{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:24:34Z","timestamp":1789500274802,"version":"build-2803163510"},"reference-count":17,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:p>The effect of Yag laser photocoagulation on the course of bleeding of gastrointestinal vascular malformations was studied in 59 patients, with a total of 482 lesions. The lesions were located in the upper gastrointestinal tract alone in 25 patients, in the lower tract alone in 31 patients and in both the lower and the upper gastrointestinal tract in three patients. In the month before laser therapy the number of bleeding episodes averaged 1.09 +\/- 0.6 (SD) per patient (n = 57) and the transfusion requirements 2.4 +\/- 2.6 red blood cells units per patient, while in the month after treatment the bleeding incidence averaged 0.16 +\/- 0.5 and the transfusion requirements 0.21 +\/- 0.8 (both p less than 0.001). Long term results were analysed considering for each patient an equally long pretreatment and follow up period. After a mean follow up period of 11.5 months (1-48 months), 17 of the 57 patients available for follow up rebled. The reduction of the bleeding rate was statistically significant at one, six, 12, and 18 months of follow up, while transfusion rate was significantly decreased at one, six, and 12 months. The results were disappointing in patients with Osler-Weber-Rendu (n = 4) and in patients with angiomas associated with Von Willebrand's disease (n = 3), who all rebled. In angiodysplasia the treatment was successful in 82% of the 49 patients. The more numerous the lesions, the less effective the reduction in bleeding rate by laser treatment was. Histological studies showed that the haemostatic effect of Yag laser photocoagulation was obtained by destruction of the lesion. Rebleeding was due to lesions missed at the first treatment, incompletely treated lesions and recurrence of new lesions. In two patients a free caecal perforation necessitated a right hemicolectomy. In both patients numerous or very large lesions had been treated in the caecum.<\/jats:p>","DOI":"10.1136\/gut.26.6.586","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"586-593","source":"Crossref","is-referenced-by-count":126,"title":["Long term results of treatment of vascular malformations of the gastrointestinal tract by neodymium Yag laser photocoagulation."],"prefix":"10.1136","volume":"26","author":[{"given":"P","family":"Rutgeerts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Van Gompel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Geboes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Vantrappen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Broeckaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Coremans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1985,6,1]]},"reference":[{"key":"ref_1","first-page":"430","article-title":"Bleeding vascular malformations of the intestine","volume":"84","author":"Richardson, J.D.; Max, M.H.; LM, Jr, Flint; Schweisinger, W.; Howard, M.; Aust, J.B.","year":"1978","unstructured":"Richardson JD, Max MH, Flint LM Jr, Schweisinger W, Howard M, Aust JB. 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Surg Gynecol Obstet 1979; 149: 353-9.","journal-title":"Surg Gynecol Obstet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2214\/ajr.131.1.157","article-title":"Successful transcatheter gelfoam embolisation of a bleeding vascular ectasia","volume":"131","author":"Sinderman, K.W.; Franklin, J.; Sos, T.A.","year":"1978","unstructured":"Sinderman KW, Franklin J, Sos TA. Successful transcatheter gelfoam embolisation of a bleeding vascular ectasia. Am J Roentgenol Rad Ther Nucl Med 1978; 131: 157-9.","journal-title":"Am J Roentgenol Rad Ther Nucl Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1055\/s-0028-1098566","article-title":"Recurrent gastrointestinal bleeding in Osler's disease successfully treated by endoscopic electrocoagulation in the stomach","volume":"7","author":"Weingart, J.; Elster, K.; Ottenjann, R.","year":"1975","unstructured":"Weingart J, Elster K, Ottenjann R. 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Lancet 1982; 2: 16-9.","journal-title":"Lancet"},{"key":"ref_8","first-page":"1093","article-title":"Endoscopic treatment of hemangiomata with Argon laser in patients with gastrointestinal bleeding","volume":"82","author":"Jensen, D.M.; Machicado, G.A.; Tapia, J.I.","year":"1982","unstructured":"Jensen DM, Machicado GA, Tapia JI et al. Endoscopic treatment of hemangiomata with Argon laser in patients with gastrointestinal bleeding. Gastroenterology 1982; 82: 1093.","journal-title":"Gastroenterology"},{"key":"ref_9","first-page":"126","article-title":"Argon laser photocoagulation of vascular malformations of the GI tract: short term results","volume":"28","author":"Bowers, J.H.; Dixon, J.A.","year":"1982","unstructured":"Bowers JH, Dixon JA. Argon laser photocoagulation of vascular malformations of the GI tract: short term results. 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Gastrointest Endosc 1982; 28: 2: 148.","journal-title":"Gastrointest Endosc"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1001\/archsurg.1976.01360220077013","article-title":"Arteriovenous malformations of the gastrointestinal tract","volume":"111","author":"Moore, J.D.; Thompson, N.W.; Appelman, H.D.","year":"1976","unstructured":"Moore JD, Thompson NW, Appelman HD. Arteriovenous malformations of the gastrointestinal tract. Arch Surg 1976; 111: 381-9.","journal-title":"Arch Surg"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/BF01295651","article-title":"Comparative study of the effects of argon and Neodymium Yag laser beams on the normal fundic wall in the beagle dog","volume":"27","author":"Etienne, J.; Dorme, N.; Ladouch-Badre, A.; Raimbert, P.; Berthier, J.P.; Sultan, R.","year":"1982","unstructured":"Etienne J, Dorme N, Ladouch-Badre A, Raimbert P, Berthier JP, Sultan R. 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Controlled trial of Yag laser treatment of upper digestive hemorrhage. Gastroenterology 1982; 83: 4106.","journal-title":"Gastroenterology"},{"key":"ref_16","first-page":"263","article-title":"Neodymium Yag laser photocoagulation for haemostasis of gastrointestinal non-variceal hemorrhage","volume-title":"Z Gastroenterol","volume":"21","author":"Rutgeerts, P.; Vantrappen, G.; Geboes, K.; Broeckaert, L.","year":"1983","unstructured":"Rutgeerts P, Vantrappen G, Geboes K, Broeckaert L. Neodymium Yag laser photocoagulation for haemostasis of gastrointestinal non-variceal hemorrhage. Z Gastroenterol 1983; 21: 263-7."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0016-5107(84)72359-5","article-title":"The influence of 15 (R) 15 Methyl PGE2 on Nd Yag laser induced gastric ulcers","volume":"30","year":"1984","unstructured":"The influence of 15 (R) 15 Methyl PGE2 on Nd Yag laser induced gastric ulcers. Gastrointest Endosc 1984; 30: 173-8.","journal-title":"Gastrointest Endosc"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.26.6.586","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:25:44Z","timestamp":1765603544000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.26.6.586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,6]]},"references-count":17,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1985,6,1]]},"published-print":{"date-parts":[[1985,6]]}},"alternative-id":["10.1136\/gut.26.6.586"],"URL":"https:\/\/doi.org\/10.1136\/gut.26.6.586","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"value":"0017-5749","type":"print"},{"value":"1468-3288","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,6]]}}}