{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T06:28:31Z","timestamp":1765607311083,"version":"3.48.0"},"reference-count":44,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1984,4]]},"abstract":"<jats:p>Heroin abusers are frequently found to have abnormal liver function tests and hepatic histology. Hepatitis viruses A, B, and NANB, other drugs or drug contaminants and excessive alcohol consumption are factors thought to contribute. One hundred and sixteen heroin abusers attending a London treatment centre were studied. Sixty two (53%) had a raised aspartate transaminase. This was not explained by current infection with hepatitis A and B, cytomegalo or Epstein-Barr viruses, excessive alcohol consumption (greater than 80 g\/day) or concomitant drug taking. Abnormal liver function tests were as frequent in those with markers of current or past HBV infection as those without and there was evidence that both HBV infection and the cause of the abnormal liver function tests were acquired in the first few years of intravenous drug abuse. Liver biopsies from eight patients showed chronic hepatitis with a mild lobular and portal inflammatory infiltrate, fatty change and prominent sinusoidal cells. Electron microscopy showed cytoplasmic trilaminar tubular structures and dense fused membranes in dilated endoplasmic reticulum. These clinical, biochemical, serological, and histological features would suggest a major role for NANB virus infection in the aetiology of hepatitis in heroin abusers.<\/jats:p>","DOI":"10.1136\/gut.25.4.417","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"417-423","source":"Crossref","is-referenced-by-count":24,"title":["Clinical, biochemical, serological, histological and ultrastructural features of liver disease in drug abusers."],"prefix":"10.1136","volume":"25","author":[{"given":"I V","family":"Weller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Cohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Sierralta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Mitcheson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Montano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Scheuer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H C","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1111\/j.1445-5994.1974.tb03215.x","article-title":"The covert liver disease of drug addicts","volume":"4","author":"Ireton, H.J.C.; Gust, I.D.; Moon, W.J.; Lehman, N.; Stening, G.F.; Smallwood, R.","year":"1974","unstructured":"Ireton HJC, Gust ID, Moon WJ, Lehman N, Stening GF, Smallwood R. 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Studies on the diagnostic value of an immunofluorescence test for E.B. virus specific IgM. J Clin Pathol 1974; 27: 647-5 1.","journal-title":"J Clin Pathol"},{"key":"ref_21","article-title":"Prevalence of a non-A, non-B associated antigen\/antibody system detected by radioimmunoassay in acute and chronic liver disease","author":"Luo, K.X.; Karayiannis, P.; Bamber, M.; Kernoff, P.; Thomas, H.V.; Sherlock, S.","year":"1983","unstructured":"Luo KX, Karayiannis P, Bamber M, Kernoff P, Thomas HV, Sherlock S. Prevalence of a non-A, non-B associated antigen\/antibody system detected by radioimmunoassay in acute and chronic liver disease. J Med Virol 1983 (In press).","journal-title":"J Med Virol"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/oxfordjournals.aje.a121161","article-title":"The serum hepatitis related antigen (SH) in illicit drug users","volume":"91","author":"Cherubin, C.E.; Hargrove, R.L.; Prince, A.","year":"1970","unstructured":"Cherubin CE, Hargrove RL, Prince A. The serum hepatitis related antigen (SH) in illicit drug users. Am J Epidemiol 1970; 91: 510-7.","journal-title":"Am J Epidemiol"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF01642145","article-title":"Studies on antibody to hepatitis. A virus in children and adults in London","volume":"7","author":"Damjanovic, V.; Ross, M.; Brumfitt, W.","year":"1979","unstructured":"Damjanovic V, Ross M, Brumfitt W. Studies on antibody to hepatitis. A virus in children and adults in London. 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Demonstration of two different types of non-A, non-B hepatitis by re-injection and cross challenge studies in chimpanzees. Gastroenterology 1981; 81: 107-13."