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Well nourished patients with Crohn's disease were similar to the two control groups. Twenty one undernourished patients with Crohn's disease were also followed during the course of two to four months' nutritional treatment with an enteral supplement. Nutritional therapy was associated with significant anthropometric gains as well as significant rises in total lymphocyte and T lymphocyte counts. Serum orosomucoids were significantly higher in undernourished patients and decreased significantly during nutritional therapy. The results show that undernutrition and disease acuity may be associated with reduced immunological competence in patients with Crohn's disease, but all these measurements can be improved by short term nutritional treatment.<\/jats:p>","DOI":"10.1136\/gut.25.5.465","type":"journal-article","created":{"date-parts":[[2007,9,7]],"date-time":"2007-09-07T20:55:35Z","timestamp":1189198535000},"page":"465-472","source":"Crossref","is-referenced-by-count":25,"title":["Influence of nutritional status on immune functions in patients with Crohn's disease."],"prefix":"10.1136","volume":"25","author":[{"given":"A D","family":"Harries","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V A","family":"Danis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R V","family":"Heatley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0016-5085(19)32666-6","article-title":"T cells in Crohn's disease","volume":"69","author":"Strickland, R.; Williams, R.","year":"1975","unstructured":"Strickland R, Williams R. 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