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In view of the low plasma prednisolone concentrations obtained, there are theoretical advantages in using a poorly absorbed enema to avoid the possibility of systemic steroid effects in patients requiring long term steroid treatment.<\/jats:p>","DOI":"10.1136\/gut.26.8.822","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"822-824","source":"Crossref","is-referenced-by-count":49,"title":["Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis."],"prefix":"10.1136","volume":"26","author":[{"given":"P B","family":"McIntyre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F A","family":"Macrae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Berghouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"English","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J E","family":"Lennard-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,8,1]]},"reference":[{"issue":"1","key":"ref_1","first-page":"165","article-title":"Intra-rectal treatment of 100 cases of ulcerative colitis with prednisolone-21-phosphate enemata","volume":"1961","author":"Matts, S.G.F.","unstructured":"Matts SGF. 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