Helsingen, N.; Hillestad, L.","year":"1956","unstructured":"Helsingen N, Hillestad L. Cancer development in the gastric stump after partial gastrectomy for ulcer. Ann Surg 1956; 143: 173-9.","journal-title":"Ann Surg"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/BF02236057","article-title":"Late gastric carcinoma developing after surgery for benign conditions","volume":"15","author":"Kobayashi, S.; Prolla, J.C.; Kirsner, J.B.","year":"1970","unstructured":"Kobayashi S, Prolla JC, Kirsner JB. Late gastric carcinoma developing after surgery for benign conditions. Dig Dis 1970; 15: 905-12.","journal-title":"Dig Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/S0140-6736(71)90489-2","article-title":"Stomach cancer following gastric surgery for benign conditions","volume":"2","author":"Stalsberg, H.; Taksdal, S.","year":"1971","unstructured":"Stalsberg H, Taksdal S. Stomach cancer following gastric surgery for benign conditions. Lancet 1971; 2: 1175-7.","journal-title":"Lancet"},{"key":"ref_4","first-page":"256","article-title":"Carcinoma of the gastric stump after operation for benign gastro-duodenal ulcer","volume":"142","author":"Terjesen, T.; Erichsen, H.G.","year":"1976","unstructured":"Terjesen T, Erichsen HG. Carcinoma of the gastric stump after operation for benign gastro-duodenal ulcer. Acta Chir Scand 1976; 142: 256-60.","journal-title":"Acta Chir Scand"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00000658-197803000-00007","article-title":"Gastric carcinoma following operation for peptic ulcer disease","volume":"187","author":"Eberlein, T.J.; Lorenzo, F.V.; Webster, M.W.","year":"1978","unstructured":"Eberlein TJ, Lorenzo FV, Webster MW. Gastric carcinoma following operation for peptic ulcer disease. Ann Surg 1978; 187: 251-6.","journal-title":"Ann Surg"},{"article-title":"Gastric remnant carcinoma","author":"Bushkin, F.L.","key":"ref_6","unstructured":"Bushkin FL. Gastric remnant carcinoma. In: Bushkin FL, Woodward ER, eds. Postgastrectomy syndromes."},{"key":"ref_7","first-page":"106","article-title":"Major problems in clinical surgery. Vol 10","year":"1976","unstructured":"Major problems in clinical surgery. Vol 10. London and Philadelphia, W B Saunders, 1976: 106-13."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0002-9610(76)90284-1","article-title":"Late precancerous changes and carcinoma of the gastric stump after Billroth I resection","volume":"132","author":"Domellof, L.; Eriksson, S.; Janunger, K.-G.","year":"1976","unstructured":"Domellof L, Eriksson S, Janunger K-G. Late precancerous changes and carcinoma of the gastric stump after Billroth I resection. Am J Surg 1976; 132: 26-31.","journal-title":"Am J Surg"},{"key":"ref_9","first-page":"157","article-title":"Gastric carcinoma after partial gastrectomy","volume":"3","author":"J, De Boer; K, Huibregtse; GN, Tytgat","year":"1978","unstructured":"De Boer J, Huibregtse K, Tytgat GN. Gastric carcinoma after partial gastrectomy. Tijdschr Gastroenterol 1978; 3: 157-66.","journal-title":"Tijdschr Gastroenterol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/S0016-5085(19)32124-9","article-title":"Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection","volume":"73","author":"Domellof, L.; Eriksson, S.; Janunger, K.-G.","year":"1977","unstructured":"Domellof L, Eriksson S, Janunger K-G. Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection. Gastroenterology 1977; 73: 462-8.","journal-title":"Gastroenterology"},{"key":"ref_11","first-page":"467","article-title":"Mucosal changes in the gastric stump 20-25 years after partial gastrectomy","volume":"2","author":"Schrumpf, E.; Serck-Hanssen, A.; Stadaas, J.","year":"1977","unstructured":"Schrumpf E, Serck-Hanssen A, Stadaas J. Mucosal changes in the gastric stump 20-25 years after partial gastrectomy. Lancet 1977; 2: 467-9.","journal-title":"Lancet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/jcp.32.2.179","article-title":"Histological appearances of the gastric mucosa 15-27 years after partial gastrectomy","volume":"32","author":"Savage, A.; Jones, S.","year":"1979","unstructured":"Savage A, Jones S. Histological appearances of the gastric mucosa 15-27 years after partial gastrectomy. J Clin Pathol 1979; 32: 179-86.","journal-title":"J Clin Pathol"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000402324","article-title":"Endoscopic experience in the diagnosis of gastric stump