{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:33:08Z","timestamp":1761561188391,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut"],"published-print":{"date-parts":[[1986,11]]},"abstract":"<jats:p>The absorption of 14C triolein in a standard fat meal was measured in 60 controls and 66 patients with gastrointestinal disorders by 14CO2 breath sampling. A reference range based upon cumulative eight hour values of the controls was independent of height, weight, and sex. The range was of log normal distribution and declined with age (p less than 0.05). Acceptable 'within-day' and 'between-day' reproducibility was found. All patients tested with untreated coeliac disease, pancreatic insufficiency and most with symptomatic small intestinal Crohn's disease had subnormal values. Twenty per cent of those with irritable bowel syndrome had subnormal values. Patients with ulcerative colitis were all normal. The reagents used and the breath samples after collection were stable. In our experience the 14C triolein test is simple, inexpensive, and helpful in the detection of diseases associated with fat malabsorption. It is of value in monitoring the response to treatment of individual patients with coeliac disease.<\/jats:p>","DOI":"10.1136\/gut.27.11.1347","type":"journal-article","created":{"date-parts":[[2007,9,18]],"date-time":"2007-09-18T17:41:31Z","timestamp":1190137291000},"page":"1347-1352","source":"Crossref","is-referenced-by-count":15,"title":["14C triolein breath test: a routine test in the gastroenterology clinic?"],"prefix":"10.1136","volume":"27","author":[{"given":"K","family":"Mylvaganam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P R","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1080\/00365521.1984.12005734","article-title":"Faecal fat and faecal weight - reproducibility and diagnostic efficiency of various regimens","volume":"19","author":"N, Thorsgaard Pedersen; H, Halgreen","year":"1984","unstructured":"Thorsgaard Pedersen N, Halgreen H. Faecal fat and faecal weight - reproducibility and diagnostic efficiency of various regimens. Scand J Gastroenterol 1984; 19: 350-4.","journal-title":"Scand J Gastroenterol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/000456328402100301","article-title":"Have chemical tests a role in diagnosing malabsorption?","volume":"21","author":"Theodossi, A.; Gazzard, B.G.","year":"1984","unstructured":"Theodossi A, Gazzard BG. Have chemical tests a role in diagnosing malabsorption? Ann Clin Biochemn 1984; 21: 153-65.","journal-title":"Ann Clin Biochemn"},{"key":"ref_3","first-page":"1634","article-title":"The absorption and disposition of orally administered 1131 labelled neutral fat in man","volume":"34","author":"Stanley, M.M.; Thannhauser, S.J.","year":"1949","unstructured":"Stanley MM, Thannhauser SJ. The absorption and disposition of orally administered 1131 labelled neutral fat in man. J Lab Clin Med 1949; 34: 1634-39.","journal-title":"J Lab Clin Med"},{"key":"ref_4","article-title":"Clinical investigation of patients with malabsorption and diarrhoea","volume-title":"Textbook of gastroenterology","author":"Chadwick, V.S.","unstructured":"Chadwick VS. Clinical investigation of patients with malabsorption and diarrhoea. In: Bouchier IAD. Allan RN, Hodgson HJF, Keighley MRB, eds. Textbook of gastroenterology. London: Bailliere Tindall, 1984: 438."},{"key":"ref_5","first-page":"6","article-title":"Triolein breath test. A sensitive and specific test for fat malabsorption","volume":"76","author":"Newcomer, A.D.; Hofmann, A.F.; Dimagno, E.P.; Thomas, P.J.; Carlson, G.L.","year":"1979","unstructured":"Newcomer AD, Hofmann AF, Dimagno EP, Thomas PJ, Carlson GL. Triolein breath test. A sensitive and specific test for fat malabsorption. Gastroenterology, 1979; 76: 6-13.","journal-title":"Gastroenterology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1136\/bmj.282.6275.1501","article-title":"Comparison of simple screening tests for fat malabsorption","volume":"282","author":"West, P.S.; Levin, G.E.; Griffin, G.E.; Maxwell, J.D.","year":"1981","unstructured":"West PS, Levin GE, Griffin GE, Maxwell JD. Comparison of simple screening tests for fat malabsorption. Br Med J 1981; 282: 1501-4.","journal-title":"Br Med J"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/00365528309181550","article-title":"C-Triolein breath test as a rapid and convenient screening test for fat malabsorption","volume":"18","year":"1983","unstructured":"C-Triolein breath test as a rapid and convenient screening test for fat malabsorption. Scand J Gastroenterol 1983; 18: 9-12.","journal-title":"Scand J Gastroenterol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1445-5994.1984.tb04270.x","article-title":"Clinical evaluation of the 14C-triolein breath test: a Critical Analysis","volume":"14","author":"Butler, R.N.; Lawson, M.J.; Gehling, N.J.; Kerr Grant, A.","year":"1984","unstructured":"Butler RN, Lawson MJ, Gehling NJ, Kerr Grant A. Clinical evaluation of the 14C-triolein breath test: a Critical Analysis. Aust N Z J Med 1984; 14: 111-13.","journal-title":"Aust N Z J Med"},{"key":"ref_9","first-page":"400","article-title":"Measurement of intestinal fat absorption with carbon-14 labelled tracers","volume":"71","author":"Kaihara, S.; Wagner, H.N.","year":"1968","unstructured":"Kaihara S,Wagner HN. Measurement of intestinal fat absorption with carbon-14 labelled tracers. J Lab Clin Med 1968; 71: 400-11.","journal-title":"J Lab Clin Med"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0009-8981(80)90150-3","article-title":"Percy-Robb IW. The glyceryl (14C) tripalmitate breath test: A reassessment","volume":"103","author":"Strange, R.C.; Reid, J.; Holton, D.; Jewell, N.P.","year":"1980","unstructured":"Strange RC, Reid J, Holton D, Jewell NP, Percy-Robb IW. The glyceryl (14C) tripalmitate breath test: A reassessment. Clin Chim Acta 1980; 103: 317-23.","journal-title":"Clin Chim Acta"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1136\/bmj.290.6469.665","article-title":"Is bile acid malabsorption underdiagnosed? An evaluation of diagnosis by measurement of SeHCAT retention","volume":"290","author":"Merrick, M.V.; Eastwood, M.A.; Ford, M.J.","year":"1985","unstructured":"Merrick MV, Eastwood MA, Ford MJ. Is bile acid malabsorption underdiagnosed? An evaluation of diagnosis by measurement of SeHCAT retention. Br Med J 1985; 290: 665-8.","journal-title":"Br Med J"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/gut.17.12.965","article-title":"Idiopathic bile acid catharsis","volume":"17","author":"Thaysen, E.H.; Pedersen, L.","year":"1976","unstructured":"Thaysen EH, Pedersen L. Idiopathic bile acid catharsis. Gut 1976; 17: 965-70.","journal-title":"Gut"}],"container-title":["Gut"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/gut.27.11.1347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T18:16:07Z","timestamp":1757268967000},"score":1,"resource":{"primary":{"URL":"https:\/\/gut.bmj.com\/lookup\/doi\/10.1136\/gut.27.11.1347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,11]]},"references-count":12,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1986,11,1]]},"published-print":{"date-parts":[[1986,11]]}},"alternative-id":["10.1136\/gut.27.11.1347"],"URL":"https:\/\/doi.org\/10.1136\/gut.27.11.1347","relation":{},"ISSN":["0017-5749","1468-3288"],"issn-type":[{"type":"print","value":"0017-5749"},{"type":"electronic","value":"1468-3288"}],"subject":[],"published":{"date-parts":[[1986,11]]}}}