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1136\/jcp.34.10.1175","article-title":"Clinical and histological features of a group of patients with sporadic non-A, non-B hepatitis","volume":"34","author":"Bamber, M.; Murray, A.K.; Weller, I.V.D.","year":"1981","unstructured":"Bamber M, Murray AK, Weller IVD, et al. Clinical and histological features of a group of patients with sporadic non-A, non-B hepatitis. J Clin Pathol 1981; 34: 1175-80.","journal-title":"J Clin Pathol"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1136\/gut.22.10.854","article-title":"Short incubation non-A, non-B hepatitis transmitted by factor VIII concentrate in patients with congenital coagulation disorders","volume":"22","author":"Bamber, M.; Murray, A.; Arborgh, B.A.M.","year":"1981","unstructured":"Bamber M, Murray A, Arborgh BAM, et al. Short incubation non-A, non-B hepatitis transmitted by factor VIII concentrate in patients with congenital coagulation disorders. Gut 1981; 22: 854-9.","journal-title":"Gut"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0046-8177(81)80328-0","article-title":"Modern aspects of the morphology of viral hepatitis","volume":"12","author":"Phillips, M.J.; Powell, S.","year":"1981","unstructured":"Phillips MJ, Powell S. Modern aspects of the morphology of viral hepatitis. 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Lancet 1979; 1: 1249-50.","journal-title":"Lancet"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1126\/science.451589","article-title":"Non-A. non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees","volume":"205","author":"Shimizu, Y.K.; Feinstone, S.M.; Purcell, R.H.; Alter, H.J.; London, W.T.","year":"1979","unstructured":"Shimizu YK, Feinstone SM, Purcell RH, Alter HJ, London WT. Non-A. non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees. Science 1979; 205: 197-200.","journal-title":"Science"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/1096-9071(1980)5:4<317::AID-JMV1890050408>3.0.CO;2-H","article-title":"Intranuclear virus-like particles in a case of sporadic non-A, non-B hepatitis","volume":"5","author":"Gmelin, K.; Kommerell, B.; Walherr, R.; Ehrlich, B.V.","year":"1980","unstructured":"Gmelin K, Kommerell B, Walherr R, Ehrlich BV. Intranuclear virus-like particles in a case of sporadic non-A, non-B hepatitis. J Med Virol 1980; 5: 317-22.","journal-title":"J Med Virol"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1056\/NEJM198010023031417","article-title":"Hepatic intranuclear particles in patients with non-A, non-B hepatitis","volume":"303","author":"Grimaud, J.A.; Peyrol, S.; Vituiski, L.; Chevallier-Queyron, P.; Trepo, C.","year":"1980","unstructured":"Grimaud JA, Peyrol S, Vituiski L, Chevallier-Queyron P, Trepo C. 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J Med Virol 1981: 8: 267-75.","journal-title":"J Med Virol"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/hep.1840010603","article-title":"Chronic non-A, non-B hepatitis: ultrastructural and serologic studies","volume":"1","author":"Marciano-Cabral, R.; Rublee, K.L.; Carithers, R.L.; Galen, E.A.; Sobieski, T.J.; Cabral, G.A.","year":"1981","unstructured":"Marciano-Cabral R, Rublee KL, Carithers RL, Galen EA, Sobieski TJ, Cabral GA. Chronic non-A, non-B hepatitis: ultrastructural and serologic studies. Hepatology 1981; 1: 575-82.","journal-title":"Hepatology"},{"key":"ref_36","first-page":"85","article-title":"Interchromatin granules","volume-title":"The cell nucleus \"nuclear particles\" Part A","author":"Puvion, E.; Mayne, G.","year":"1980","unstructured":"Puvion E, Mayne G. Interchromatin granules. In Busch H, ed. The cell nucleus \"nuclear particles\" Part A. Academic Press 1980; 85-90."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/jmv.1890070304","article-title":"Ultrastructural changes in the liver of patients with chronic non-A, non-B hepatitis","volume":"7","author":"Busachi, C.A.; Realdi, G.; Alberti, A.; Badiali-De Georgi, L.; Tremolada, F.","year":"1981","unstructured":"Busachi CA, Realdi G, Alberti A, Badiali-De Georgi L, Tremolada F. Ultrastructural changes in the liver of patients with chronic non-A, non-B hepatitis. J Med Virol 1981; 7: 205-12.","journal-title":"J Med Virol"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0016-5085(82)80399-5","article-title":"non-B (Type 1) hepatitis agent capable of inducing tubular ultrastructures in the hepatocyte cytoplasm of chimpanzees: inactivation by formalin and heat","volume":"82","author":"Yoshizawa, H.; Itoh, Y.; Iwarkiri, S.","year":"1982","unstructured":"Yoshizawa H, Itoh Y, Iwarkiri S et al. 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McGraw Hill 1979: 27-9."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1600-0676.1981.tb00021.x","article-title":"Human non-A, non-B hepatitis: ultrastructural alterations in hepatocytes","volume":"1","author":"C, De Wolf-Peters; R, De Vos; V, Desmet","year":"1981","unstructured":"De Wolf-Peters C, De Vos R, Desmet V, et al. Human non-A, non-B hepatitis: ultrastructural alterations in hepatocytes. Liver 1981; 1: 50-5.","journal-title":"Liver"},{"key":"ref_42","first-page":"41","article-title":"Ultrastructural changes in the liver in experimental non-A, non-B hepatitis","volume":"62","author":"Tsiquaye, K.N.; Amini, S.; Kessler, H.; Bird, R.G.; Tovey, G.; Zuckerman, A.J.","year":"1981","unstructured":"Tsiquaye KN, Amini S, Kessler H, Bird RG, Tovey G, Zuckerman AJ. Ultrastructural changes in the liver in experimental non-A, non-B hepatitis. 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