cancer","volume":"5","author":"Giacosa, A.; Molinare, F.; Perasso, A.; Cheli, R.","year":"1979","unstructured":"Giacosa A, Molinare F, Perasso A, Cheli R. Endoscopic experience in the diagnosis of gastric stump cancer. Front Gastrointest Res 1979; 5: 160-3.","journal-title":"Front Gastrointest Res"},{"key":"ref_14","article-title":"Endoscopic screening for malignancy in the gastric remnant","volume-title":"2nd BSGISK & F Workshop on early gastric cancer","author":"Huibregtse, K.","year":"1981","unstructured":"Huibregtse K. Endoscopic screening for malignancy in the gastric remnant. In: Cotton P, ed. 2nd BSGISK & F Workshop on early gastric cancer. London: British Society of Gastroenterology, 1981."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0140-6736(48)90722-3","article-title":"Measured radical gastrectomy. Review of 505 operations for peptic ulcer","volume":"1","author":"Visick, A.H.","year":"1948","unstructured":"Visick AH. Measured radical gastrectomy. Review of 505 operations for peptic ulcer. Lancet 1948; 1: 505-10.","journal-title":"Lancet"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/jcp.25.1.1","article-title":"The histological diagnosis of chronic gastritis in fibre optic gastroscope biopsy specimens","volume":"25","author":"Whitehead, R.; Truelove, S.C.; Gear, M.W.L.","year":"1972","unstructured":"Whitehead R, Truelove SC, Gear MWL. The histological diagnosis of chronic gastritis in fibre optic gastroscope biopsy specimens. J Clin Pathol 1972; 25: 1-11.","journal-title":"J Clin Pathol"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","article-title":"The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification","volume":"64","author":"Lauren, P.","year":"1965","unstructured":"Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965; 64: 31-49.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"ref_18","first-page":"441","article-title":"Atrophic gastritis and its sequelae","volume":"9","author":"Siurala, M.; Lehtola, J.; Ihamaki, T.","year":"1974","unstructured":"Siurala M, Lehtola J, Ihamaki T. Atrophic gastritis and its sequelae. Scand J Gastroenterol 1974; 9: 441-6.","journal-title":"Scand J Gastroenterol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1365-2559.1979.tb02996.x","article-title":"A variant of intestinal metaplasia associated with gastric carcinoma: a histo-chemical study","volume":"3","author":"Jass, JR, Filipe; M.I.","year":"1979","unstructured":"Jass JR, Filipe MI. A variant of intestinal metaplasia associated with gastric carcinoma: a histo-chemical study. Histopathology 1979; 3: 191-9.","journal-title":"Histopathology"},{"issue":"16","key":"ref_20","first-page":"169","article-title":"Incidence of malignancies of the Billroth II operated stomach","volume":"67","author":"Stokkeland, M.; Schrumpf, E.; Serck-Hanssen, A.","year":"1981","unstructured":"Stokkeland M, Schrumpf E, Serck-Hanssen A et al. Incidence of malignancies of the Billroth II operated stomach. Scand J Gastroenterol 1981; suppl 67: 16: 169-71.","journal-title":"Scand J Gastroenterol"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/ijc.2910160107","article-title":"Microscopical cancer of the stomach. A study on histogenesis of gastric carcinoma","volume":"16","author":"Nagayo, T.","year":"1975","unstructured":"Nagayo T. Microscopical cancer of the stomach. A study on histogenesis of gastric carcinoma. Int J Cancer 1975; 16: 52-60.","journal-title":"Int J Cancer"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/1097-0142(197307)32:1<162::AID-CNCR2820320123>3.0.CO;2-D","article-title":"Histology of gastric cancer occurring after gastric surgery for benign conditions","volume":"32","author":"Taksdal, S.; Stalsberg, H.","year":"1973","unstructured":"Taksdal S, Stalsberg H. Histology of gastric cancer occurring after gastric surgery for benign conditions. Cancer 1973; 32: 162-6.","journal-title":"Cancer"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.25.4.393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T20:03:49Z","timestamp":1765656229000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.25.4.393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,4]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1984,4,1]]},"published-print":{"date-parts":[[1984,4]]}},"alternative-id":["10.1136\/gut.25.4.393"],"URL":"https:\/\/doi.org\/10.1136\/gut.25.4.393","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1984,4]]}}}