{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:52:50Z","timestamp":1765605170105,"version":"3.48.0"},"reference-count":20,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1985,11]]},"abstract":"<jats:p>We used an indirect immunofluorescence technique, using rabbit antisera against cereal protein extracts, to determine which cereal proteins bind to reticulin in tissue sections and which do not. Wheat albumin extracts and globulins and gliadin extracts from a range of different wheat varieties, and prolamine extracts of barley and rye each bound to reticulin in vitro, while prolamine extracts of maize and rice did not. Wheat gluten subfractions were also tested. Subfractions B and C and subfractions B2 and B3 did bind, but fraction A and subfraction B1 did not. The results suggest an association between in vitro reticulin binding and the ability to induce gluten sensitive enteropathy on feeding.<\/jats:p>","DOI":"10.1136\/gut.26.11.1204","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1204-1209","source":"Crossref","is-referenced-by-count":4,"title":["Does the reticulin binding property of cereal proteins demonstrable in vitro have pathogenetic significance for coeliac disease?"],"prefix":"10.1136","volume":"26","author":[{"given":"D J","family":"Unsworth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E J","family":"Holborow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/1523-1747.ep12525376","article-title":"Binding of wheat gliadin in vitro to reticulin in normal and dermatitis herpetiformis skin","volume":"76","author":"Unsworth, D.J.; Johnson, G.D.; Haffeden, G.; Fry, L.; Holborow, E.J.","year":"1981","unstructured":"Unsworth DJ, Johnson GD, Haffeden G, Fry L, Holborow EJ. Binding of wheat gliadin in vitro to reticulin in normal and dermatitis herpetiformis skin. J Invest Dermatol 1981; 76: 88-93.","journal-title":"J Invest Dermatol"},{"key":"ref_2","first-page":"1202","article-title":"Ultrastructural changes suggestive of immune reactions in the jejunal mucosa of coeliac children following gluten challenge","volume":"1","author":"Shiner, M.","year":"1973","unstructured":"Shiner M. Ultrastructural changes suggestive of immune reactions in the jejunal mucosa of coeliac children following gluten challenge. Lancet 1973; 1: 1202.","journal-title":"Lancet"},{"key":"ref_3","first-page":"311","article-title":"Anti-reticulin antibody: Incidence and diagnostic significance","volume":"14","author":"Seah, P.P.; Fry, L.; Holborow, E.J.; Rossiter, M.A.","year":"1983","unstructured":"Seah PP, Fry L, Holborow EJ, Rossiter MA, et al. Anti-reticulin antibody: Incidence and diagnostic significance. 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Q J Med 1978; 185: 101.","journal-title":"Q J Med"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.26.11.1204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:49:53Z","timestamp":1765604993000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.26.11.1204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,11]]},"references-count":20,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1985,11,1]]},"published-print":{"date-parts":[[1985,11]]}},"alternative-id":["10.1136\/gut.26.11.1204"],"URL":"https:\/\/doi.org\/10.1136\/gut.26.11.1204","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1985,11]]}}}